1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
21.
22.
23.
24.
25.
26.
Global Status Report on Road Safety 2018. Available online: http://apps.who.int/iris/bitstream/handle/10665/277370/WHONMH-NVI-18.20-eng.pdf?ua=1 (accessed on 23 August 2021).
Nagata, I.; Abe, T.; Uchida, M.; Saitoh, D.; Tamiya, N. Ten-year inhospital mortality trends for patients with trauma in Japan:
A multicentre observational study. BMJ Open 2018, 8, e018635. [CrossRef] [PubMed]
Hondo, K.; Shiraishi, A.; Fujie, S.; Saitoh, D.; Otomo, Y. In-hospital trauma mortality has decreased in Japan possibly due to
trauma education. J. Am. Coll. Surg. 2013, 217, 850–857. [CrossRef] [PubMed]
Moore, L.; Turgeon, A.F.; Lauzier, F.; Emond, M. Evolution of patient outcomes over 14 years in a mature, inclusive Canadian
trauma system. World J. Surg. 2015, 39, 1397–1405. [CrossRef]
Ishii, W.; Hitosugi, M.; Takeda, A.; Baba, M.; Iizuka, R. Factors influencing vehicle passenger fatality have changed over 10 years:
A nationwide hospital-based study. Sci. Rep. 2020, 10, 3316. [CrossRef]
Statistics of Japan; e-Stat is a Portal Site for Japanese Government Statistics. Available online: https://www.e-stat.go.jp/en/statsearch/files?page=1&layout=datalist&toukei=00450011&tstat=000001028897&cycle=7&year=19890&month=0&tclass1=00000
1053058&tclass2=000001053061&tclass3=000001053072&result_back=1&tclass4val=0 (accessed on 28 June 2021).
Ministry of Health. Labour and Welfare. Available online: https://www.mhlw.go.jp/toukei/saikin/hw/jinkou/geppo/nengai2
0/index.html (accessed on 13 August 2021).
Traffic Safety Measures in Japan. Available online: https://www.mlit.go.jp/road/management-e/e_pdf/0403_5.pdf (accessed
on 6 August 2021).
Cabinet Office, Government of Japan. Basic Traffic Safety Plan. Available online: https://www8.cao.go.jp/koutu/kihon/
keikaku11/pdf/kihon_keikaku.pdf (accessed on 23 August 2021).
Cabinet Office, Government of Japan. Basic Traffic Safety Plan. Available online: https://www8.cao.go.jp/koutu/taisaku/r0
2kou_haku/zenbun/genkyo/feature/feature_01_2.html (accessed on 23 August 2021).
Kahani, A.T.; Shariat-Mohaymany, A.; Ranjbari, A. Analysis of factors associated with traffic injury severity on rural roads in Iran.
J. Inj. Violence Res. 2012, 4, 36–41. [CrossRef]
Chang, L.Y.; Wang, H.W. Analysis of traffic injury severity: An application of non-parametric classification tree techniques. Accid.
Anal. Prev. 2006, 38, 1019–1027. [CrossRef] [PubMed]
Yan, X.; Radwan, E. Analyses of rear-end crashes based on classification tree models. Traffic Inj. Prev. 2006, 7, 276–282. [CrossRef]
[PubMed]
Durbin, D.R.; Hoffman, B.D. Child passenger safety. Pediatrics 2018, 142, e20182461. [CrossRef] [PubMed]
Evans, S.L.; Nance, M.L.; Arbogast, K.B. Passenger compartment intrusion as a predictor of significant injury for children in
motor vehicle crashes. J. Trauma 2009, 66, 504–507. [CrossRef] [PubMed]
Abe, T.; Oda, J.; Kimura, A.; Sakamoto, Y.; Shiraishi, A.; Tanaka, K.; Tohira, H.; Nakahara, S.; Hayashi, M.; Masuno, T.; et al. Japan
Trauma Date Bank Report 2020. Available online: https://www.jtcr-jatec.org/traumabank/dataroom/data/JTDB2020e.pdf
(accessed on 23 August 2020).
Japan Trauma Care and Research. Japan Trauma Data Bank Annual Report 2011–2015. Available online: http//www.jtcrjatec.
org/traumabank/dataroom/date/JTDB2016.pdf (accessed on 27 June 2020).
