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Poor physical performance is associated with osteosarcopenic obesity in the elderly Chinese community.

MA YIXUAN 東北大学

2021.03.25

概要

Objective: Osteosarcopenic obesity (FOS) is a recently defined triad of osteoporosis/ osteopenia, sarcopenia, and obesity. The aims of this study were to investigate the association between FOS and physical performance in Chinese elderly communities.

Methods: Our study population comprised residents of the township central hospital in the suburban of Tianjin, China. Participants (n=303; percent body fat (PBF): ≥ 25% for men and ≥ 32% for women) were assessed using the direct segmental multi frequency bioelectrical impedance analysis (BIA) for body composition. Sarcopenia was defined as the lower 20th percentile of appendicular skeletal muscle mass/height2 (ASMI). A quantitative ultrasound scan of each participants' calcaneus with a T score ≤−1.0 was used to identify the prevalence of osteopenia/osteoporosis. We divided people into four groups: obesity only (F), osteopenia obesity (FO), sarcopenic obesity (FS), and osteosarcopenic obesity (FOS). We assessed the physical performance by grip strength, 4-m walk speed test (WS) and timed up and go test (TUGT).

Results: A total of 303 participants had completed data, (89 men, 214 women; mean age of 68.8±6.0 years). The prevalence of FOS was 10.2% (men: 15.70%, women: 7.9%). After multiple adjustment, WS was significantly slower in FOS group when compared with the F group in men (mean value 95%CI was 0.84(0.69,0.99)) and women (mean value 95%CI was 0.93(0.84, 1.02)). TUGT significantly poorer in men (mean value 95%CI was 13.3(10.6, 15.9)) and women (mean value 95% CI was 12.4(11.2, 13.7)) with FOS when compared with the F group. Furthermore, the FOS group in women also had a significantly poorer TUGT compared with the FO group. The result of grip strength is significantly lower in women FS and FOS groups when compared with the F group (mean value 95%CI was 16.4(14.5, 18.2) and 16.1(13.9, 18.3). But the results of grip strength in men showed no significant differences in any of the group.

Conclusion: In Chinese community-dwelling elderly, slower WS and lower balance function were associated with FOS in men and women. Lower grip strength was associated with FS and FOS in women.

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