Ahlström A, Westin C, Wikland M, Hardarson T. Prediction of live birth in frozen-thawed single blastocyst transfer cycles by pre-freeze and post-thaw morphology. Hum Reprod. 2013;28:1199– 209.
Bodri D, Sugimoto T, Yao Serna J, Kawachiya S, Kato R, Matsumoto T. Blastocyst collapse is not an independent predictor of reduced live birth: a time-lapse study. Fertil Steril.2016;105:1476-1483.e3.
Campbell A, Fishel S, Bowman N, Duffy S, Sedler M, Fontes C, et al. Modelling a risk classification of aneuploidy in human embryos using non-invasive morphokinetics. Reprod Biomed Online.2013;26:477–85.
Campbell A, Fishel S, Laegdsmand M. Aneuploidy is a key causal factor of delays in blastulation: Author response to “A cautionary note against aneuploidy risk assessment using time-lapse imaging.” Reprod Biomed Online. Reproductive Healthcare Ltd.; 2014;28:279–83.
Capalbo A, Romanelli V, Patassini C, Poli M, Girardi L, Giancani A, Stoppa M, Cimadomo D, Ubaldi FM, Rienzi L. Diagnostic efficacy of blastocoel fluid and spent media as sources of DNA for preimplantation genetic testing in standard clinical conditions. Fertil Steril. 2018;110:870- 879.e5.
Desai N, Goldberg JM, Austin C, Falcone T. Are cleavage anomalies, multinucleation, or specific cell cycle kinetics observed with time-lapse imaging predictive of embryo developmental capacity or ploidy? Fertil Steril. 2018;109:665–74.
Desai N, Ploskonka S, Goodman LR, Austin C, Goldberg J, Falcone T. Analysis of embryo morphokinetics, multinucleation and cleavage anomalies using continuous time-lapse monitoring in blastocyst transfer cycles. Reprod Biol Endocrinol. 2014 20;12:54.
Diez-Juan A, Rubio C, Marin C, Martinez S, Al-Asmar N, Riboldi M, et al. Mitochondrial DNA content as a viability score in human euploid embryos: Less is better. Fertil Steril. 2015;104:534-541.e1.
Fedorcsák P, Dale PO, Storeng R, Ertzeid G, Bjercke S, Oldereid N, Omland AK, Abyholm T, Tanbo T. Impact of overweight and underweight on assisted reproduction treatment. Hum Reprod. 2004 Nov;19(11):2523-8
Fragouli E, Spath K, Alfarawati S, Kaper F, Craig A, Michel CE, et al. Altered Levels of Mitochondrial DNA Are Associated with Female Age, Aneuploidy, and Provide an Independent Measure of Embryonic Implantation Potential. PLoS Genet. 2015;11:1–18.
Franasiak JM, Forman EJ, Hong KH, Werner MD, Upham KM, Treff NR, et al. The nature of aneuploidy with increasing age of the female partner: A review of 15,169 consecutive trophectoderm biopsies evaluated with comprehensive chromosomal screening. Fertil Steril. 2014;101:656-663.e1.
Gardner DK, Lane M, Stevens J, Schlenker T, Schoolcraft WB. Blastocyst score affects implantation and pregnancy outcome: Towards a single blastocyst transfer. Fertil Steril. 2000;73:1155–8.
Goddijn M, Leschot NJ. Genetic aspects of miscarriage. Bailliere’s Best Pract Res Clin Obstet
Gynaecol. 2000;14:855–65.
Hammond ER, Shelling AN, Cree LM. Nuclear and mitochondrial DNA in blastocoele fluid and embryo culture medium: Evidence and potential clinical use. Hum Reprod. 2016;31:1653–61.
Hara T, Kin A, Aoki S, Nakamura S, Shirasuna K, Kuwayama T, et al. Resveratrol enhances the clearance of mitochondrial damage by vitrification and improves the development of vitrifiedwarmed bovine embryos. PLoS One. 2018;13:1–17.
Hashimoto S, Morimoto N, Yamanaka M, Matsumoto H, Yamochi T, Goto H, et al. Quantitative and qualitative changes of mitochondria in human preimplantation embryos. J Assist Reprod Genet. Journal of Assisted Reproduction and Genetics; 2017;34:573–80.
