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大学・研究所にある論文を検索できる 「Association between Inter-atrial Septum Motion and Persistent Atrial Fibrillation Recurrence after Catheter Ablation」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

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Association between Inter-atrial Septum Motion and Persistent Atrial Fibrillation Recurrence after Catheter Ablation

Kobayashi, Hideki Okada, Ayako Tabata, Hiroaki Shoin, Wataru Okano, Takahiro Yoshie, Koji Oguchi, Yasutaka Kato, Ken Motoki, Hirohiko Shoda, Morio Kuwahara, Koichiro 信州大学

2021.08.19

概要

Background : Recently, several echocardiographic parameters have been proposed as predictors of the recurrence of persistent atrial fibrillation (psAF) after catheter ablation (CA). This study aimed to evaluate whether a decrease in inter-atrial septum (IAS) motion was associated with recurrence of psAF after CA.

Methods : A total of 103 consecutive patients who underwent CA for psAF were retrospectively reviewed. IAS motion was measured 48-72 hours before CA using transesophageal echocardiography. The primary outcome was AF recurrence beyond 3 months post-ablation. The follow-up period was 12 months after CA.

Results : PsAF recurrence after CA occurred in 29 (28.2 %) patients. The median value of IAS motion was 4.1 mm (interquartile range 2.4, 5.4), and the decline in IAS motion was an independent predictor of AF recurrence in a multivariate analysis of various models. Kaplan-Meier analysis showed that AF recurrence was significantly higher in the low IAS motion group (IAS motion<4.2, n=47) than in the high IAS motion group (IAS motion ≥ 4.2, n=52) (log-rank test, p=0.001). A negative correlation was observed between IAS motion and left atrial volume (LAV), and conversely, a positive correlation was found between IAS motion and left atrial appendage flow velocity. The low IAS motion group had a higher left atrial pressure (LAP) than the high IAS motion group.

Conclusions : PsAF recurrence after CA was associated with reduced IAS motion. Decreased IAS motion could be an important finding suggestive of left atrial remodeling as well as LAV enlargement and increasing LAP. Shinshu Med J 69 : 189―201, 2021

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参考文献

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