Analysis of Stereochemical Stability of Dynamic Chiral Molecules using an Automated Microflow Measurement System

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(9) The values of half-live of optical activity were calculated by

Eyring equation on the assumption that transmission coefficient is

one.

(10) Uncertainty of activation parameters owing to the narrow

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(13) Asano, S.; Takahashi, Y.; Maki, T.; Muranaka, Y.; Cherkasov,

N.; Mae, K., Contactless Mass Transfer for Intra-droplet Extraction.

Sci. Rep. 2020, 10, 7685. The developed software in this work can

be downloaded with detailed operation procedure at

https://github.com/ShusakuASANO/KYOCHAN_Chiral.

(14) Regueira, T.; Yan, W.; Stenby, E. H., Densities of the Binary

Systems n-Hexane plus n-Decane and n-Hexane plus n-Hexadecane

up to 60 MPa and 463 K. J. Chem. Eng. Data 2015, 60, 3631-3645.

(15) The enantiomeric excess values of the samples were determined by UV signal of PDA detector to avoid the influence of artifacts of CD detector.

(16) The range of Hrac‡ and Srac‡ are 26.9-27.8 kcal·mol–1 and

5.04-7.72 cal·mol–1·K–1, respectively, in consideration of the SE of

Eyring plot.

(17) 2a was newly synthesized in this study. See, the Supporting

Information for the detail of the synthesis.

(18) Garcia-Miaja, G.; Troncoso, J.; Romani, L., Density and Heat

Capacity as a Function of Temperature for Binary Mixtures of 1Butyl-3-methylpyridinium Tetrafluoroborate plus Water, plus Ethanol, and plus Nitromethane. J. Chem. Eng. Data 2007, 52, 22612265.

(19) The range of Hrac‡ and Srac‡ are 25.4-26.1 kcal·mol–1 and

2.49-4.39 cal·mol–1·K–1, respectively, in consideration of the SE of

Eyring plot.

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