Abbott, A. Biology’s new dimension. Nature, 424, 870–872, 2003
Aizawa, T. et al. Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus. Cancer Sci, 102, 122–129, 2011
Albro, M. B. et al. Accumulation of exogenous activated TGF-β in the superficial zoneof articular cartilage. Biophys J, 104, 1794–1804, 2013
Arima, Y. et al. Targeting of cancer stem cells by differentiation therapy. Cancer Sci, 111, 2689–2695, 2020
Arranz, L. et al. Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms. Nature, 512, 78–81, 2014
Ayuso, J. M. et al. Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events. Neuro Oncol, 19, 503–513, 2017
Baker, G. J. et al. Mechanisms of Glioma Formation: Iterative Perivascular Glioma Growth and Invasion Leads to Tumor Progression, VEGF-Independent Vascularization, and Resistance to Antiangiogenic Therapy. Neoplasia (United States), 16, 543–561, 2014
Baker, G. J. et al. Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy. Neoplasia, 16, 543–61,2014
Bao, S. et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature, 444, 756–760, 2006
Barczyk, M. et al. Integrins. Cell Tissue Res, 339, 269–280, 2010
Barnes, J. M. et al. A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma. Nat Cell Biol, 20, 1203–1214, 2018
Bastola, S. et al. Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy. Nat Commun, 11, 4660, 2020
Beadle, C. et al. The role of myosin II in glioma invasion of the brain. Mol Biol Cell, 19, 3357–68, 2008
Bi, J. et al. Altered cellular metabolism in gliomas — an emerging landscape of actionable co-dependency targets. Nat Rev Cancer, 20, 57–70, 2020
Bonnet, D. et al. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med, 3, 730–7, 1997
Brennan, C. W. et al. The somatic genomic landscape of glioblastoma. Cell, 155, 462, 2013
Cain, R. J. et al. Phosphoinositide 3-kinases in cell migration. Biol Cell, 101, 13–29, 2009
Calabrese, C. et al. A perivascular niche for brain tumor stem cells. Cancer Cell, 11, 69–82, 2007
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature, 455, 1061–8, 2008
Chen, J. et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature, 488, 522–526, 2012
Cheng, L. et al. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell, 153, 139–152, 2013
Cheng, L. et al. Elevated invasive potential of glioblastoma stem cells. Biochem Biophys Res Commun, 406, 643–648, 2011
Ciasca, G. et al. Nano-mechanical signature of brain tumours. Nanoscale, 8, 19629– 19643, 2016
Clarke, M. F. et al. Cancer stem cells - Perspectives on current status and future directions: AACR workshop on cancer stem cells. in Cancer Research vol. 66 9339–9344, (2006).
Crampton, S. J. et al. Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation? J Neurochem, 120, 964–73, 2012
Cuddapah, V. A. et al. A neurocentric perspective on glioma invasion. Nat Rev Neurosci, 15, 455–465, 2014
David, C. J. et al. Contextual determinants of TGFβ action in development, immunity and cancer. Nat Rev Mol Cell Biol, 19, 419–435, 2018
Denais, C. M. et al. Nuclear envelope rupture and repair during cancer cell migration. Science (80- ), 352, 353–358, 2016
Ebben, J. D. et al. The cancer stem cell paradigm: A new understanding of tumor development and treatment. Expert Opinion on Therapeutic Targets vol. 14 621–632, 2010
Ehtesham, M. et al. CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Lett, 274, 305–12, 2009
Falcicchia, C. et al. Involvement of p38 mapk in synaptic function and dysfunction. Int J Mol Sci, 21, 1–14, 2020
Farin, A. et al. Transplanted glioma cells migrate and proliferate on host brain vasculature: a dynamic analysis. Glia, 53, 799–808, 2006
