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Table of contents

Fc region binding peptide conjugated with attenuated lytic peptide L17E trimer

[FcB(L17E)3] was designed for intracellular delivery of IgG. Liquid droplets were formed

by mixing Alexa Fluor 488 labeled IgG (Alexa488-IgG) with FcB(L17E)3. Droplet

contact with cell membrane led to quick influx of Alexa488-IgG throughout cells.

Successful delivery of functional proteins into cells allowed binding to subcellular targets

in the presence of FcB(L17E)3.

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...