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大学・研究所にある論文を検索できる 「The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

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The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex

Kondo, Tatsuya Nakamura, Yui Nojima, Shingo Yao, Min Imai, Tomoya 京都大学 DOI:10.1002/1873-3468.14495

2022.12

概要

Cellulose synthase has two distinct functions: synthesis of the cellulose molecule (polymerization) and assembling the synthesized cellulose chains into the crystalline microfibril (crystallization). In the type I bacterial cellulose synthase (Bcs) complex, four major subunits --BcsA, BcsB, BcsC and BcsD-- work in a coordinated manner. This study showed that the crystallization subunit BcsD interacts with the polymerization complex BcsAB in two modes: direct protein–protein interactions and indirect interactions through the product cellulose. We hypothesized that the former and latter modes represent the basal and active states of type I bacterial cellulose synthase, respectively, and this dynamic behaviour of the BcsD protein regulates the crystallization process of cellulose chains.

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参考文献

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