Yumoto, T.; Mitsuhashi, T.; Yamakawa, Y.; Iida, A.; Nosaka, N.; Tsukahara, K.; Naito, H.; Nakao, A. Impact of Cushing’s sign
in the prehospital setting on predicting the need for immediate neurosurgical intervention in trauma patients: A nationwide
retrospective observational study. Scand. J. Trauma Resusc. Emerg. Med. 2016, 24, 147. [CrossRef]
Japan Trauma Care and Research. Japan Trauma Datebank. Available online: https//www.jtcr-jatec.org/traumabank/index.htm
(accessed on 27 June 2021).
Zeedyk, M.S.; Wallace, L.; Carcary, B.; Jones, K.; Larter, K. Children and road safety: Increasing knowledge does not improve
behaviour. Br. J. Educ. Psychol. 2001, 71, 573–594. [CrossRef] [PubMed]
Tiwari, G. Progress in pedestrian safety research. Int. J. Inj. Control. Saf. Promot. 2020, 27, 35–43. [CrossRef]
Alonso, F.; Esteban, C.; Tortosa, F.; Useche, S. Perception of Road Safety in Children’s Environment. Am. J. Educ. Res.
2017, 5, 273–278. [CrossRef]
Casado-Sanz, N.; Guirao, B.; Gálvez-Pérez, D. Population ageing and rural road accidents: Analysis of accident severity in traffic
crashes with older pedestrians on Spanish crosstown roads. Res. Transp. Bus. Manag. 2019, 30, 100377. [CrossRef]
Boufous, S.; Finch, C.; Hayen, A.; Williamson, A. The impact of environmental, vehicle and driver characteristics on injury
severity in older drivers hospitalized as a result of a traffic crash. J. Saf. Res. 2008, 39, 65–72. [CrossRef] [PubMed]
Toida, C.; Muguruma, T.; Gakumazawa, M. Ten-year in-hospital mortality trends among paediatric injured patients in Japan: A
nationwide observational study. Clin. Med. 2020, 9, 3273. [CrossRef] [PubMed]
Takahashi, H.; Fujita, T.; Nakahara, S.; Sakamoto, T. Seating position and patterns of severely injured body parts among child
passengers in motor vehicle crashes: Japan as a distinct case. Int. J. Inj. Contr. Saf. Promot. 2018, 25, 427–432. [CrossRef] [PubMed]
Healthcare 2021, 9, 1431
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
10 of 10
World Health Organization. Neurological Disorders: Public Health Challenges; World Health Organization: Geneva, Switzerland,
2006; p. 164.
Kojima, M.; Endo, A.; Shiraishi, A.; Otomo, Y. Age-related characteristics and outcomes for patients with severe trauma: Analysis
of Japan’s nationwide trauma registry. Ann. Emerg. Med. 2019, 73, 281–290. [CrossRef]
Dewan, M.C.; Mummareddy, N.; Wellons, J.C.; Bonfield, C.M. Epidemiology of global pediatric traumatic brain injury: Qualitative
review. World Neurosurg. 2016, 91, 497–509.e1. [CrossRef]
Taylor, C.A.; Bell, J.M.; Breiding, M.J.; Xu, L. Traumatic brain injury-related emergency department visits, hospitalizations, and
deaths—United States, 2007 and 2013. MMWR Surveill. Summ. 2017, 66, 1–16. [CrossRef] [PubMed]
Lichte, P.; Andruszkow, H.; Kappe, M.; Horst, K.; Pishnamaz, M.; Hildebrand, F.; Lefering, R.; Pape, H.C.; Kobbe, P. Increased
in-hospital mortality following severe head injury in young children: Results from a nationwide trauma registry. Eur. J. Med. Res.
