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Cytoreductive Surgery and Hyperthermic Chemotherapy for Intrathoracic Pseudomyxoma Peritonei.

KAWAGUCHI Yo 0000-0002-7828-4635 HANAOKA Jun 00452243 0000-0002-5272-556X 滋賀医科大学

2020.06.15

概要

Dissemination of pseudomyxoma peritonei into the thoracic cavity is rare and carries a poor prognosis. Optimal treatment has not been defined. In our institution, patients had received cytoreductive surgery with hyperthermic intrathoracic chemotherapy, which demonstrated good prognosis. A 51-year-old woman was referred to our hospital with right intrathoracic dissemination of pseudomyxoma peritonei. We performed parietal and mediastinal pleurectomy and simple resection of all visible tumors on the diaphragm and visceral pleura, followed by hyperthermic intrathoracic chemotherapy with 20 mg mitomycin at 42-43ºC. The patient had no evidence of disease progression in the thoracic cavity 1 year after surgery.

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参考文献

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patients with pseudomyxoma peritonei syndrome. Ann Surg Oncol 2000; 7: 199-203.

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Kawaguchi Y, Hanaoka J, Ohshio Y et al. Patient Survival after Surgical Management in

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Miner TJ, Shia J, Jaques DP et al. Long-term survival following treatment of

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Yonemura Y, Canbay E, Sako S et al. Pharmacokinetics of docetaxel during

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Figure legends

Fig 1. (A) Computed tomography shows diffuse masses along the pleura. (B) Magnetic

resonance imaging reveals high intensity T2 masses.

Fig 2. (A) Thoracoscope under local anesthesia shows multiple masses on the parietal and

visceral pleura. (B) Visible tumors in the thoracic cavity completely resected by cytoreductive

surgery.

...

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