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Receptors in Spermatozoa – Their expressions and Functions

HIRADATE Yuki HARA Kenshiro TANEMURA Kentaro 東北大学

2021.03

概要

For stable breeding of livestock, it is necessary to deepen the understanding of sperm having fertility. It is well known that spermatozoa have receptor patterns which are similar to those of nerve cells. Neurotensin (NTS) is initially isolated from hypothalamus, later its multiple functions in several tissues have been elucidated. However, there is still little information about the effects of NTS on the reproductive organs. This paper reviews the mechanism of ligand secretion from the female side as well as the expression of NTS receptors in spermatozoa and their physiological functions. It also describes the contribution of NTS to preimplantation embryo development and focuses on the function of NTS as a cofactor from fertilization to early embryonic development.

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参考文献

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