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大学・研究所にある論文を検索できる 「Use of Peroral Pancreatoscopy in the Diagnosis of Elusive Intraductal Papillary Mucinous Neoplasm With High-Grade Dysplasia」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

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Use of Peroral Pancreatoscopy in the Diagnosis of Elusive Intraductal Papillary Mucinous Neoplasm With High-Grade Dysplasia

Sarita, Mabel Angela T. Sakai, Arata Tsujimae, Masahiro Kobayashi, Takashi Masuda, Atsuhiro Kanzawa, Maki Toyama, Hirochika Kodama, Yuzo 神戸大学

2023.10

概要

Intraductal papillary mucinous neoplasm (IPMN) is a premalignant lesion of the pancreas that can occasionally manifest as recurrent acute pancreatitis. In this report, we discuss a unique case of a 49-year-old woman who presented with recurrent acute pancreatitis of an unknown cause for several years. Workup using peroral pancreatoscopy eventually showed main-duct IPMN with high-grade dysplasia as the obscure cause of recurrent acute pancreatitis. This case report highlights the clinical course of main-duct IPMN and the evolving role of peroral pancreatoscopy in patients with recurrent acute pancreatitis.

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It must be noted that POPS has a 12% adverse event rate, with

mild post-ERCP pancreatitis being the most common.7 Judicious use of POPS in the workup of IPMN should always be

practiced bearing in mind its risks and benefits. In current

clinical practice, the exact role of POPS in patients with RAP

and IPMN remains to be determined.6

In conclusion, IPMN with high-grade dysplasia may be a

cause of recurrent acute pancreatitis. This case report showed

how the use of POPS aided in early diagnosis in patients with

equivocal findings in other imaging tests. The role of direct

visualization with POPS in patients with RAP or IPMN

should be determined in future studies because it may alter

the patient’s prognosis. The procedures followed were in

accordance with the Declaration of Helsinki of the World

Medical Association.

ACG Case Reports Journal / Volume 10

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Copyright: ª 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of

The American College of Gastroenterology. This is an open-access article distributed

under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives

License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work,

provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

acgcasereports.com 4

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