リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

大学・研究所にある論文を検索できる 「妊娠中に増大した卵巣甲状腺腫の1例」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

コピーが完了しました

URLをコピーしました

論文の公開元へ論文の公開元へ
書き出し

妊娠中に増大した卵巣甲状腺腫の1例

長原, 大二郎 小原, 久典 菊地, 範彦 安藤, 大史 横川, 裕亮 小野, 元紀 田中, 泰裕 竹内, 穂高 山田, 靖 宮本, 強 塩沢, 丹里 信州大学

2020.08.21

概要

Pregnancy complicated with struma ovarii is rare. We report a case of struma ovarii that enlarged during pregnancy. We also immunohistochemically investigated the expression of estrogen receptors (ER), progesterone receptors (PR), and thyroid stimulating hormone receptors (TSHR) in tumor cells to explore the mechanism of lesion enlargement.

A 30-year-old woman was diagnosed with right ovarian mature teratoma 4 cm in diameter using MRI five months before pregnancy. After she became pregnant, transvaginal ultrasonography revealed that the mass size was gradually increased. MRI examination was again performed at 14 weeks of gestation, which showed en- largement of the tumor to 5.5 cm in diameter, however, there was no apparent malignant finding. The clinical diagnosis was mature teratoma or struma ovarii of the right ovary. Laparoscopy-assisted ovarian cystectomy was performed at 15 weeks of gestation, and the pathological diagnosis of the removed tumor was struma ovarii. Immunohistochemical examination of the tumor demonstrated the positive expression of PR, but the expression of ER and TSHR was negative.

In the present case, the size of struma ovarii was increased during pregnancy, and this enlargement may be induced by pregnancy-related hormonal milieu via PR. Shinshu Med J 68 : 189―195, 2020

参考文献

1) 日本産科婦人科学会・日本病理学会:卵巣腫瘍 ・ 卵管癌 ・ 腹膜癌取り扱い規約,病理,第1版,2016

2) 元島成信,熊谷晴介,河村京子,他:卵巣甲状腺腫の画像所見 小倉医療センターにおける11例の検討.医療 72:162-168,2018

3) 藤原道久,近藤佳子,西条仁子,物部泰昌:術前診断を行い得た卵巣甲状腺腫の1例.現代産婦人科 60:425-429,2011

4) Kung AW, Ma JT, Wang C, Young RT : Hyperthyroidism during pregnancy due to coexistence of struma ovarii and Graves’ disease. Postgrad Med J 66 : 132-133, 1990

5) Usta IM, Khoury NG, Khalil AM, Nassar AH : Coexistence of a round ligament dermoid cyst and struma ovarii in pregnancy. Eur J Obstet Gynecol Reprod Biol 126 : 271-272, 2006

6) Guven ES, Dilbaz S, Ilhan AK, Demir OF, Haberal A : Struma ovarii complicating pregnancy. J Obstet Gynaecol 25 : 512-513, 2005

7) Bhanap PL, Kulkarni D : Struma ovarii-an interesting case of ovarian tumor in pregancy. MedPulse-International Medical Journal 1 : 385-388, 2014

8) Oreopulu FV, Sofoudis C, Voulgaridou S, Stasinopoulou S, Fountoulis S, Fragulidis GP : Struma ovarii complicating pregnancy : a case report. Clin Exo Obstet Gynecol 42 : 550-552, 2015

9) Chandresekar HV : Struma ovarii complicating pregnancy-a case report. University Journal of Pre and Para Clinical Sciences 2, 2016

10) Moggian G, Saragoni A, Pellegri E, et al : Struma ovarii : report of a case with malignant evolution and of another observed in the course of pregnancy. Eur J Gynaecol Oncol 1 : 201-202, 1980

11) Sifakis S, Panayiotides IG, Angelakis E, Martavatzis N, Koumantakis E : Benign struma ovarii complicating pregancy : a case report and review of the literature. Arch Gynecol Obstet 269 : 72-73, 2003

12) 村上 功,平尾 健,土光順子,隅田能雄,春日義生,清水和彦:妊娠中に甲状腺機能亢進を呈した卵巣甲状腺腫の一例.栃木産婦人科医報 32:158-160,2006

13) Netters FJ, van Oven MW, van Loon AJ, Hoogenberg K : Struma ovarii during pregnancy. Ned Tijdschr Geneeskd 152 : 1335-1338, 2008

14) Coughlin L, Haddad NG : Struma ovarii presenting as hyperemesis gravidarum in pregancy. J Obstet Gynaecol 20 : 310, 2000

15) Merza Z, White D, Khanem N : Struma Ovarii in Pregnancy : An Uncommon Cause of Hyperthyroidism. Clin Nucl Med 40 : 687-688, 2015

16) 河見貴子,平野浩紀,田中 優,甲斐由佳:脊硬麻下に吊り上げ法で単孔式腹腔鏡下手術を行った卵巣嚢腫合併妊娠の8例.現代産婦人科 64:309-313,2016

17) Mascilini F, Savelli L, Scifo MC, et al : Ovarian masses with papillary projections diagnosed and removed during pregnancy : ultrasound features and histological diagnosis. Ultrasound Obstet Gynecol 50 : 116-123, 2017

18) Khalife D, Nassif J, Nazha B, Khalifeh I, Khoury S, Khalil A : An unusual case of struma ovarii causing ovarian torsion during pregnancy. J Obstet Gynaecol 39 : 716-717, 2019

19) Pepe F, Valenti O, Insalaco G, Zigarelli MMG, Pepe L, Piana M : Struma ovarii complicating pregnancy. Case report and literature review. G Chir 40 : 199-207, 2019

20) Chen D, Qi W, Zhang P, Guan H, Wang L : Expression of the estrogen receptor α, progesterone receptor and epidermal growth factor receptor in papillary thyroid carcinoma tissues. Oncol Lett 10 : 317-320, 2015

21) Sturniolo G, Zafon C, Moleti M, Castellví J, Vermiglio F, Mesa J : Immunohistochemical Expression of Estrogen Receptor-α and Progesterone Receptor in Patients with Papillary Thyroid Cancer. Eur Thyroid J 5 : 224-230, 2016

22) Teale E, Gouldesbrough DR, Peacey SR : Graves’ disease and coexisting struma ovarii : struma expression of thyrotropin receptors and the presence of thyrotropin receptor stimulating antibodies. Thyroid 16 : 791-793, 2006

参考文献をもっと見る

全国の大学の
卒論・修論・学位論文

一発検索!

この論文の関連論文を見る