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Current status of umbilical cord blood storage and provision to private biobanks by institutions handling childbirth in Japan

Murata, Maho Kawabe, Kenichiro Hatta, Taichi Maeda, Shoichi Fujita, Misao 京都大学 DOI:10.1186/s12910-022-00830-8

2022

概要

[Background] The Act Regarding the Promotion of the Appropriate Supply of Hematopoietic Stem Cells for Transplant regulates only how public banks store and provide umbilical cord blood (UCB) for research or transplantation. Japan had no laws to regulate how the private banks manage the procedures, harvesting, preparation, and storage of such blood. As a result, the status of UCB distribution remains unknown. We conducted a survey to investigate the current status of UCB storage and provision to private biobanks by Japanese institutions that handle childbirth. [Methods] Questionnaire forms were mailed to 3, 277 facilities handling childbirth that were registered in the Japan Council for Quality Health Care website. [Results] Of the 1, 192 institutions handling childbirth that participated in the survey (response rate: 36.7%), 34.4% responded that they currently provide UCB to private biobanks, while 16.1% of facilities did so in the past. Moreover, some institutions currently provide or formerly provided UCB to medical treatment facilities (2.6%), research institutions (5.9%), companies (2.2%), or overseas treatment facilities, research institutions, or companies (0.3%). A certain number of institutions handling childbirth did not even provide explanations or obtain consent when the UCB was harvested from private bank users. [Conclusions] This is the first study to determine the status of UCB provision to private banks by Japanese institutions handling childbirth. Future studies will need to examine in detail how institutions handling childbirth provide explanations to private bank users and UCB providers as well as how these institutions obtain consent.

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参考文献

1. Gluckman E, Broxmeyer HA, Auerbach AD, Friedman HS, Douglas GW,

Devergie A, et al. Hematopoietic reconstitution in a patient with Fanconi’s

anemia by means of umbilical-cord blood from an HLA-identical sibling.

N Engl J Med. 1989;321(17):1174–8.

2. Munoz J, Shah N, Rezvani K, Hosing C, Bollard CM, Oran B, et al. Concise

review: umbilical cord blood transplantation: past, present, and future.

Stem Cells Transl Med. 2014;3(12):1435–43.

3. ClinicalTrials gov [Internet]. U.S. National Library of Medicine [cited 2022

Jul 28]. https://ClinicalTrials.gov/.

4. Roura S, Pujal JM, Gálvez-Montón C, Bayes-Genis A. The role and potential

of umbilical cord blood in an era of new therapies: a review. Stem Cell

Res Ther. 2015;6(1):123.

5. Damien P, Allan DS. Regenerative therapy and immune modulation

using umbilical cord blood-derived cells. Biol Blood Marrow Transpl.

2015;21(9):1545–54.

6. Kurtzberg J. A history of cord blood banking and transplantation. Stem

Cells Transl Med. 2017;6(5):1309–11.

A Self-archived copy in

Kyoto University Research Information Repository

https://repository.kulib.kyoto-u.ac.jp

Murata et al. BMC Medical Ethics

(2022) 23:92

7. Japanese Red Cross Society [Internet]. Hematopoietic stem cell transplant information service. State of Openness of Storage of Umbilical Cord

Blood in Japan. 2021 Sep 1 [cited 2021 Sep 30]. (in Japanese). https://

www.bs.jrc.or.jp/bmdc/cordblooddonor/m3_04_statistics.html.

8. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al.

Induction of pluripotent stem cells from adult human fibroblasts by

defined factors. Cell. 2007;131(5):861–72.

9. Ministry of Health, Labour and Welfare. Minutes of the 33rd meeting of

the Hematopoietic Stem Cell Transplant Panel, Disease Control Subcommittee, Health Science Council of the Ministry of Health, Labour, and

Welfare. 2012 Jul 18 [cited 2021 Sep 30]. (in Japanese). http://www.mhlw.

go.jp/stf/shingi/2r9852000002pyuc.html.

10. Ministry of Health, Labour and Welfare. Regarding the creation of the

Guidelines on the Operation of the Ministerial Ordinances Concerning

the Standards for Maintaining the Quality of Umbilical Cord Blood used in

Transplants. 2013 Dec 27 [cited 2021 Sep 30]. (in Japanese). https://www.

mhlw.go.jp/web/t_doc?dataId=00tb9768&dataType=1&pageNo=1.

11. Fujita M, Hatta T, Ozeki R, Akabayashi A. The current status of clinics providing private practice cell therapy in Japan. Regen Med.

2016;11(1):23–32.

