1) Yabuki S, Fukumori N, Takegami M, et al.
Prevalence of lumbar spinal stenosis, using the
diagnostic support tool, and correlated factors in
Japan: a population-based study. J Orthop Sci.
2013;18:893-900. DOI: 10.1007/s00776-0130455-5.
2)Yoshida M, Shima K, Taniguchi Y, Tamaki T,
Tanaka T. Hypertrophied ligamentum flavum in
lumbar spinal canal stenosis. Pathogenesis and
morphologic and immunohistochemical observation. Spine (Phila Pa 1976). 1992;17:1353-60.
DOI: 10.1097/00007632-199211000-00015.
3) Viejo-Fuertes D, Liguoro D, Rivel J, Midy D,
Guerin J. Morphologic and histologic study of the
ligamentum flavum in the thoraco-lumbar region.
Surg Radiol Anat. 1998;20:171-6. DOI: 10.1007/
BF01628891.
4)Okuda T, Baba I, Fujimoto Y, et al. The pathology of ligamentum flavum in degenerative lumbar
disease. Spine (Phila Pa 1976). 2004;29:1689-97.
DOI: 10.1097/01.brs.0000132510.25378.8c.
5) Kosaka H, Sairyo K, Biyani A, et al. Pathomechanism of loss of elasticity and hypertrophy
of lumbar ligamentum flavum in elderly patients
with lumbar spinal canal stenosis. Spine (Phila Pa 1976). 2007;32:2805-11. DOI: 10.1097/
BRS.0b013e31815b650f.
6) Zhong ZM, Zha DS, Xiao WD, et al. Hypertrophy of ligamentum flavum in lumbar spine
stenosis associated with the increased expression
of connective tissue growth factor. J Orthop Res.
2011;29:1592-7. DOI: 10.1002/jor.21431.
7)Yabe Y, Hagiwara Y, Ando A, et al. Chondrogenic and fibrotic process in the ligamentum flavum of patients with lumbar spinal canal stenosis.
Spine (Phila Pa 1976). 2015;40:429-35. DOI:
10.1097/BRS.0000000000000795.
8) Yabe Y, Hagiwara Y, Tsuchiya M, et al. Decreased elastic fibers and increased proteoglycans
in the ligamentum flavum of patients with lumbar
spinal canal stenosis. J Orthop Res. 2016;34:12417. DOI: 10.1002/jor.23130.
9) Sugimoto K, Nakamura T, Tokunaga T, et al.
KONO et al.
Matrix metalloproteinase promotes elastic fiber
degradation in ligamentum flavum degeneration.
PLoS One. 2018;13:e0200872. DOI: 10.1371/
journal.pone.0200872.
10) Osakabe T, Hayashi M, Hasegawa K, et al.
Age- and gender-related changes in ligament
components. Ann Clin Biochem. 2001;38:527-32.
DOI: 10.1177/000456320103800510.
11)Wang Z, Li XD, Li MQ, Wang QP. Changes
in basic metabolic elements associated with the
degeneration and ossification of ligamenta flava. J Spinal Cord Med. 2008;31:279-84. DOI:
10.1080/10790268.2008.11760723.
12)Mikawa Y, Hamagami H, Shikata J, Yamamuro
T. Elastin in the human intervertebral disk. A histological and biochemical study comparing it with
elastin in the human yellow ligament. Arch Orthop Trauma Surg (1978). 1986;105:343-9. DOI:
10.1007/BF00449940.
13) Osago H, Kobayashi-Miura M, Hamasaki Y,
Hara N, Hiyoshi M, Tsuchiya M. Complete solubilization of cartilage using the heat-stable protease thermolysin for comprehensive GAG analysis.
Anal Biochem. 2018;548:115-8. DOI: 10.1016/
j.ab.2018.02.028.
14)Farndale RW, Buttle DJ, Barrett AJ. Improved
quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene
blue. Biochim Biophys Acta. 1986;883:173-7.
DOI: 10.1016/0304-4165(86)90306-5.
1 5) Woessner JF Jr. The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid.
Arch Biochem Biophys. 1 9 6 1;9 3:4 4 0-7. DOI:
10.1016/0003-9861(61)90291-0.
16)Reddy GK, Enwemeka CS. A simplified method for the analysis of hydroxyproline in biological tissues. Clin Biochem. 1996;29:225-9. DOI:
10.1016/0009-9120(96)00003-6.
17) Albarbarawi O, Barton A, Lin Z, et al. Measurement of urinary total desmosine and isodesmosine using isotope-dilution liquid chromatography-tandem mass spectrometry. Anal Chem.
2010;82:3745-50. DOI: 10.1021/ac100152f.
18) Yamauchi M, Taga Y, Hattori S, Shiiba M,
Terajima M. Analysis of collagen and elastin
cross-links. Methods Cell Biol. 2018;143:115-32.
DOI: 10.1016/bs.mcb.2017.08.006.
19)Miller GR, Smith CA, Stauber WT. Determination of fibrosis from cryostat sections using high
performance liquid chromatography: skeletal muscle. Histochem J. 1999;31:89-94. DOI: 10.1023/
a:1003592710740.
20) Rasmussen BL, Bruenger E, Sandberg LB.
A new method for purification of mature elastin. Anal Biochem. 1 9 7 5;6 4:2 5 5-9. DOI:
10.1016/0003-2697(75)90426-1.
21) Paz MA, Keith DA, Gallop PM. Elastin isolation and cross-linking. Methods Enzymol.
1982;82:571-587. DOI: 10.1016/0076-6879(82)
82088-0.
22)Nakagawa H, Mikawa Y, Watanabe R. Elastin
in the human posterior longitudinal ligament and
spinal dura. A histologic and biochemical study.
Spine (Phila Pa 1976). 1994;19:2164-9. DOI:
10.1097/00007632-199410000-00006.
23)Fukuyama S, Nakamura T, Ikeda T, et al. The Effect of Mechnical Stress on the Lumber Yellow Ligament. Orthopedics & Traumatology. 1994;43:13151318. doi: 10.5035/nishiseisai.43.1315.(Eng Abstr)
24)Sato N, Taniguchi T, Goda Y, et al. Proteomic
Analysis of Human Tendon and Ligament: Solubilization and Analysis of Insoluble Extracellular Matrix in Connective Tissues. J Proteome
Res. 2 0 1 6:1 5:4 7 0 9-4 7 2 1. DOI: 1 0.1 0 2 1/acs.
jproteome.6b00806.
2 5) Soskel NT. High-performance liquid chromatographic quantitation of desmosine plus
isodesmosine in elastin and whole tissue hydrolysates. Anal Biochem. 1987;160:98-104. DOI:
10.1016/0003-2697(87)90618-x.
26) Hayashi M, Osakabe T, Ushio F, Seyama Y.
Qualitative change in the elastin from the calcified portion of human artery. Japanese Journal
of Geriatrics. 1999;36:404-7. DOI: 10.3143/
geriatrics.36.404.(Eng Abstr)
...