Hayashi M, Satoh S, Matsuda Y, Nakai A. The effect of single embryo transfer on perinatal outcomes in Japan. Int J Med Sci. 2015;12:57–62.
Ichikawa K, Shibahara H, Shirasuna K, Kuwayama T, Iwata H. Cell-free DNA content in follicular fluid: A marker for the developmental ability of porcine oocytes. Reprod Med Biol. 2020;19:95–103.
Irani M, Neill CO, Palermo GD, Ph D, Xu K, Ph D. Blastocyst development rate in fluences implantation and live birth rates of similarly graded euploid blastocysts. Fertil Steril. 2018;110:95-102.e1.
Ishihara O, Jwa SC, Kuwahara A, Katagiri Y, Kuwabara Y, Hamatani T. Assisted reproductive technology in Japan: A summary report for 2017 by the Ethics Committee of the Japan Society of Obstetrics and Gynecology. Reprod Med Biol. 2020;19:3–12.
Kansaku K, Munakata Y, Shirasuna K, Kuwayama T, Iwata H. Mitochondrial cell-free DNA secreted from porcine granulosa cells. Zygote. 2019;27:272–8.
Kato K, Ezoe K, Yabuuchi A, Fukuda J, Kuroda T, Ueno S, et al. Comparison of pregnancy outcomes following fresh and electively frozen single blastocyst transfer in natural cycle and clomiphene-stimulated IVF cycles. Hum Reprod Open. 2018;2018:1–8.
Kim J, Seli E. Mitochondria as a biomarker for IVF outcome. Reproduction. 2019;157(6): 235- 242.
Kobayashi M, Ito J, Shirasuna K, Kuwayama T, Iwata H. Comparative analysis of cell-free DNA content in culture medium and mitochondrial DNA copy number in porcine parthenogenetically activated embryos. J Reprod Dev. 2020;10.1262/jrd.2020-097.
Kobayashi M, Kobayashi J, Shirasuna K, Iwata H. Abundance of cell-free mitochondrial DNA in spent culture medium associated with morphokinetics and blastocyst collapse of expanded blastocysts. Reprod Med Biol. 2020;404–14.
Leese HJ. Metabolism of the preimplantation embryo: 40 years on. Reproduction. 2012;143(4): 417-27.
Ligon S, Lustik M, Levy G, Pier B, D M. Low antimüllerian hormone (AMH) is associated with decreased live birth after in vitro fertilization when follicle-stimulating hormone and AMH are discordant. Fertil Steril. 2015;112:73-81.e1.
Liu Y, Shen Q, Zhao X, Zou M, Shao S, Li J, et al. Cell-free mitochondrial DNA in human follicular fluid: A promising bio-marker of blastocyst developmental potential in women undergoing assisted reproductive technology. Reprod Biol Endocrinol. Reproductive Biology and Endocrinology; 2019;17:1–9.
Marcos J, Pérez-Albalá S, Mifsud A, Molla M, Landeras J, Meseguer M. Collapse of blastocysts is strongly related to lower implantation success: A time-lapse study. Hum Reprod. 2015;30:2501–8.
Minasi MG, Colasante A, Riccio T, Ruberti A, Casciani V, Scarselli F, et al. Correlation between aneuploidy, standard morphology evaluation and morphokinetic development in 1730 biopsied blastocysts: A consecutive case series study. Hum Reprod. 2016; 31:2245–54
Mumusoglu S, Yarali I, Bozdag G, Ozdemir P, Polat M, Sokmensuer LK, et al. Time-lapse morphokinetic assessment has low to moderate ability to predict euploidy when patient– and ovarian stimulation–related factors are taken into account with the use of clustered data analysis. Fertil Steril. 2017;107:413-421.e4.
Nagata S, Tatematsu K, Kansaku K, Inoue Y, Kobayashi M, Shirasuna K, Iwata H. Effect of aging on mitochondria and metabolism of bovine granulosa cells. J Reprod Dev. 2020; 10.1262/jrd.2020-071.
Niimura S. Time-lapse videomicrographic analyses of contractions in mouse blastocysts. J Reprod Dev. 2003;49:413–23.
Papanikolaou EG, Kolibianakis EM, Tournaye H, Venetis CA, Fatemi H, Tarlatzis B, et al. Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis. Hum Reprod. 2008;23:91–9.