12. Lau D, Ogbogu U, Taylor B, Stafinski T, Menon D, Caulfield T. Stem cell clinics online: the direct-to-consumer portrayal of stem cell medicine. Cell

Stem Cell. 2008;3(6):591–4.

13. The Japan Council for Quality Health Care. News Letter. 2016 Nov 1[cited

2021 Sep 30]. (in Japanese). https://jcqhc.or.jp/wp-content/themes/

jcqhc/pdf/download/news_letter_201611.pdf.

14. Hokkaido cord blood bank [Internet]. Japan Red Cross Society. [cited

2021 Jan 18]. (in Japanese). https://www.bs.jrc.or.jp/hkd/bbc/special/m6_

02_02_02_00001160.html.

15. Japan Red Cross Society. Kanto Koh Shin Etsu cord blood bank [Internet].

[cited 2021 Jan 18]. (in Japanese). https://www.bs.jrc.or.jp/ktks/bbc/speci

al/m6_03_03_onegai.html.

16. General Incorporated. Association. Chubu cord blood bank [Internet].

[cited 2021 Jan 18]. (in Japanese). https://www.chubu-cbb.org/entry5.

html#p1.

17. Japan Red Cross Society. Kinki cord blood bank [Internet]. [cited 2021 Jan

18]. (in Japanese). https://www.bs.jrc.or.jp/kk/bbc/special/m6_02_05_

saitai_teikyonoonega.html.

18. Specified Nonprofit Organization. Hyogo cord blood bank [Internet].

[cited 2021 Jan 18]. (in Japanese). https://www.saitaiketu.org/about/

hospital.

19. Japan Red Cross Society. Kyushu cord blood bank. [cited 2021 Jan 18]. (in

Japanese). https://www.bs.jrc.or.jp/bc9/bbc/special/m6_02_00_index.

html.

20. Ministry of Health, Labour and Welfare. Report of the survey on the current state of private umbilical cord blood banks. 2017 Sep 12 [cited 2021

Sep 30]. (in Japanese). https://www.mhlw.go.jp/seisakunitsuite/bunya/

kenkou_iryou/kenkou/ishoku/dl/saitaiketsu02-2.pdf.

21. The Japan Society for Hematopoietic Cell Transplantation [Internet].

Statement on private umbilical cord blood banks. 2002 Aug 19 [cited

2021 Sep 30]. (in Japanese). https://www.jshct.com/uploads/files/news/

seimei20020819.pdf.

22. Japan Association of Obstetricians and Gynecologists News [Internet].

Note of caution regarding private storage of umbilical cord blood. [cited

2021 Sep 30]. (in Japanese). https://www.jaog.or.jp/sep2012/News/

11May2005.htm.

23. Six arrested in relation to umbilical cord blood. Yomiuri Shimbun. 2017

Aug 27; Tokyo Morning Edition, p35 (in Japanese).

24. Umbilical cord blood intermediary found guilty (Osaka). Asahi Shimbun.

2017 Dec 21: Morning Edition, p31 (in Japanese).

25. Behind the scenes/Legal loopholes spur illicit cord blood use. The Jpn

News. 2017 Oct 26 (in Japanese).

26. Four cord blood banks closed their business. Yomiuri Shimbun. 2017 Nov

23 (in Japanese).

27. Petrini C. Ethical issues in umbilical cord blood banking: a comparative

analysis of documents from national and international institutions. Transfusion. 2013;53(4):902–10.

28. Ballen KK, Spitzer TR, Yeap BY, McAfee S, Dey BR, Attar E, et al. Double

unrelated reduced-intensity umbilical cord blood transplantation in

adults. Biol Blood Marrow Transpl. 2007;13(1):82–9.

Page 7 of 7

29. Ministry of Health, Labour and Welfare. Hospital report 2017. [cited 2021

Sep 30]. (in Japanese). https://www.mhlw.go.jp/toukei/saikin/hw/iryosd/

17/dl/09gaikyo29.pdf.

30. Ministry of Health, Labour and Welfare. Summary of vital statistics. [cited

2022 Jul 28]. (in Japanese). https://www.mhlw.go.jp/toukei/saikin/hw/

jinkou/kakutei16/dl/03_h1.pdf.

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Current status of umbilical cord blood storage and provision to private biobanks by institutions handling childbirth in Japan

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Current status of umbilical cord blood storage and provision to private biobanks by institutions handling childbirth in Japan

概要

この論文で使われている画像

関連論文

Financial risks posed by unproven cell interventions: Estimation of refunds from medical expense deductions in Japan

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