Biofunctional Chemistry Research Section

概要

A transition to renewable energy technologies re­ transition renewable technologies quires quires new chemistry to learn from nature. Nature has chemistry learn nature. has developed fantastic solutions to convert the solar en­ fantastic to the en- ergy to the chemical energy and to utilize them in the to chemical and utilize in exceptionally exceptionally efficient manners for almost 3 billion manners almo t 3 years. years. It is our challenge to understand the efficient bi­ is challenge understand efficient oenergetic oenergetic processes of nature and to construct bio-in- of and construct spired spired energy utilization systems. The research inter­ utilization . research ests ests in our group focus on the design of biomacromol­ our focu on design ecules ecules and their assemblies for molecular recognition, their for recognition catalysis catalysis and signal transduction in water, the solvent signal in , solvent of life. We take synthetic, organic chemical, biochem­ life We synthetic organic , ical ical and biophysical approaches to understand the bi­ biophysical to the ological ological molecular recognition and chemical reactions. recognition chemical Proteins Proteins and protein/nucleic acids assemblies are ex­ protein/nucleic assemblies ex- plored to realize biomimetic function of biological to biomimetic of systems systems, such as visualization of cellular signals by such visualization cellular by fluorescent biosensors, directed self-assembly of pep­ biosensors directed of tides tides and proteins to build up nanobiomaterials, tailor­ proteins build nanobiomaterials tailor- ing artificial receptors and enzymes based on the com­ artificial and based the plex plex of RNA and a peptide or a protein, and reconsti­ RNA a or protein and tution tution of the functional assemblies of receptors and en­ the assembl es and 巧zymes on the nanoarchitectures. Followings are main on nanoarchitectures Followings main research achievements in fiscal year 2021.

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