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Relationship between Physical Activity and Health-related Quality of Life in Hospitalized and Terminally Ill Cancer Patients

Yamaga, Takayoshi Matsumori, Keiji Otsu, Yusuke Nakasone, Saki Koizumi, Tomonobu 信州大学

2020.06.18

概要

Background : The relationship of physical activity (PA) and health-related quality of life (HRQoL) in hospitalized and terminally ill cancer patients has yet to be determined. The present study was performed to evaluate PA status and the relationships between PA and HRQoL outcomes in advanced and hospitalized terminally ill cancer patients.

Materials and Methods : Patients with advanced, and/or metastatic malignancies were eligible. PA had been measured for 1 week using a uniaxial accelerometer and divided into “light” activity level on the best PA over the past week (PA <150 minutes) or “high” activity on the best PA over the past week (PA ≥150 minutes). HRQoL was measured by the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30). In addition, cancer-related symptoms and the ability to perform basic movements and activities of daily living (ADL) were also measured. We examined differences in PA level by binomial logistic and multiple linear regression analyses.

Results : Ninety-seven subjects were enrolled in the study. The high PA group (PA ≥150) had significantly higher HRQoL and increased ability to perform basic movements and ADL. The most important factor associat­ ed with engagement in PA was the ability to perform basic movements.

Conclusion : This study showed that hospitalized and terminally ill cancer patients with PA ≥150 minutes per week had higher HRQoL. Advanced patients in hospitalization presenting with PA ≥150 have the potential for improved HRQoL by palliative rehabilitation. Shinshu Med J 68 : 149―157, 2020

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