Fearon, E. R. et al. A genetic model for colorectal tumorigenesis. Cell, 61, 759–67, 1990
Filatova, A. et al. The cancer stem cell niche(s): The crosstalk between glioma stem cells and their microenvironment. Biochim Biophys Acta - Gen Subj, 1830, 2496– 2508, 2013
Friedl, P. et al. New dimensions in cell migration. Nat Rev Mol Cell Biol, 13, 743–747,2012
G. Gritsenko, P. et al. Interstitial guidance of cancer invasion. J Pathol, 226, 185–199, 2012
Geer, C. P. et al. Interstitial fluid flow along white matter tracts: a potentially important mechanism for the dissemination of primary brain tumors. J Neurooncol, 32, 193–201, 1997
Giese, A. et al. Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment. J Clin Oncol, 21, 1624–1636, 2003
Gimple, R. C. et al. Glioblastoma stem cells: Lessons from the tumor hierarchy in a lethal cancer. Genes Dev, 33, 591–609, 2019
de Gooijer, M. C. et al. An Experimenter’s Guide to Glioblastoma Invasion Pathways. Trends in Molecular Medicine vol. 24 763–780, 2018
Gritsenko, P. G. et al. Adaptive adhesion systems mediate glioma cell invasion in complex environments. J Cell Sci, 131, 2018
Guha, A. et al. Proliferation of human malignant astrocytomas is dependent on Ras activation. Oncogene, 15, 2755–65, 1997
Hannon, G. J. et al. Pl5INK4B is a potentia| effector of TGF-β-induced cell cycle arrest. Nature, 371, 257–261, 1994
Hompland, T. et al. Interstitial fluid pressure and associated lymph node metastasis revealed in tumors by dynamic contrast-enhanced MRI. Cancer Res, 72, 4899– 4908, 2012
Huang, C. et al. MAP kinases and cell migration. J Cell Sci, 117, 4619–4628, 2004
Huang, D. W. et al. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc, 4, 44–57, 2009
Huang, Y. C. et al. Stromal cell-derived factor-1 enhances motility and integrin up-regulation through CXCR4, ERK and NF-κB-dependent pathway in human lung cancer cells. Biochem Pharmacol, 74, 1702–1712, 2007
Huijbers, I. J. et al. A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion. PLoS One, 5, 1–12, 2010
Hutmacher, D. W. et al. Can tissue engineering concepts advance tumor biology research? Trends Biotechnol, 28, 125–133, 2010
Iliff, J. J. et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. Sci Transl Med, 4, 147ra111, 2012
Infanger, D. W. et al. Glioblastoma stem cells are regulated by interleukin-8 signaling in a tumoral perivascular niche. Cancer Res, 73, 7079–7089, 2013
Inoue, A. et al. Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity. Int J Oncol, 37, 1121–31, 2010
Iosif, R. E. et al. Tumor necrosis factor receptor 1 is a negative regulator of progenitor proliferation in adult hippocampal neurogenesis. J Neurosci, 26, 9703–9712, 2006
Kingsmore, K. M. et al. MRI analysis to map interstitial flow in the brain tumor microenvironment. APL Bioeng, 2, 031905, 2018
Kingsmore, K. M. et al. Interstitial flow differentially increases patient-derived glioblastoma stem cell invasion via CXCR4, CXCL12, and CD44-mediated mechanisms. Integr Biol (Camb), 8, 1246–1260, 2016
Lathia, J. et al. Cancer stem cells in glioblastoma. Genes Dev, 29, 1203–1217, 2015
Lathia, J. D. et al. Laminin alpha 2 enables glioblastoma stem cell growth. Ann Neurol, 72, 766–778, 2012
Lavoie, H. et al. ERK signalling: a master regulator of cell behaviour, life and fate. Nat Rev Mol Cell Biol, 21, 607–632, 2020
Li, T.-T. T. et al. Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen. Blood, 103, 3396–3402, 2004
Louis, D. N. et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol, 131, 803–820, 2016
McCoy, M. G. et al. Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties. Sci Rep, 9, 1–14, 2019
