リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

大学・研究所にある論文を検索できる 「Effects of Mobilization within 72 h of ICU Admission in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

コピーが完了しました

URLをコピーしました

論文の公開元へ論文の公開元へ
書き出し

Effects of Mobilization within 72 h of ICU Admission in Critically Ill Patients: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials

Matsuoka, Ayaka Yoshihiro, Shodai Shida, Haruka Aikawa, Gen Fujinami, Yoshihisa Kawamura, Yusuke Nakanishi, Nobuto Shimizu, Motohiro Watanabe, Shinichi Sugimoto, Kensuke Taito, Shunsuke Inoue, Shigeaki 神戸大学

2023.09

概要

Previous systematic review and meta-analysis indicates that rehabilitation within a week of intensive care unit (ICU) admission benefits physical function in critically ill patients. This updated systematic review and meta-analysis aim to clarify effects of initiating rehabilitation within 72 h of ICU admission on long-term physical, cognitive, and mental health. We systematically searched the MEDLINE, Cochrane Central Register of Controlled Trials, and Igaku Chuo Zasshi for randomized controlled trials (RCTs) between April 2019 and November 2022 to add to the previous review. Two investigators independently selected and extracted data. Pooled effect estimates for muscle strength, cognitive function, mental health after discharge, and adverse events were calculated. Evidence certainty was assessed via Grading of Recommendations, Assessment, Development, and Evaluations. Eleven RCTs were included in the meta-analysis. Early rehabilitation may improve muscle strength (three trials; standard mean difference [SMD], 0.16; 95% confidence interval [CI], −0.04–0.36) and cognitive function (two trials; SMD, 0.54; 95% CI, −0.13–1.20). Contrastingly, early mobilization showed limited impact on mental health or adverse events. In summary, initiating rehabilitation for critically ill patients within 72 h may improve physical and cognitive function to prevent post-intensive care syndrome without increasing adverse events. The effect on mental function remains uncertain.

この論文で使われている画像

参考文献

1.

2.

3.

4.

5.

6.

7.

8.

9.

Kawakami, D.; Fujitani, S.; Morimoto, T.; Dote, H.; Takita, M.; Takaba, A.; Hino, M.; Nakamura, M.; Irie, H.; Adachi, T.; et al.

Prevalence of post-intensive care syndrome among Japanese intensive care unit patients: A prospective, multicenter, observational

J-PICS study. Crit. Care 2021, 25, 69. [CrossRef]

Needham, D.M.; Davidson, J.; Cohen, H.; Hopkins, R.O.; Weinert, C.; Wunsch, H.; Zawistowski, C.; Bemis-Dougherty, A.; Berney,

S.C.; Bienvenu, O.J.; et al. Improving long-term outcomes after discharge from intensive care unit: Report from a stakeholders’

conference. Crit. Care Med. 2012, 40, 502–509. [CrossRef]

Dinglas, V.D.; Aronson Friedman, L.; Colantuoni, E.; Mendez-Tellez, P.A.; Shanholtz, C.B.; Ciesla, N.D.; Pronovost, P.J.; Needham,

D.M. Muscle Weakness and 5-Year Survival in Acute Respiratory Distress Syndrome Survivors. Crit. Care Med. 2017, 45, 446–453.

[CrossRef] [PubMed]

Maley, J.H.; Brewster, I.; Mayoral, I.; Siruckova, R.; Adams, S.; McGraw, K.A.; Piech, A.A.; Detsky, M.; Mikkelsen, M.E. Resilience

in Survivors of Critical Illness in the Context of the Survivors’ Experience and Recovery. Ann. Am. Thorac. Soc. 2016, 13, 1351–1360.

[CrossRef] [PubMed]

Inoue, S.; Hatakeyama, J.; Kondo, Y.; Hifumi, T.; Sakuramoto, H.; Kawasaki, T.; Taito, S.; Nakamura, K.; Unoki, T.; Kawai, Y.; et al.

