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Longitudinal association between mental health and future antibiotic prescriptions in healthy adults: Results from the LOHAS

Tochitani, Kentaro 京都大学 DOI:10.14989/doctor.k24093

2022.05.23

概要

Antimicrobial resistance (AMR) has become a global problem in recent years. Currently, the number of deaths attributed to AMR is approximately 70,000 per year worldwide, and it is predicted to increase to 10 million by 2050 unless measures are taken [1]. To prevent AMR, it is necessary to use antibiotics appropriately and reduce their use. The World Health Organization launched a global action plan to combat antimicrobial-resistant bacteria in 2015, and it asked member countries to approve national action plans within 2 years [2]. In 2016, the government of Japan launched a national action plan, and the goal was to reduce antimicrobial use by 33% by the year 2020 [3].

Reducing antibiotic prescriptions involves understanding associated factors, mainly medical staff factors and patient factors. Medical staff factors include age or sex of the physicians, practice volume, and regional characteristics [4, 5]. Similarly, patient factors may include age, sex, smoking status, socioeconomic status, and comorbidities [6–8]. Regarding factors associated with mental health, psychological stress might be associated with an increased occurrence of infectious diseases [9, 10], but there have been no studies of whether people with lower quality of life (QOL) are likely to be prescribed antibiotics.

This study aimed to analyze the longitudinal associations of mental health and subjective physical functioning of healthy community-dwelling Japanese adults with their future antibiotic prescriptions to clarify the individual characteristics associated with the increase in antibiotic prescriptions.

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参考文献

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