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The age-specific normative values of standing whole-body sagittal alignment parameters in healthy adults: based on international multicenter data

Ouchida, Jun Nakashima, Hiroaki Kanemura, Tokumi Okamoto, Masashi Hatsushikano, Shun Imagama, Shiro Le Huec, Jean Charles Hasegawa, Kazuhiro 名古屋大学

2023.02

概要

Sagittal alignment of the spine is widely recognized as a primary subject for preoperative ...

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参考文献

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21

Whole Body Sagittal Alignment

Figure legends

Vertical line

ODUpper TK

(T1-4)

Cr-

Global TK

(T1-12)

O-C2 angle

Lower TK

(T4-12)

Global LL (L1-S1)

SVA

C2-7 lordotic angle

Lower LL (L4-S1)

SSA

T1-slope

CAM-HA

TPA

SS

PI

KF

PT

Pelvic thickness

Figure 1. Spinopelvic parameters and whole body sagittal alignment parameters

22

Whole Body Sagittal Alignment

Table 1. Baseline characteristics of healthy subjects from the three cohorts

Total Sample

Mean

SD

317

Characteristics

No. of subjects

Race

Age (years)

Female, n (%)

ODI score

Cohort 1

Mean

SD

106

Mongoloid

52.6

12.3

76 (71.7)

8.0

7.4

43.8

14.7

192 (60.6)

4.3

6.2

Cohort 2

Mean

SD

100

Mongoloid

39.4

12.1

63 (63.0)

4.3

5.4

Cohort 3

Mean

SD

111

Caucasian

39.2

15.2

53 (47.7)

0.7

2.2

Table 2. The mean and standard deviation of all measured parameters according to age group

Total

Mean

15.9

1.3

22.7

11.1

33.6

40.5

11.3

35.2

54.1

38.2

12.6

50.8

10.8

-0.8

-0.2

-9.9

-1.7

-2.1

8.0

129.1

2.1

4.3

O-C2 angle (°)

C2-7 lordotic angle (°)

T1-slope (°)

Upper (T1-4) TK (°)

Lower (T4-12) TK (°)

Global (T1-12) TK (°)

Upper (L1-3) LL (°)

Lower (L4-S1) LL (°)

Global(L1-S1) LL (°)

SS (°)

PT (°)

PI (°)

Pelvic thickness (cm)

Knee flexion (°)

SVA (cm)

OD-HA (°)

Cr-HA (cm)

CAM-HA (cm)

TPA (°)

SSA (°)

CrSVA (cm)

ODI score

Male

SD

8.1

12.6

8.4

6.3

10.5

10.8

10.5

7.1

11.5

8.4

7.6

10.9

0.9

5.5

2.6

20.6

2.9

3.0

7.6

17.2

2.6

6.2

Total (n=125)

Mean

SD

15.6

7.6

3.8

12.0

24.9

8.4

13.0

6.6

35.2

10.4

43.5

11.4

11.8

10.5

36.4

6.1

55.1

11.8

38.1

8.9

11.4

6.8

49.6

10.4

10.6

1.0

0.5

4.8

-0.5

2.4

-10.1

20.4

-1.7

2.8

-2.2

3.0

6.7

6.2

130.5

8.0

1.8

2.4

2.8

4.5

20s-30s (n=62)

Mean

SD

15.3

6.6

1.2

10.1

23.8

7.1

12.6

6.1

35.2

9.1

43.1

9.1

13.3

10.4

37.4

5.4

56.6

10.3

38.9

8.4

10.2

6.2

49.1

10.4

10.6

0.8

-1.7

4.5

-1.0

2.1

-12.7

23.3

-2.2

2.4

-2.6

2.7

5.7

6.0

131.6

7.7

1.6

1.8

1.7

3.8

40s-50s (n=45)

Mean

SD

16.3

8.1

4.0

12.6

24.7

9.5

12.5

7.1

34.5

11.7

42.2

13.4

11.1

10.1

35.1

6.9

54.5

12.3

37.9

9.6

13.0

7.6

50.8

10.7

10.6

0.8

2.1

4.1

-0.3

2.2

-8.5

17.1

-1.5

2.7

-2.2

2.6

7.8

6.7

130.4

8.4

1.8

2.5

3.6

4.7

≥60s (n=18)

Mean

SD

14.8

9.8

12.1

13.5

29.4

8.8

15.4

6.9

37.1

11.4

48.0

12.4

8.1

11.0

36.4

6.4

51.4

14.7

36.4

9.1

11.9

6.6

48.1

9.5

10.9

1.9

3.8

4.2

0.7

3.1

-5.0

16.2

-0.7

4.1

-0.8

4.6

7.7

5.0

127.2

7.7

2.5

3.9

4.4

5.3

Total (n=192)

Mean

SD

16.1

8.4

-0.4

12.8

21.3

8.1

9.8

5.8

32.5

10.5

38.6

10.0

11.0

10.6

34.4

7.6

53.4

11.3

38.2

8.1

13.4

8.0

51.6

11.2

10.8

0.7

-1.6

5.7

-0.1

2.8

-9.9

20.8

-1.7

2.9

-2.1

3.0

8.8

8.2

128.1

21.1

2.2

2.7

5.3

6.9

Female

20s-30s (n=74)

40s-50s (n=84)