Post-intensive care syndrome: Its pathophysiology, prevention, and future directions. Acute Med. Surg. 2019, 6, 233–246.

[CrossRef] [PubMed]

Ziganshina, E.E.; Ziganshin, A.M. Anaerobic digestion of chicken manure in the presence of magnetite, granular activated carbon,

and biochar: Operation of anaerobic reactors and microbial community structure. Microorganisms 2022, 10, 1422. [CrossRef]

Fuke, R.; Hifumi, T.; Kondo, Y.; Hatakeyama, J.; Takei, T.; Yamakawa, K.; Inoue, S.; Nishida, O. Early rehabilitation to prevent

postintensive care syndrome in patients with critical illness: A systematic review and meta-analysis. BMJ Open 2018, 8, e019998.

[CrossRef] [PubMed]

Okada, Y.; Unoki, T.; Matsuishi, Y.; Egawa, Y.; Hayashida, K.; Inoue, S. Early versus delayed mobilization for in-hospital mortality

and health-related quality of life among critically ill patients: A systematic review and meta-analysis. J. Intensive Care 2019, 7, 57.

[CrossRef]

Fuest, K.; Schaller, S.J. Recent evidence on early mobilization in critical-Ill patients. Curr. Opin. Anaesthesiol. 2018, 31, 144–150.

[CrossRef]

J. Clin. Med. 2023, 12, 5888

10.

11.

12.

13.

14.

15.

16.

17.

18.

19.

20.

21.

22.

23.

24.

25.

26.

27.

28.

29.

30.

12 of 13

Egi, M.; Ogura, H.; Yatabe, T.; Atagi, K.; Inoue, S.; Iba, T.; Kakihana, Y.; Kawasaki, T.; Kushimoto, S.; Kuroda, Y.; et al. The

Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020). J. Intensive Care 2021, 9, 53.

[CrossRef]

Devlin, J.W.; Skrobik, Y.; Gélinas, C.; Needham, D.M.; Slooter, A.J.C.; Pandharipande, P.P.; Watson, P.L.; Weinhouse, G.L.;

Nunnally, M.E.; Rochwerg, B.; et al. Clinical practice guidelines for the prevention and management of pain, agitation/sedation,

delirium, immobility, and sleep disruption in adult patients in the ICU. Crit. Care Med. 2018, 46, e825–e873. [CrossRef] [PubMed]

Kuhn, K.F.; Schaller, S.J. Comment on Early versus delayed mobilization for in-hospital mortality and health-related quality of

life among critically ill patients: A systematic review and meta-analysis (Okada et al., Journal of Intensive Care 2019). J. Intensive

Care 2020, 8, 21. [CrossRef]

Sterne, J.A.C.; Savovi´c, J.; Page, M.J.; Elbers, R.G.; Blencowe, N.S.; Boutron, I.; Cates, C.J.; Cheng, H.Y.; Corbett, M.S.;

Eldridge, S.M.; et al. RoB 2: A revised tool for assessing risk of bias in randomised trials. BMJ 2019, 366, l4898. [CrossRef]

[PubMed]

Higgins, J.P.T.; Thomas, J.; Chandler, J.; Cumpston, M.; Li, T.; Page, M.J.; Welch, V.A. (Eds.) Cochrane Handbook for Systematic

Reviews of Interventions Version 6.4 (Updated August 2023). Cochrane, 2023. Available online: www.training.cochrane.org/

handbook (accessed on 4 September 2023).

Atkins, D.; Best, D.; Briss, P.A.; Eccles, M.; Falck-Ytter, Y.; Flottorp, S.; Guyatt, G.H.; Harbour, R.T.; Haugh, M.C.; Henry, D.; et al.