2015, 20, 65. [CrossRef] [PubMed]
Mitchell, R.J.; Curtis, K.; Foster, K. A 10-year review of child injury hospitalisations, health outcomes and treatment costs in
Australia. Inj. Prev. 2018, 24, 344–350. [CrossRef]
Rebecca, M.; Kate, C.; Shanley, C.; Andrew, H.; Soundappan, S.; Kellie, W.; Daniel, C. Comparative analysis of trends in paediatric
trauma outcomes in New South Wales, Australia. Injury 2013, 44, 97–103. [CrossRef]
Tesfay, K.; Assefa, M.; Zenebe, D.; Gebremicael, M.; Kebede, G.; Gebrekirstos, H. Road traffic injured patients with severe GCS
and organ injury had a poor prognosis: A retrospective cohort study. BMC Public Health 2019, 19, 749. [CrossRef] [PubMed]
Centers for Disease Control and Prevention. Injury Prevention and Control: Motor Vehicle Safety. Available online:
https://www.cdc.gov/transportationsafety/child_passenger_safety/cps-factsheet.html?CDC_AA_refVal=https%3A%2F%
2Fwww.cdc.gov%2Fmotorvehiclesafety%2Fchild_passenger_safety%2Fcps-factsheet.html (accessed on 13 October 2021).
Diana, D.; Corinne, P.; Florin, J.; Erika-Andrada, B. Safety seat and seat belt use among child motor vehicle occupants, Cluj-Napoca,
Romania. Inj. Prev. 2020, 26, 18–23. [CrossRef]
Burda, J.E.; Sofroniew, M.V. Reactive gliosis and the multicellular response to CNS damage and disease. Neuron 2014, 81, 229–248.
[CrossRef]
Nahmani, M.; Turrigiano, G.G. Adult cortical plasticity following injury: Recapitulation of critical period mechanisms? Neuroscience 2014, 283, 4–16. [CrossRef]
Purcell, N.; Reiss, R.; Eaton, J.; Kumwenda, K.; Quinsey, C.; Charles, A. Survival and Functional Outcomes at Discharge After
Traumatic Brain Injury in Children versus Adults in Resource-Poor Setting. World Neurosurg. 2020, 137, e597–e602. [CrossRef]
Luerssen, T.G.; Klauber, M.R.; Marshall, L.F. Outcome from head injury related to patient’age: A longitudinal prospective study
of adult and pediatric head injury. J. Neurosurg. 1988, 68, 409–416. [CrossRef]
Emami, P.; Czorlich, P.; Fritzsche, F.S.; Westphal, M.; Rueger, J.M.; Lefering, R.; Hoffmann, M. Impact of Glasgow Coma Scale
score and pupil parameters on mortality rate and outcome in pediatric and adult severe traumatic brain injury: A retrospective,
multicenter cohort study. J. Neurosurg. 2017, 126, 760–767. [CrossRef]
Ghajar, J.; Hariri, R.J. Management of pediatric head injury. Pediatr. Clin. North. Am. 1992, 39, 1093–1125. [CrossRef]
Nudo, R.J. Recovery after brain injury: Mechanisms and principles. Front. Hum. Neurosci. 2013, 7, 887. [CrossRef]
Su, Y.R.S.; Veeravagu, A.; Grant, G. Neuroplasticity after traumatic brain injury. In Translational Research in Traumatic Brain Injury;
Laskowitz, D., Grant, G., Eds.; CRC Press/Taylor and Francis Group: Boca Raton, FL, USA, 2016; Chapter 8. [PubMed]
Sauber-Schatz, E.K.; West, B.A.; Bergen, G. Vital signs: Restraint use and motor vehicle occupant death rates among children aged
0-12 years- United States, 2002–2011. MMWR Morb. Mortal. Wkly. Rep. 2014, 63, 113–118. [PubMed]
Berg, M.D.; Cook, L.; Corneli, H.M.; Vernon, D.D.; Dean, J.M. Effect of seating position and restraint use on injuries to children in
motor vehicle crashes. Pediatrics 2000, 105, 831–835. [CrossRef] [PubMed]
Lennon, A.; Siskind, V.; Haworth, N. Rear seat safer: Seating position, restraint use and injuries in children in traffic crashes in
Victoria, Australia. Accid. Anal. Prev. 2008, 40, 829–834. [CrossRef]
Durbin, D.R.; Arbogast, K.B.; Mol, E.K. Seat belt syndrome in children: A case report and review of the literature. Pediatr. Emerg.
Care 2001, 17, 474–477. [CrossRef] [PubMed]
Sauber-Schatz, E.K.; Thomas, A.M.; Cook, L.J. Motor vehicle crashes, medical outcomes, and hospital charges among children
aged 1–12 years-crash outcome data evaluation system, 11 states, 2005–2008. MMWR Surveill. Summ. 2015, 64, 1–32. [CrossRef]
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