[1] I.B. McInnes, G. Schett, Cytokines in the pathogenesis of rheumatoid arthritis, Nat. Rev. Immunol. 7 (2007) 429–442.
[2] D.L. Scott, F. Wolfe, T.W.J. Huizinga, Rheumatoid arthritis, Lancet 376 (2010) 1094–1108.
[3] G. Schett, E. Gravallese, Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment, Nat. Rev. Rheumatol. 8 (2012) 656–664.
[4] K.P. Machold, T.A. Stamm, V.P.K. Nell, S. Pflugbeil, D. Aletaha, G. Steiner, M. Uffmann, et al., Very recent onset rheumatoid arthritis: clinical and serological patient characteristics associated with radiographic progression over the first years of disease, Rheumatology 46 (2007) 342–349.
[5] S. Bobo Tanner, C.F. Moore Jr., A review of the use of dual-energy X-ray absorptiometry (DXA) in rheumatology, Open Access Rheumatol. 4 (2012) 99–107.
[6] U.M. Døhn, B. Ejbjerg, A. Boonen, M.L. Hetland, M.S. Hansen, L.S. Knudsen, et al., No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study, Ann. Rheum. Dis. 70 (2011) 252–258.
[7] R. Kocijan, S. Finzel, M. Englbrecht, K. Engelke, J. Rech, G. Schett, Differences in bone structure between rheumatoid arthritis and psoriatic arthritis patients relative to autoantibody positivity, Ann. Rheum. Dis. 73 (2014) 2022–2028.
[8] N.N. Haroon, E. Szabo, J.M. Raboud, H. Mcdonald-Blumer, L. Fung, R.G. Josse, et al., Alterations of bone mineral density, bone microarchitecture and strength in patients with ankylosing spondylitis: a cross-sectional study using high-resolution peripheral quantitative computerized tomography and finite element analysis, Arthritis Res. Ther. 17 (2015) 1–9.
[9] F. Stemmler, D. Simon, A.M. Liphardt, M. Englbrecht, J. Rech, A.J. Hueber, et al., Biomechanical properties of bone are impaired in patients with ACPA-positive rheumatoid arthritis and associated with the occurrence of fractures, Ann. Rheum. Dis. 77 (2018) 973–980.
[10] A.A. Drosos, E. Pelechas, P.V. Voulgari, Treatment strategies are more important than drugs in the management of rheumatoid arthritis, Clin. Rheumatol. 39 (2020) 1363–1368.
[11] T. Nakano, K. Kaibara, Y. Tabata, N. Nagata, S. Enomoto, E. Marukawa, et al., Unique alignment and texture of biological apatite crystallites in typical calcified tissues analyzed by microbeam x-ray diffractometer system, Bone 31 (2002) 479–487.
[12] T. Ishimoto, T. Nakano, Y. Umakoshi, M. Yamamoto, Y. Tabata, Degree of biological apatite c-axis orientation rather than bone mineral density controls mechanical function in bone regenerated using recombinant bone morphogenetic protein-2, J. Bone Miner. Res. 28 (2013) 1170–1179.
[13] R. Ozasa, T. Ishimoto, S. Miyabe, J. Hashimoto, M. Hirao, H. Yoshikawa, et al., Osteoporosis changes collagen/apatite orientation and Young’s modulus in vertebral cortical bone of rat, Calcif. Tissue Int. 104 (2019) 449–460.
[14] T. Moriishi, R. Ozasa, T. Ishimoto, T. Nakano, T. Hasegawa, T. Miyazaki, et al., Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass, PLoS Genet. 16 (2020), e1008586.
[15] M.P.E. Wenger, L. Bozec, M.A. Horton, P. Mesquidaz, Mechanical properties of collagen fibrils, Biophys. J. 93 (2007) 1255–1263.
[16] B. Viswanath, R. Raghavan, U. Ramamurty, N. Ravishankar, Mechanical properties and anisotropy in hydroxyapatite single crystals, Scr. Mater. 57 (2007) 361–364.
[17] B.L. Riggs, L.J. Melton Iii, Bone turnover matters: the raloxifene treatment paradox of dramatic decreases in vertebral fractures without commensurate increases in bone density, J. Bone Miner. Res. 17 (2002) 11–14.
[18] P. Ammann, Bone strength and its determinants, Osteoporos. Int. 58 (2003) 403–407.
[19] T. Wakamatsu, Y. Iwasaki, S. Yamamoto, K. Matsuo, S. Goto, I. Narita, et al., Type-I angiotensin II receptor blockade reduces uremia-induced deterioration of bone material properties, J. Bone Miner. Res. 36 (2021) 67–79.
[20] A. Sekita, A. Matsugaki, T. Nakano, Disruption of collagen/apatite alignment impairs bone mechanical function in osteoblastic metastasis induced by prostate cancer, Bone 97 (2017) 83–93.
[21] T. Ishimoto, K. Kawahara, A. Matsugaki, H. Kamioka, T. Nakano, Quantitative evaluation of osteocyte morphology and bone anisotropic extracellular matrix in rat femur, Calcif. Tissue Int. 109 (2021) 434–444.
[22] M. Tanaka, A. Matsugaki, T. Ishimoto, T. Nakano, Evaluation of crystallographic orientation of biological apatite at vertebral cortical bone in ovariectomized cynomolgus monkey treated with minodronic acid and alendronate, J. Bone Miner. Metab. 34 (2016) 234–241.
[23] A. Sekita, A. Matsugaki, T. Ishimoto, T. Nakano, Synchronous disruption of anisotropic arrangement of the osteocyte network and collagen/apatite in melanoma bone metastasis, J. Struct. Biol. 197 (2017) 260–270.