Grading quality of evidence and strength of recommendations. BMJ 2004, 328, 1490. [CrossRef] [PubMed]

Brummel, N.E.; Girard, T.D.; Ely, E.W.; Pandharipande, P.P.; Morandi, A.; Hughes, C.G.; Graves, A.J.; Shintani, A.; Murphy, E.;

Work, B.; et al. Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical

patients: The Activity and Cognitive Therapy in ICU (ACT-ICU) trial. Intensive Care Med. 2014, 40, 370–379. [CrossRef]

Hodgson, C.L.; Bailey, M.; Bellomo, R.; Berney, S.; Buhr, H.; Denehy, L.; Gabbe, B.; Harrold, M.; Higgins, A.; Iwashyna, T.J.; et al.

A Bbinational multicenter pilot feasibility randomized controlled trial of early goal-directed mobilization in the ICU. Crit. Care

Med. 2016, 44, 1145–1152. [CrossRef]

Kayambu, G.; Boots, R.; Paratz, J. Early physical rehabilitation in intensive care patients with sepsis syndromes: A pilot

randomised controlled trial. Intensive Care Med. 2015, 41, 865–874. [CrossRef]

Moradian, S.T.; Najafloo, M.; Mahmoudi, H.; Ghiasi, M.S. Early mobilization reduces the atelectasis and pleural effusion in

patients undergoing coronary artery bypass graft surgery: A randomized clinical trial. J. Vasc. Nurs. 2017, 35, 141–145. [CrossRef]

Morris, P.E.; Berry, M.J.; Files, D.C.; Thompson, J.C.; Hauser, J.; Flores, L.; Dhar, S.; Chmelo, E.; Lovato, J.; Case, L.D.; et al.

Standardized rehabilitation and hospital length of stay among patients with acute respiratory failure: A randomized clinical trial.

JAMA 2016, 315, 2694–2702. [CrossRef]

Schaller, S.J.; Anstey, M.; Blobner, M.; Edrich, T.; Grabitz, S.D.; Gradwohl-Matis, I.; Heim, M.; Houle, T.; Kurth, T.;

Latronico, N.; et al. Early, goal-directed mobilisation in the surgical intensive care unit: A randomised controlled trial. Lancet

2016, 388, 1377–1388. [CrossRef]

Schweickert, W.D.; Pohlman, M.C.; Pohlman, A.S.; Nigos, C.; Pawlik, A.J.; Esbrook, C.L.; Spears, L.; Miller, M.; Franczyk, M.;

Deprizio, D.; et al. Early physical and occupational therapy in mechanically ventilated, critically ill patients: A randomised

controlled trial. Lancet 2009, 373, 1874–1882. [CrossRef]

ECMO-PT Study Investigators; International ECMO Network. Early mobilisation during extracorporeal membrane oxygenation

was safe and feasible: A pilot randomised controlled trial. Intensive Care Med. 2020, 46, 1057–1059. [CrossRef]

Patel, B.K.; Wolfe, K.S.; Patel, S.B.; Dugan, K.C.; Esbrook, C.L.; Pawlik, A.J.; Stulberg, M.; Kemple, C.; Teele, M.; Zeleny, E.; et al.

Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: A randomised controlled trial. Lancet

Respir. Med. 2023, 11, 563–572. [CrossRef]

Schujmann, D.S.; Teixeira Gomes, T.; Lunardi, A.C.; Zoccoler Lamano, M.; Fragoso, A.; Pimentel, M.; Peso, C.N.; Araujo, P.;

Fu, C. Impact of a progressive mobility program on the functional status, respiratory, and muscular systems of ICU patients: A

randomized and controlled trial. Crit. Care Med. 2020, 48, 491–497. [CrossRef] [PubMed]

Zhou, W.; Yu, L.; Fan, Y.; Shi, B.; Wang, X.; Chen, T.; Yu, H.; Liu, J.; Wang, X.; Liu, C.; et al. Effect of early mobilization combined

with early nutrition on acquired weakness in critically ill patients (EMAS): A dual-center, randomized controlled trial. PLoS ONE

2022, 17, e0268599. [CrossRef]

Nydahl, P.; Sricharoenchai, T.; Chandra, S.; Kundt, F.S.; Huang, M.; Fischill, M.; Needham, D.M. Safety of patient mobilization

and rehabilitation in the Intensive Care Unit. Systematic review with meta-analysis. Ann. Am. Thorac. Soc. 2017, 14, 766–777.

