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大学・研究所にある論文を検索できる 「Impact of body mass index on in-hospital mortality for six acute cardiovascular diseases in Japan」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。
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Impact of body mass index on in-hospital mortality for six acute cardiovascular diseases in Japan

Yoshida, Naofumi Ogawa, Masato Nakai, Michikazu Kanaoka, Koshiro Sumita, Yoko Emoto, Takuo Saito, Yoshihiro Yamamoto, Hiroyuki Izawa, Kazuhiro P. Sakai, Yoshitada Hirota, Yushi Ogawa, Wataru Iwanaga, Yoshitaka Miyamoto, Yoshihiro Yamashita, Tomoya Hirata, Ken-ichi 神戸大学

2022.11.07

概要

Body mass index (BMI) distribution and its impact on cardiovascular disease (CVD) vary between Asian and western populations. The study aimed to reveal time-related trends in the prevalence of obesity and underweight and safe ranges of BMI in Japanese patients with CVD. We analyzed 5,020,464 records from the national Japanese Registry of All Cardiac and Vascular Diseases—Diagnosis Procedure Combination dataset over time (2012–2019) and evaluated BMI trends and the impact on in-hospital mortality for six acute CVDs: acute heart failure (AHF), acute myocardial infarction (AMI), acute aortic dissection (AAD), ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH). Patients were categorized into five groups using the WHO Asian-BMI criteria: underweight (< 18.5 kg/m2), normal (18.5–22.9 kg/m2), overweight at risk (23.0–24.9 kg/m2), obese I (25.0–29.9 kg/m2), and obese II (≥ 30.0 kg/m2). Age was significantly and inversely related to high BMI for all diseases (P < 0.001). The proportion of BMI categories significantly altered over time; annual BMI trends showed a significant and gradual increase, except AAD. In adjusted mixed models, underweight was significantly associated with a high risk of in-hospital mortality in all CVD patients (AHF, OR 1.41, 95% CI 1.35–1.48, P < 0.001; AMI, OR 1.27, 95% CI 1.20–1.35, P < 0.001; AAD, OR 1.23, 95% CI 1.16–1.32, P < 0.001; IS, OR 1.45, 95% CI 1.41–1.50, P < 0.001; ICH, OR 1.18, 95% CI 1.13–1.22, P < 0.001; SAH, OR 1.17, 95% CI 1.10–1.26, P < 0.001). Moreover, obese I and II groups were significantly associated with a higher incidence of in-hospital mortality, except AHF and IS. Age was associated with in-hospital mortality for all BMI categories in six CVD patients. BMI increased annually in patients with six types of CVDs. Although underweight BMI was associated with high mortality rates, the impact of obesity on in-hospital mortality differs among CVD types.

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参考文献

1. Van Gaal, L. F., Mertens, I. L. & De Block, C. E. Mechanisms linking obesity with cardiovascular disease. Nature 444, 875–880. https://doi.org/10.1038/nature05487 (2006).

2. Kivimäki, M. et al. Overweight, obesity, and risk of cardiometabolic multimorbidity: Pooled analysis of individual-level data for 120 813 adults from 16 cohort studies from the USA and Europe. Lancet Public Health 2, e277–e285. https://doi.org/10.1016/ S2468-2667(17)30074-9 (2017).

3. GBD. Obesity collaborators. Health effects of overweight and obesity in 195 countries over 25 years. N. Engl. J. Med. 2017 2015; 377:13–27.

4. Poirier, P. et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: An update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 113, 898–918. https://doi.org/10.1161/CIRCULATIONAHA.106.171016 (2006).

5. Zheng, W. et al. Association between body-mass index and risk of death in more than 1 million Asians. N. Engl. J. Med. 364, 719–729. https://doi.org/10.1056/NEJMoa1010679 (2011).

6. Blüher, M. Obesity: Global epidemiology and pathogenesis. Nat. Rev. Endocrinol. 15, 288–298. https://doi.org/10.1038/s41574- 019-0176-8 (2019).

