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6. Life Science and Medical Science

京都大学

2022.07

概要

Several types of accelerator-based irradiation system for boron neutron capture therapy (BNCT) are under de- velopment at present. But, there are a number of subjects, which should be improved for the further advance and generalization of BNCT.

In the viewpoints of medical physics and engineering, the advance for dose estimation is one of the important subjects. For the characterization of irradiation field, quality assurance and quality control (QA/QC), clinical irradiation to actual patient, and so on, an ultimate goal is to perform the three-dimensional and real-time dose es- timation in discriminating for thermal, epi-thermal and fast neutron doses, gamma-ray dose, and boron dose, with simplicity and low effort. Considering about this ultimate dose estimation, several kinds of dose estimation method are studied. It is so difficult to realize the ultimate dose estimation using only one method, but it is neces- sary to use simultaneously more than two methods.

The purposes of this project research are the advance for various dose estimation methods, and the establish- ment of an integrated system for dose estimation in BNCT.

In the second year of this research project, 2021, the advancement for the respective dose estimation methods were forwarded mainly using Heavy Water Neutron Irra- diation Facility (HWNIF) and E-3 Neutron Guide Tube (E-3) at KUR. The integrated system was considered for the simultaneous usage of several dose estimation meth- ods, same as the previous year.

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