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Measurement of serum procalcitonin concentrations in calves with bovine respiratory disease

Koshiishi, Tomoko Shibutani, Shusaku Chuma, Takehisa Iwata, Hiroyuki 北海道大学

2023.11.27

概要

Bovine respiratory disease (BRD) is an important and complex disease caused by various pathogens and
stressors. Although BRD is often caused by viruses, secondary bacterial infections can worsen symptoms
and prognosis. Due to this viral-bacterial synergy, the evaluation of bacterial infections in BRD is
important for the diagnosis and prognosis of BRD. In this study, we analyzed the serum concentrations
of procalcitonin (PCT), a biomarker of bacterial infection, in 41 calves with BRD. We demonstrate
that when calves are categorized into PCT-positive and PCT-negative groups based on serum PCT
concentrations, the PCT-positive group shows more persistently high BRD scores. These findings
suggest that the measurement of serum PCT is potentially useful for the diagnosis and prognosis of
calves with BRD. ...

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