Miroshnikova, Y. A. et al. Tissue mechanics promote IDH1-dependent HIF1α-tenascin C feedback to regulate glioblastoma aggression. Nat Cell Biol, 18, 1336–1345, 2016
Munson, J. M. et al. Interstitial flow in a 3D microenvironment increases glioma invasion by a CXCR4-dependent mechanism. Cancer Res, 73, 1536–46, 2013
Namba, N. et al. Heterogeneous Glioma Cell Invasion under Interstitial Flow Depending on Their Differentiation Status. Tissue Eng - Part A, 27, 467–478, 2021
Neftel, C. et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell, 178, 835-849.e21, 2019
Nowell, P. C. The clonal evolution of tumor cell populations. Science, 194, 23–8, 1976 Ostrom, Q. T. et al. CBTRUS statistical report: Primary brain and other central nervous system tumors diagnosed in the United States in 2011-2015. Neuro Oncol, 20,iv1–iv86, 2018
Osuka, S. et al. Overcoming therapeutic resistance in glioblastoma: the way forward. J Clin Invest, 127, 415–426, 2017
Patel, A. P. et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science, 344, 1396–401, 2014
Piccirillo, S. G. M. et al. Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells. Nature, 444, 761–765, 2006
Pistollato, F. et al. Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma. Stem Cells, 28, 851–862, 2010
Polacheck, W. J. et al. Mechanotransduction of fluid stresses governs 3D cell migration.
Proc Natl Acad Sci U S A, 111, 2447–2452, 2014
Principe, D. R. et al. TGF-β: Duality of function between tumor prevention and carcinogenesis. Journal of the National Cancer Institute vol. 106 2014
Qiang, L. et al. HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway. Cell Death Differ, 19, 284–294, 2012
Qiu, B. et al. Human brain glioma stem cells are more invasive than their differentiated progeny cells in vitro. J Clin Neurosci, 19, 130–134, 2012
Quail, D. F. et al. The Microenvironmental Landscape of Brain Tumors. Cancer Cell, 31, 326–341, 2017
Rao, S. et al. CXCL12 mediates trophic interactions between endothelial and tumor cells in glioblastoma. PLoS One, 7, e33005, 2012
Sadatsuki, R. et al. Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression. J Orthop Res, 1– 10, 2016 doi:10.1002/jor.23318
Sampetrean, O. et al. Invasion precedes tumor mass formation in a malignant brain tumor model of genetically modified neural stem cells. Neoplasia, 13, 784–91, 2011
Sampetrean, O. et al. Characteristics of glioma stem cells. Brain Tumor Pathol, 30, 209–14, 2013
Sampetrean, O. et al. Modeling phenotypes of malignant gliomas. Cancer Sci, 109, 6– 14, 2018
Sánchez-Martín, F. J. et al. Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells. PLoS One, 8, 1–13, 2013
Sano, H. et al. Control of vessel diameters mediated by flow-induced outward vascular remodeling in vitro. Biofabrication, 12, 2020
Scherer, H. J. Structural development in gliomas. Am J Cancer, 34, 333–351, 1938
Serrano, M. et al. Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85, 27–37, 1996
Shannon, P. et al. Pathological and Molecular Progression of Astrocytomas in a GFAP:12V-Ha-Ras Mouse Astrocytoma Model. Am J Pathol, 167, 859–867, 2005
Shao, N. et al. Interleukin-8 upregulates integrin β3 expression and promotes estrogen receptor-negative breast cancer cell invasion by activating the PI3K/Akt/NF-κB pathway. Cancer Lett, 8, 1–8, 2015
Shibao, S. et al. Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model. Neuro Oncol, 20, 343–354, 2018
Shin, Y. et al. Microfluidic assay for simultaneous culture of multiple cell types on surfaces or within hydrogels. Nat Protoc, 7, 1247–59, 2012
Singh, S. K. et al. Identification of human brain tumour initiating cells. Nature, 432, 396–401, 2004
Snuderl, M. et al. Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma. Cancer Cell, 20, 810–817, 2011
