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Ultrasound Speckle Tracking and Color Doppler Elastography for Quantitative Tissue Assessment

Norma Hermawan 東北大学

2021.09.24

概要

This dissertation describes an implementation of speckle tracking algorithm for quantitative tissue assessment with clinical application in orthopedics for identifying Adhesive Capsulitis (AC) disease, and the method of mechanically induced shear wave elastography with a color Doppler imaging. The implemented speckle tracking software was capable of visualizing layers of tissue in the shoulder based on their velocity during a movement. In addition, Adhesion Index (AdI) quantity was introduced as a novel measure of shoulder adhesion, which was calculated from the velocity difference between subscapularis and the deltoid muscle of the shoulder. The result suggested that motion limitation on the AC patient could be explained by the AdI because the patient with restricted motion encountered a noticeable adhesion on the subscapularis. On the other part, a method of color Doppler elastography by mechanically induced shear wave is implemented. The capability of the method in resolving elasticity map of homogeneous and non- homogeneous phantom is demonstrated. Since it does not need a precise control to the imaging parameter, it can be implemented in standard commercially available ultrasound (US) machines. The measurement results suggested that the accurate estimation of the shear wave velocity was obtained. The merits of speckle tracking and mechanically induced shear wave elastography methods are that quantitative parameters of tissue character are obtained non-invasively and that all measurement data are obtainable by a standard ultrasound machine. Clinical application in the field of orthopedic surgery is desired in near future.

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