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Associations between parental bonding during childhood and functional recovery in patients with schizophrenia

石井, 洵平 東京慈恵会医科大学 DOI:info:doi/10.1371/journal.pone.0240504

2021.10.22

概要

Introduction
Schizophrenia is believed to be etiologically associated with environmental factors. Poor parental bonding, especially arising from “low care” and “overprotection,” may contribute to the prognosis in patients with psychosis. In the present study, we investigated the associa- tions between the aforementioned two different parental bonding types and the prognosis, in terms of the functional recovery, of patients with schizophrenia.

Methods
A total of 89 patients with schizophrenia were recruited, and 79 patients were registered for the study. After the parental bonding types and representative childhood adverse events were assessed, specific items on the PANSS were assessed at 0 and 24 weeks of the study period to define the functional prognosis.

Results
At the end of the 24-week follow-up period, 36% of the patients were judged as showing recovery from schizophrenia. The score for “overprotective attitude,” but not that for “low care,” was found to be significantly higher in the non-recovery (defined below) group. Explor- atory logistic regression analysis identified only “overprotective attitude” of the parents as being predictive of non-recovery. Moreover, a significant negative correlation was found between “low care” and “overprotective attitude” only in the non-recovery group.

Conclusion
In the present study, we showed that an overprotective attitude of the parents was associ- ated with non-recovery in patients with schizophrenia.

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