Sottoriva, A. et al. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc Natl Acad Sci U S A, 110, 4009–4014, 2013
Strojnik, T. et al. Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival. Surg Neurol, 68, 133–143, 2007
Stupp, R. et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III
study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol, 10, 459–466, 2009
Stupp, R. et al. Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma. N Engl J Med, 352, 987–996, 2005
Sudo, R. et al. Transport-mediated angiogenesis in 3D epithelial coculture. FASEB J, 23, 2155–2164, 2009
Sun, X. et al. Mathematical modeling reveals a critical role for cyclin D1 dynamics in phenotype switching during glioma differentiation. FEBS Lett, 589, 2304–2311, 2015
Szerlip, N. J. et al. Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci U S A, 109, 3041–3046, 2012
Takanaga, H. et al. cAMP-induced Astrocytic Differentiation of C6 Glioma Cells Is Mediated by Autocrine Interleukin-6. J Biol Chem, 279, 15441–15447, 2004
Tamura, R. et al. Visualization of spatiotemporal dynamics of human glioma stem cell invasion. Mol Brain, 12, 45, 2019
De Thé, H. Differentiation therapy revisited. Nat Rev Cancer, 18, 117–127, 2018
Toole, B. P. Hyaluronan-CD44 interactions in cancer: Paradoxes and possibilities. Clinical Cancer Research vol. 15 7462–7468, 2009
Truong, D. et al. A three-dimensional (3D) organotypic microfluidic model for glioma stem cells – Vascular interactions. Biomaterials, 198, 63–77, 2019
Ulmasov, B. et al. Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice. C Cell Mol Gastroenterol Hepatol, 2, 499–518, 2016
Ulmasov, B. et al. Differences in the degree of cerulein-induced chronic pancreatitis in C57BL/6 mouse substrains lead to new insights in identification of potential risk factors in the development of chronic pancreatitis. Am J Pathol, 183, 692–708, 2013
Verhaak, R. G. W. et al. Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell, 17, 98–110, 2010
Wachs, F. P. et al. Transforming growth factor-β1 is a negative modulator of adult neurogenesis. J Neuropathol Exp Neurol, 65, 358–370, 2006
Watkins, S. et al. Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells. Nat Commun, 5, 4196, 2014
Wen, P. Y. et al. Malignant gliomas in adults. N Engl J Med, 359, 492–507, 2008
Wolf, K. et al. Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force. J Cell Biol, 201, 1069– 1084, 2013
Wolf, K. J. et al. A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles. Proc Natl Acad Sci U S A, 117, 2020
Wolf, K. J. et al. A 3D topographical model of parenchymal infiltration and perivascular invasion in glioblastoma. APL Bioeng, 2, 031903, 2018
Xie, Q. et al. Targeting adaptive glioblastoma: An overview of proliferation and invasion. Neuro Oncol, 16, 1575–1584, 2014
Xing, F. et al. The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes. Cell Rep, 18, 468–481, 2017
Yadav, V. et al. CXCR4 increases in-vivo glioma perivascular invasion, and reduces radiation induced apoptosis: A genetic knockdown study. Oncotarget, 7, 83701– 83719, 2016
Ye, X. et al. Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF-β1 Signaling Pathway. J Immunol, 189, 444–453, 2012
Young, M. E. et al. Estimation of diffusion coefficients of proteins. Biotechnol Bioeng, 22, 947–955, 1980
Zanca, C. et al. Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. Genes Dev, 31, 1212–1227, 2017
Zhou, Y. et al. Autocrine BMP4 Signaling Enhances Tumor Aggressiveness via Promoting Wnt/β-Catenin Signaling in IDH1-mutant Gliomas. Transl Oncol, 13, 125–134, 2020
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