1) Bhandari M, Guyatt G, Walter SD, et al. Randomized trial of reamed and unreamed intramedullary nailing of tibial shaft fractures. J Bone Jt Surg - Ser A. 2008;90(12):2567-2578. doi:10.2106/JBJS.G.01694
2) Vallier HA, Le TT, Bedi A. Radiographic and clinical comparisons of distal tibia shaft fractures (4 to 11 cm proximal to the plafond): Plating versus intramedullary nailing. J Orthop Trauma. 2008;22(5):307-311. doi:10.1097/BOT.0b013e31816ed974
3) Gross SC, Galos DK, Taormina DP, Crespo A, Egol KA, Tejwani NC. Can Tibial Shaft Fractures Bear Weight After Intramedullary Nailing? A Randomized Controlled Trial. J Orthop Trauma. 2016;30(7):370-375. doi:10.1097/BOT.0000000000000598J Orthop Trauma 2016;30:370–376
4) Rommens PM, Küchle R, Hofmann A, Hessmann MH. Intramedullary nailing of metaphyseal fractures of the lower extremity. Acta Chir Orthop Traumatol Cech. Published online 2017.
5) Režen T, Kovanda A, Eiken O, Mekjavic IB, Rogelj B. Expression changes in human skeletal muscle miRNAs following 10 days of bed rest in young healthy males. Acta Physiol. Published online 2014. doi:10.1111/apha.12228
6) Xia L, Cheung KK, Yeung SS, Yeung EW. The involvement of transient receptor potential canonical type 1 in skeletal muscle regrowth after unloading-induced atrophy. J Physiol. 2016;594(11):3111-3126. doi:10.1113/JP271705
7) Buckwalter JA, Grodzinsky AJ. Loading of healing bone, fibrous tissue, and muscle: implications for orthopaedic practice. J Am Acad Orthop Surg. 1999;7(5):291-299. doi:10.5435/00124635-199909000-00002
8) Muller ME, Nazarian S, Koch, et al. The comprehensive classification of fractures of long bones. Berlin: Springer, 1990
9) Pogliacomi F, Schiavi P, Calderazzi F, Ceccarelli F, Vaienti E. When is indicated fibular fixation in extra-articular fractures of the distal tibia? Acta Biomed. 2018;89(4):558-563. doi:10.23750/abm.v89i4.7775
10) Wood DJ, Ions GK, Quinby JM, Gale DW, Stevens J. Factors which influence mortality after subcapital hip fracture. J Bone Jt Surg - Ser B. Published online 1992. doi:10.1302/0301- 620x.74b2.1544951
11) Parker MJ, Palmer CR. A new mobility score for predicting mortality after hip fracture. J Bone Jt Surg - Ser B. Published online 1993. doi:10.1302/0301-620x.75b5.8376443
12) Ions GK, Stevens J. Prediction of survival in patients with femoral neck fractures. J Bone Jt Surg - Ser B. Published online 1987. doi:10.1302/0301-620x.69b3.3584189
13) Kanda Y. Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplant. 2013;48(3):452-458. doi:10.1038/bmt.2012.244
14) Court-Brown CM, Christie J, McQueen MM. Closed intramedullary tibial nailing. Its use in closed and type I open fractures. J Bone Jt Surg - Ser B. Published online 1990. doi:10.1302/0301-620x.72b4.2380211
15) Ruiz AL, Kealey WDC, McCoy GF. Implant failure in tibial nailing. Injury. 2000;31(5):359-362. doi:10.1016/S0020-1383(00)00002-4
16) Boenisch UW, De Boer PG, Journeaux SF. Unreamed intramedullary tibial nailing - Fatigue of locking bolts. Injury. Published online 1996. doi:10.1016/0020-1383(95)00150-6
17) Krettek C, Haas N, Schandelmaier P, Frigg R, Tscherne H. The unreamed tibial nail (UTN) for tibial shaft fractures with severe soft tissue damage. First clinical experience. Unfallchirurg. Published online 1991.
18) Whittle AP, Russell TA, Taylor JC, Lavelle DG. Treatment of open fractures of the tibial shaft with the use of interlocking nailing without reaming. J Bone Jt Surg - Ser A. Published online 1992. doi:10.2106/00004623-199274080-00005
19) Hansen M, Mehler D, Hessmann MH, Blum J, Rommens PM. Intramedullary stabilization of extraarticular proximal tibial fractures: A biomechanical comparison of intramedullary and extramedullary implants including a new Proximal Tibia Nail (PTN). J Orthop Trauma. Published online 2007.doi:10.1097/BOT.0b013e31815aba5e
20) Schemitsch EH, Bhandari M, Guyatt G, et al. Prognostic factors for predicting outcomes after intramedullary nailing of the Tibia. J Bone Jt Surg - Ser A. 2012;94(19):1786-1793. doi:10.2106/JBJS.J.01418
21) Hernández-Vaquero D, Suárez-Vázquez A, Iglesias-Fernández S, García-García J, Cervero-Suárez J. Dynamisation and early weight-bearing in tibial reamed intramedullary nailing: Its safety and effect on fracture union. Injury. 2012;43(SUPPL. 2):63-67. doi:10.1016/S0020-1383(13)70182-7
22) Houben IB, Raaben M, Van Basten Batenburg M, Blokhuis TJ. Delay in weight bearing in surgically treated tibial shaft fractures is associated with impaired healing: a cohort analysis of 166 tibial fractures. Eur J Orthop Surg Traumatol. 2018;28(7):1429-1436. doi:10.1007/s00590-018-2190-2
23) Weng S, Bi C, Gu S, Qi X, Huang Y. Immediate weightbearing after intramedullary fixation of extra-articular distal tibial fractures reduces the nonunion rate compared with traditional weight-bearing protocol: A cohort study. Int J Surg. 2020;76(March):132-135. doi:10.1016/j.ijsu.2020.02.040
24) Gaebler C, Berger U, Schandelmaier P, et al. Rates and odds ratios for complications in closed and open tibial fractures treated with unreamed, small diameter tibial nails: a multicenter analysis of 467 cases. J Orthop Trauma. 2001;15(6):415-423
25) Austin PC, Brunner LJ. Type I error inflation in the presence of a ceiling effect. Am Stat. 2003;57(2):97-104. doi:10.1198/0003130031450