書き出し
Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in animal model
概要
A chimeric antigen receptor (CAR) is an artificially generated receptor with a monoclonal antibody-derived singlechain variable fragment (scFv) in its extracellular domain
and CD3z or co-stimulatory molecules in its intracellular
domain (June et al., 2018; Scarfò & Maus, 2017). CAR-T
Akihiro Ishikawa and Masazumi Waseda contributed equally to
this work. ...