[CrossRef] [PubMed]

The TEAM Study Investigators and the ANZICS Clinical Trials Group; Hodgson, C.L.; Bailey, M.; Bellomo, R.; Brickell, K.;

Broadley, T.; Buhr, H.; Gabbe, B.J.; Gould, D.W.; Harrold, M.; et al. Early Active Mobilization during Mechanical Ventilation in the

ICU. N. Engl. J. Med. 2022, 387, 1747–1758. [CrossRef] [PubMed]

Goodwin, V.A.; Allan, L.; Bethel, A.; Cowley, A.; Cross, J.L.; Day, J.; Drummond, A.; Hall, A.J.; Howard, M.; Morley, N.; et al.

Rehabilitation to enable recovery from COVID-19: A rapid systematic review. Physiotherapy 2021, 111, 4–22. [CrossRef] [PubMed]

Menges, D.; Seiler, B.; Tomonaga, Y.; Schwenkglenks, M.; Puhan, M.A.; Yebyo, H.G. Systematic early versus late mobilization or

standard early mobilization in mechanically ventilated adult ICU patients: Systematic review and meta-analysis. Crit. Care 2021,

25, 16. [CrossRef] [PubMed]

J. Clin. Med. 2023, 12, 5888

31.

32.

33.

34.

35.

36.

13 of 13

Tipping, C.J.; Harrold, M.; Holland, A.; Romero, L.; Nisbet, T.; Hodgson, C.L. The effects of active mobilisation and rehabilitation

in ICU on mortality and function: A systematic review. Intensive Care Med. 2017, 43, 171–183. [CrossRef]

Doiron, K.A.; Hoffmann, T.C.; Beller, E.M. Early intervention (mobilization or active exercise) for critically ill adults in the

intensive care unit. Cochrane Database Syst. Rev. 2018, 3, CD010754. [CrossRef] [PubMed]

Tipping, C.J.; Young, P.J.; Romero, L.; Saxena, M.K.; Dulhunty, J.; Hodgson, C.L. A systematic review of measurements of physical

function in critically ill adults. Crit. Care Resusc. 2012, 14, 302–311. Available online: https://www.ncbi.nlm.nih.gov/pubmed/23

230880 (accessed on 4 September 2023). [PubMed]

Wang, J.; Ren, D.; Liu, Y.; Wang, Y.; Zhang, B.; Xiao, Q. Effects of early mobilization on the prognosis of critically ill patients: A

systematic review and meta-analysis. Int. J. Nurs. Stud. 2020, 110, 103708. [CrossRef] [PubMed]

Deana, C.; Vetrugno, L.; Cortegiani, A.; Mongodi, S.; Salve, G.; Mangiagalli, M.; Boscolo, A.; Pettenuzzo, T.; Miori, S.; Sanna, A.;

et al. Quality of Life in COVID-Related ARDS Patients One Year after Intensive Care Discharge (Odissea Study): A Multicenter

Observational Study. J. Clin. Med. 2023, 12, 1058. [CrossRef] [PubMed]

Wang, Y.T.; Lang, J.K.; Haines, K.J.; Skinner, E.H.; Haines, T.P. Physical rehabilitation in the ICU: A systematic review and

meta-analysis. Crit. Care Med. 2022, 50, 375–388. [CrossRef]

Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual

author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to

people or property resulting from any ideas, methods, instructions or products referred to in the content.

...

参考文献をもっと見る

全国の大学の
卒論・修論・学位論文

一発検索!

この論文の関連論文を見る