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Acknowledgements

The present study benefitted from the support of Yuichi Matsuda, Ryohei Yoshikawa, Yuta Muranaka, Mitsuyo

Okada, Toshimi Doi, Shinichi Shimada, Masashi Kanai, Masato Ogawa, Ryo Yoshihara, Natsumi Ikezawa, Ayami

Osumi, and Ayano Makihara.

Author contributions

K.P.I.: Conceptualization, Methodology, Validation, Formal analysis, Writing—Original Draft; Y.K.: Conceptualization, Methodology, Validation, Formal analysis, Writing—Review & Editing, Visualization; M.K., K.I.,

A.O., I.K.: Conceptualization, Investigation, Writing—Review & Editing; K.N.: Resources, Writing—Review &

Editing, Supervision; K.O., H.N., H.T., D.M., I.S.: Resources, Writing—Review & Editing.

Funding

This work was supported by JSPS KAKENHI Grant Number JP22K11392.

Competing interests The authors declare no competing interests.

Additional information

Correspondence and requests for materials should be addressed to K.P.I.

Reprints and permissions information is available at www.nature.com/reprints.

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and

institutional affiliations.

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