Mean

SD

Mean

SD

17.1

9.9

15.6

7.3

-3.7

12.7

-1.2

10.8

19.5

6.8

20.9

7.9

10.7

4.8

9.7

5.9

31.3

9.1

30.3

9.6

38.5

8.7

36.5

10.3

11.9

9.6

10.6

10.8

36.0

7.1

32.7

7.3

55.5

10.1

52.1

12.2

38.2

8.0

38.3

8.4

10.4

6.8

14.8

7.8

48.7

10.1

53.1

12.0

11.1

0.7

10.8

0.7

-4.5

5.5

-0.5

4.3

-1.5

1.9

0.3

2.3

-15.2

23.6

-6.2

16.5

-2.5

2.7

-1.5

2.4

-2.9

2.8

-1.9

2.6

5.1

6.3

10.2

7.9

131.5

8.5

129.4

8.1

1.4

1.8

2.3

2.4

2.2

4.3

6.9

7.2

≥60s (n=34)

Mean

SD

15.2

7.8

8.8

13.7

25.9

9.8

8.1

7.1

40.5

12.0

43.9

10.2

9.9

12.1

35.1

8.9

52.1

11.2

37.6

7.6

16.4

9.2

54.0

10.3

10.5

0.7

1.8

6.3

2.2

3.6

-7.2

22.0

-0.1

3.7

-0.6

3.6

13.2

9.6

117.5

45.9

4.0

3.8

8.1

8.3

Table 3. Correlation between age and whole body sagittal alignment parameters

Male

Female

Male

Female

O-C2 angle

C2-7 lordotic angle

T1-slope

Upper TK (T1-4)

.020

.326

.242

.152

.055

.147

.822

.000

.007

.091

.543

.103

.065

.105

-.108

.355

.279

-.163

.244

.137

-.062

-.061

.137

.000

.000

.024

.001

.058

.396

.401

PI

Pelvic thickness

KneeFlex

SVA

OD-HA

Cr-HA

CAM-HA

-.020

.062

.427

.234

.120

.163

.149

.824

.491

.000

.009

.182

.072

.236

-.316

.429

.507

.161

.001

.000

.000

.000

.026

Lower TK (T4-12) Global TK (T1-12)

Upper LL (L1-3)

SS

PT

-.155

.176

.043

.084

.050

-.139

-.031

.357

.054

.672

.000

TPA

SSA

CrSVA

ODI score

.169

-.233

.117

.241

.098

.060

.009

.198

.007

.275

.262

.442

-.173

.349

.302

.000

.000

.000

.016

.000

.000

-.166

Lower LL (L4-S1) Global LL (L1-S1)

-.146

-.181

10

23

Whole Body Sagittal Alignment

Table 4. Correlation among whole body sagittal alignment parameters

O-C2

angle

C2-7 lordotic angle

T1-slope

Upper TK (T1-4)

Lower TK (T4-12)

Global TK (T1-12)

Upper LL (L1-3)

Lower LL (L4-S1)

Global LL (L1-S1)

SS

PT

PI

Pelvic thickness

Knee flexion

SVA

OD-HA

Cr-HA

CAM-HA

TPA

SSA

CrSVA

C2-7

lordotic

angle

T1-slope

Global

Upper TK Lower TK

TK (T1(T1-4)

(T4-12)

12)

Upper LL Lower LL Global LL

(L1-3)

(L4-S1)

(L1-S1)

-.470

.000

-.061

.280

.008

.658

.000

.241

.513

.881

-.107

.057

.000

.493

.000

.000

.627

.000

-.042

.457

-.100

.075

-.137

.015

-.072

.198

.582

.000

.136

.016

.126

.024

.800

.000

-.092

.103

.073

.193

.392

.000

-.103

.068

-.051

.363

.833

.000

.284

.000

.305

.000

.242

.000

.277

.000

.038

.505

SS

PT

PI

Pelvic

thickness

Average

Knee

flexion

very weak 0.00-0.19

weak

0.20-0.39

moderate 0.40-0.59

strong 0.60-0.79

very strong

0.80-

-.099

.045

.000

-.016

.431

.407

.649

.538

.080

-.024

.664

-.052

.429

-.064

.257

.162

.996

-.071

.210

.059

.770

.012

.832

-.093

.000

.126

.025

-.051

.000

.116

.040

-.070

.000

.444

.000

.049

.000

.426

.000

-.244

.817

.000

-.153

-.082

.355

-.056

.004

.066

.292

-.012

.097

-.057

.366

.063

.211

.041

.381

.378

.000

.158

.006

.525

.144

.714

.638

.319

.102

.069

.242

-.162

.004

.831

-.024

.670

.309

.110

.051

.261

-.120

.032

.463

-.068

.225

.000

-.227

.000

.005

-.205

.000

.000

-.306

.000

.000

-.319

.000

.000

-.213

.000

-.399

.000

-.048

.398

.177

.002

.228

.000

.057

.313

.064

.254

.075

.180

-.140

.012

-.116

.039

-.155

.006

-.068

.225

.198

.000

.087

.124

-.080

.156

-.037

.517

.131

.019

.347

.000

-.092

.103

.433

.000

.270

.000

-.091

.107

.149

.008

.189

.001

.016

.773

.078

.163

.040

.476

-.074

.187

-.414

.000

-.286

.000

-.209

.000

-.230

.000

-.183

.001

.018

.749

-.005

.924

.342

.000

-.077

.172

.255

.000

-.058

.301

-.136

.015

.056

.320

.327

.000

.247

.000

.136

.016

.091

.109

.411

.000

.016

.778

.191

.001

.141

.012

-.188

.001

-.101

.074

-.136

.016

.048

.396

-.156

.006

-.073

.199

-.058

.307

.306

.000

.170

.002

-.052

.074

.192

.221

.438

.000

.166

.037

.515

-.128

.217

.000

.014

.168

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24

...

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