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5. Conclusions
Our study demonstrated changes in prescription patterns of AEDs for
the treatment of adult patients with newly diagnosed focal epilepsy in
Japan, found a trend of increased reliance on new AEDs between 2006
and 2017 and a consistently high physician adherence to the Guideline
of Epilepsy Treatment 2010 from 2010 to 2017. Furthermore, our study
also showed that health facilities with 0–19 beds (clinics) were less in
clined to prescribe new AEDs and adhere to established guidelines.
Funding
This study was supported by the Department of Pharmacoepidemi
ology, Kyoto University; Department of Epilepsy, Movement Disorders,
and Physiology, Kyoto University [15H05874]; the Japan Society for the
Promotion of Science (JSPS) [19H03574]; and the Project Promoting
Clinical Trials for Development of New Drugs (grant number:
19lk0201061h0004) from the Japan Agency for Medical Research and
Development (AMED).
Declaration of competing interest
None of the authors have any competing interests to declare.
Acknowledgement
This study is based on data from the JMDC. The interpretation and
conclusions contained herein do not represent those of the JMDC.
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