7. Lavie, C. J. et al. Healthy weight and obesity prevention: JACC Health Promotion Series. J. Am. Coll. Cardiol. 72, 1506–1531. https:// doi.org/10.1016/j.jacc.2018.08.1037 (2018).

8. Lavie, C. J., Milani, R. V. & Ventura, H. O. Obesity and cardiovascular disease: Risk factor, paradox, and impact of weight loss. J. Am. Coll. Cardiol. 53, 1925–1932. https://doi.org/10.1016/j.jacc.2008.12.068 (2009).

9. Yatsuya, H. et al. Global trend in overweight and obesity and its association with cardiovascular disease incidence. Circ. J. 78, 2807–2818. https://doi.org/10.1253/circj.cj-14-0850 (2014).

10. Chen, Y. et al. Association between body mass index and cardiovascular disease mortality in east Asians and South Asians: Pooled analysis of prospective data from the Asia Cohort Consortium. BMJ 347, f5446. https://doi.org/10.1136/bmj.f5446 (2013).

11. Anker, S. D. & Coats, A. J. Cardiac cachexia: A syndrome with impaired survival and immune and neuroendocrine activation. Chest 115, 836–847. https://doi.org/10.1378/chest.115.3.836 (1999).

12. Balachandran, A., de Beer, J., James, K. S., van Wissen, L. & Janssen, F. Comparison of population aging in Europe and Asia using a time-consistent and comparative aging measure. J. Aging Health 32, 340–351. https://doi.org/10.1177/0898264318824180 (2020).

13. Yasuda, S., Miyamoto, Y. & Ogawa, H. Current status of cardiovascular medicine in the aging society of Japan. Circulation 138, 965–967. https://doi.org/10.1161/CIRCULATIONAHA.118.035858 (2018).

14. Nakao, K. et al. Prescription rates of guideline-directed medications are associated with in-hospital mortality among Japanese patients with acute myocardial infarction: A report From JROAD—DPC Study. J. Am. Heart Assoc. 8, e009692. https://doi.org/10. 1161/JAHA.118.009692 (2019).

15. Yamashita, Y. et al. Temporal trends in the practice pattern for venous thromboembolism in Japan: Insight From JROAD-DPC. J. Am. Heart. Assoc. 9, e014582. https://doi.org/10.1161/JAHA.119.014582 (2020).

16. Kanaoka, K. et al. Role of climatic factors in the incidence of takotsubo syndrome: A nationwide study from 2012 to 2016. ESC Heart Fail. 7, 2629–2636. https://doi.org/10.1002/ehf2.12843 (2020).

17. Matoba, T. et al. Institutional characteristics and prognosis of acute myocardial infarction with cardiogenic shock in Japan—Analy- sis from the JROAD/JROAD-DPC Database. Circ. J. 85, 1797–1805. https://doi.org/10.1253/circj.CJ-20-0655 (2021).

18. Itoh, H. et al. Reverse J-shaped relationship between body mass index and in-hospital mortality of patients hospitalized for heart failure in Japan. Heart Vessels 36, 383–392. https://doi.org/10.1007/s00380-020-01699-6 (2021).

19. Ross, J. S. et al. Hospital volume and 30-day mortality for three common medical conditions. N. Engl. J. Med. 362, 1110–1118. https://doi.org/10.1056/NEJMsa0907130 (2010).

20. World Health Organization. Regional Office for the Western P. The Asia-Pacific Perspective: Redefining Obesity and Its Treatment (Health Communications, 2000).

21. Bhaskaran, K., dos-Santos-Silva, I., Leon, D.A., Douglas, I.J., & Smeeth, L. Association of BMI with overall and cause-specific mortality: A population-based cohort study of 3.6 million adults in the UK. Lancet Diabetes Endocrinol. 2018; 6:944–953. https:// doi.org/10.1016/S2213-8587(18)30288-2.