Pribenszky C, Nilselid AM, Montag M. Time-lapse culture with morphokinetic embryo selection improves pregnancy and live birth chances and reduces early pregnancy loss: a meta-analysis.
Reprod Biomed Online. 2017;35:511–20.
Reignier A, Lammers J, Barriere P, Freour T. Can time-lapse parameters predict embryo ploidy? A systematic review. Reprod Biomed Online. 2018;36:380–7.
Reynier P, May-Panloup P, Chrétien MF, Morgan CJ, Jean M, Savagner F, et al. Mitochondrial DNA content affects the fertilizability of human oocytes. Mol Hum Reprod. 2001;7:425–9.
Roque M, Lattes K, Serra S, Solà I, Geber S, Carreras R, et al. Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: A systematic review and meta-analysis. Fertil Steril. 2013;99:156–62.
Schoolcraft WB, Gardner DK, Lane M, Schlenker T, Hamilton F, Meldrum DR. Blastocyst culture and transfer: Analysis of results and parameters affecting outcome in two in vitro fertilization programs. Fertil Steril. 1999;72:604–9.
Sciorio R, Thong KJ, Pickering SJ. Spontaneous blastocyst collapse as an embryo marker of low pregnancy outcome: A time-lapse study. J Bras Reprod Assist. 2020;24:34–40.
Simon AL, Kiehl M, Sc M, Fischer E, Proctor JG. Pregnancy outcomes from more than 1,800 in vitro fertilization cycles with the use of 24-chromosome single-nucleotide polymorphism – based preimplantation genetic testing for aneuploidy. Fertil Steril. 2018;110:113–21.
Stigliani S, Persico L, Lagazio C, Anserini P, Venturini PL, Scaruffi P. Mitochondrial DNA in Day 3 embryo culture medium is a novel, non-invasive biomarker of blastocyst potential and implantation outcome. Mol Hum Reprod. 2014;20:1238–46.
Stigliani S, Orlando G, Massarotti C, Casciano I, Bovis F, Anserini P, Ubaldi FM, Remorgida V, Rienzi L, Scaruffi P. Non-invasive mitochondrial DNA quantification on day 3 predicts blastocyst development: a prospective, blinded, multi-centric study. Mol Hum Reprod. 2019; 25:527–37.
Storr A, Venetis CA, Cooke S, Kilani S, Ledger W. Inter-observer and intra-observer agreement between embryologists during selection of a single Day 5 embryo for transfer: A multicenter study. Hum Reprod. 2017;32:307–14.
Thompson SM, Onwubalili N, Brown K, Jindal SK, McGovern PG. Blastocyst expansion score and trophectoderm morphology strongly predict successful clinical pregnancy and live birth following elective single embryo blastocyst transfer (eSET): A national study. J Assist Reprod Genet. 2013;30:1577–81.
Treff NR, Fedick A, Tao X, Devkota B, Taylor D, Scott RT. Evaluation of targeted nextgeneration sequencing-based preimplantation genetic diagnosis of monogenic disease. Fertil Steril. 2013;99:1377-1384.e6.
Victor AR, Brake AJ, Tyndall JC, Griffin DK, Zouves CG, Barnes FL, et al. Accurate quantitation of mitochondrial DNA reveals uniform levels in human blastocysts irrespective of ploidy, age, or implantation potential. Fertil Steril. 2017;107:34-42.e3.
Xu J, Fang R, Chen L, Chen D, Xiao JP, Yang W, et al. Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization. Proc Natl Acad Sci U S A. 2016;113:11907–12.
Yang ST, Shi JX, Gong F, Zhang SP, Lu CF, Tan K, et al. Cleavage pattern predicts developmental potential of day 3 human embryos produced by IVF. Reprod Biomed Online. 2015;30:625–34.
Zeng HT, Ren Z, Yeung WSB, Shu YM, Xu YW, Zhuang GL, et al. Low mitochondrial DNA and ATP contents contribute to the absence of birefringent spindle imaged with PolScope in in vitro matured human oocytes. Hum Reprod. 2007;22:1681–6.
Zhu D, Zhang J, Cao S, Zhang J, Heng BC, Huang M, et al. Vitrified-warmed blastocyst transfer cycles yield higher pregnancy and implantation rates compared with fresh blastocyst transfer cycles - Time for a new embryo transfer strategy? Fertil Steril. 2011;95:1691–5.