Intrasellar Chordoma Mimicking Pituitary Macroadenoma with Hyperprolactinemia and Hypopituitarism: Clinical Images with a Surgical Video

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Figure legends

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Figure. 1 Preoperative computed tomography images. Sagittal brain window image (A)

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shows an isodense sellar lesion. Sagittal (B) and axial (C) bone window images show

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ballooning of the sella turcica and thinning of the dorsum sellae without intratumoral

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calcification or clival invasion.

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Figure. 2 Preoperative sagittal (A–C), coronal (E, F), and axial (G, H) magnetic resonance

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images with position of coronal and axial slice (H). A solid sellar tumor with the right

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cavernous sinus invasion shows iso-intensity on T1-weighted image (A), very high-intensity

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on T2-weighted images (C, E, G), and well-enhanced margin with heterogeneous internal

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enhancement on contrast-enhanced T1-weighted images (B, D, F).

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Figure. 3 Postoperative sagittal (A), coronal (B), and axial (C) contrast-enhanced T1-

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weighted images confirm total resection of the tumor with anatomic preservation of the

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normal pituitary gland tissue (white arrow in B).

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Figure. 4 Photomicrographs show tissue corresponding to histopathological diagnosis of

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chordoma (A, B).

Fig. 1

Axial

CT

Sagittal

Fig. 2

CE-T1WI

T2WI

Sagittal

Coronal

Axial

Axial

CE-T1WI

Coronal

Sagittal

T1WI

Fig. 3

Coronal

Axial

Postoperative CE-T1WI

Sagittal

Fig. 4

Brachyury

Histopathology

H-E

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