22. Calle, E. E., Thun, M. J., Petrelli, J. M., Rodriguez, C. & Heath, C. W. Body-mass index and mortality in a prospective cohort of U.S. adults. N. Engl. J. Med. 341, 1097–1105. https://doi.org/10.1056/NEJM199910073411501 (1999).

23. Deng, F. et al. BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: Findings from the Care for cardiovascular Disease project in China. BMC Cardiovasc. Disord. 20, 270. https://doi.org/10.1186/s12872-020-01544-8 (2020).

24. Miyazawa, I. et al. Twelve-year trends of increasing overweight and obesity in patients with diabetes: The Shiga Diabetes Clinical Survey. Endocr. J. 65, 527–536. https://doi.org/10.1507/endocrj.EJ17-0415 (2018).

25. Ferrucci, L., Fabbri, E. & Fabbri, E. Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Nat. Rev. Cardiol. 15, 505–522. https://doi.org/10.1038/s41569-018-0064-2 (2018).

26. Clegg, A., Young, J., Iliffe, S., Rikkert, M. O. & Rockwood, K. Frailty in elderly people. Lancet 381, 752–762. https://doi.org/10. 1016/S0140-6736(12)62167-9 (2013).

27. Fukuma, S., Iizuka, T., Ikenoue, T. & Tsugawa, Y. Association of the national health guidance intervention for obesity and car- diovascular risks with health outcomes among Japanese men. JAMA Intern. Med. 180, 1630–1637. https://doi.org/10.1001/jamai nternmed.2020.4334 (2020).

28. Fried, L. P. et al. Frailty in older adults: Evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56, M146–M156. https://doi. org/10.1093/gerona/56.3.m146 (2001).

29. Pandey, A., Kitzman, D. & Reeves, G. Frailty is intertwined with heart failure: Mechanisms, prevalence, prognosis, assessment, and management’. JACC Heart Fail. 7, 1001–1011. https://doi.org/10.1016/j.jchf.2019.10.005 (2019).

30. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. Lancet. 2017; 390:2627–2642. https://doi.org/10.1016/S0140-6736(17)32129-3.

31. Wilson, P. W. F., D’Agostino, R. B., Sullivan, L., Parise, H. & Kannel, W. B. Overweight and obesity as determinants of cardiovascular risk: The Framingham experience. Arch. Intern. Med. 162, 1867–1872. https://doi.org/10.1001/archinte.162.16.1867 (2002).

32. Gadde, K. M., Martin, C. K., Berthoud, H. R. & Heymsfield, S. B. Obesity: Pathophysiology and management. J. Am. Coll. Cardiol. 71, 69–84. https://doi.org/10.1016/j.jacc.2017.11.011 (2018).

33. Vest, A. R., Wu, Y., Hachamovitch, R., Young, J. B. & Cho, L. The heart failure overweight/obesity survival paradox: The missing sex link. JACC Heart Fail. 3, 917–926. https://doi.org/10.1016/j.jchf.2015.06.009 (2015).

34. Carbone, S. et al. Obesity paradox in cardiovascular disease: Where do we stand?. Vasc. Health Risk Manag. 15, 89–100. https:// doi.org/10.2147/VHRM.S168946 (2019).

35. Ortega, F. B. et al. The intriguing metabolically healthy but obese phenotype: Cardiovascular prognosis and role of fitness. Eur. Heart J. 34, 389–397. https://doi.org/10.1093/eurheartj/ehs174 (2013).

36. Smith, G. I., Mittendorfer, B. & Klein, S. Metabolically healthy obesity: Facts and fantasies. J. Clin. Invest. 129, 3978–3989. https:// doi.org/10.1172/JCI129186 (2019).

37. Itoh, H. et al. Metabolically healthy obesity and the risk of cardiovascular disease in the general population—Analysis of a nation- wide epidemiological database. Circ. J. 85, 914–920. https://doi.org/10.1253/circj.CJ-20-1040 (2021).

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