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Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information

Chen, Ying Sakurai, Kunie Maeda, Sumihiro Masui, Tohru Okano, Hideyuki Dewender, Johannes Seltmann, Stefanie Kurtz, Andreas Masuya, Hiroshi Nakamura, Yukio Sheldon, Michael Schneider, Juliane Stacey, Glyn N. Panina, Yulia Fujibuchi, Wataru 京都大学 DOI:10.1016/j.stemcr.2021.02.014

2021

概要

The past decade has witnessed an extremely rapid increase in the number of newly established stem cell lines. However, due to the lack of a standardized format, data exchange among stem cell line resources has been challenging, and no system can search all stem cell lines across resources worldwide. To solve this problem, we have developed the Integrated Collection of Stem Cell Bank data (ICSCB) (http://icscb.stemcellinformatics.org/), the largest database search portal for stem cell line information, based on the standardized data items and terms of the MIACARM framework. Currently, ICSCB can retrieve >16, 000 cell lines from four major data resources in Europe, Japan, and the United States. ICSCB is automatically updated to provide the latest cell line information, and its integrative search helps users collect cell line information for over 1, 000 diseases, including many rare diseases worldwide, which has been a formidable task, thereby distinguishing itself from other database search portals.

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