[24] A. Matsugaki, S. Matsumoto, T. Nakano, A novel role of interleukin-6 as a regulatory factor of inflammation-associated deterioration in osteoblast arrangement, Int. J. Mol. Sci. 21 (2020) 6659.
[25] A. Larsen, K. Dale, M. Eek, Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference films, Acta Radiol. Diagn. 18 (1977) 481–491.
[26] L. Sharma, J.S. Chmiel, O. Almagor, D. Felson, A. Guermazi, F. Roemer, et al., The role of varus and valgus alignment in the initial development of knee cartilage damage by MRI: the MOST study, Ann. Rheum. Dis. 72 (2013) 235–240.
[27] B.J. Fregly, Y. Bei, M.E. Sylvester, Experimental evaluation of an elastic foundation model to predict contact pressures in knee replacements, J. Biomech. 36 (2003) 1659–1668.
[28] L.L. Frazer, E.M. Santschi, K.J. Fischer, Impact of a void in the equine medial femoral condyle on bone stresses and peak contact pressures in a finite element model, Vet. Surg. 48 (2019) 237–246.
[29] C.N. Anderson, A.F. Anderson, Tibial eminence fractures, Clin. Sports Med. 30 (2011) 727–742.
[30] Z.G. Jia, W. Li, Z.R. Zhou, Mechanical characterization of stomach tissue under uniaxial tensile action, J. Biomech. 48 (2015) 651–658.
[31] T. Ishimoto, K. Yamada, H. Takahashi, M. Takahata, M. Ito, T. Hanawa, et al., Trabecular health of vertebrae based on anisotropy in trabecular architecture and collagen/apatite micro-arrangement after implantation of intervertebral fusion cages in the sheep spine, Bone 108 (2018) 25–33.
[32] T. Ishimoto, B. Sato, J.W. Lee, T. Nakano, Co-deteriorations of anisotropic extracellular matrix arrangement and intrinsic mechanical property in c-src deficient osteopetrotic mouse femur, Bone 103 (2017) 216–223.
[33] Y. Noyama, T. Nakano, T. Ishimoto, T. Sakai, H. Yoshikawa, Design and optimization of the oriented groove on the hip implant surface to promote bone microstructure integrity, Bone 52 (2013) 659–667.
[34] R. Ozasa, A. Matsugaki, Y. Isobe, T. Saku, H.S. Yun, T. Nakano, Construction of human induced pluripotent stem cell-derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model, J. Biomed. Mater. Res. A 106 (2018) 360–369.
[35] N.M. Kalyani, C.A. Ong, A.C. Lysaght, S.J. Haward, G.H. McKinley, K.M. Stankovic, Quantitative polarized light microscopy of unstained mammalian cochlear sections, J. Biomed. Opt. 18 (2013) 26021.
[36] W.J. Landis, K.J. Hodgens, M.J. Song, J. Arena, S. Kiyonaga, M. Marko, et al., Mineralization of collagen may occur on fibril surfaces: evidence from conventional and high-voltage electron microscopy and three-dimensional imaging, J. Struct. Biol. 117 (1996) 24–35.
[37] J.R. Matyas, L. Atley, M. Ionescu, D.R. Eyre, A.R. Poole, Analysis of cartilage biomarkers in the early phases of canine experimental osteoarthritis, Arthritis Rheumatol. 50 (2004) 543–552.
[38] Y. Wang, A.E. Wluka, J.P. Pelletier, J. Martel-Pelletier, F. Abram, C. Ding, et al., Meniscal extrusion predicts increases in subchondral bone marrow lesions and bone cysts and expansion of subchondral bone in osteoarthritic knees, Rheumatology 49 (2010) 997–1004.
[39] G. Li, J. Yin, J. Gao, N.J. Pavlos, C. Zhang, M.H. Zheng, Subchondral bone in osteoarthritis: insight into risk factors and microstructural changes, Arthritis Res. Ther. 15 (2013) 1–2.
[40] C.P. Figueiredo, D. Simon, M. Englbrecht, J. Haschka, A. Kleyer, S. Bayat, et al., Quantification and impact of secondary osteoarthritis in patients with anti–citrullinated protein antibody–positive rheumatoid arthritis, Arthritis Rheumatol. 68 (2016) 2114–2121.
[41] L. Solomon, Patterns of osteoarthritis of the hip, J. Bone Jt Surg. 58 (1976) 176–183.
[42] J.W. Lee, A. Kobayashi, T. Nakano, Crystallographic orientation of the c-axis of biological apatite as a new index of the quality of subchondral bone in knee joint osteoarthritis, J. Bone Miner. Metab. 35 (2017) 308–314.
[43] J. Wang, T. Ishimoto, T. Nakano, Unloading-induced degradation of the anisotropic arrangement of collagen/apatite in rat femurs, Calcif. Tissue Int. 100 (2017) 87–94.
[44] M. Kashii, J. Hashimoto, T. Nakano, Y. Umakoshi, H. Yoshikawa, Alendronate treatment promotes bone formation with a less anisotropic microstructure during intramembranous ossification in rats, J. Bone Miner. Metab. 26 (2008) 24–33.
[45] Y. Iwasaki, J.J. Kazama, H. Yamato, A. Matsugaki, T. Nakano, M. Fukagawa, Altered material properties are responsible for bone fragility in rats with chronic kidney injury, Bone 81 (2015) 247–254.
[46] T.A. Franz-Odendaal, B.K. Hall, P.E. Witten, Buried alive: how osteoblasts become osteocytes, Dev. Dyn. 235 (2006) 176–190.
[47] M. Zhou, S. Li, J.L. Pathak, Pro-inflammatory cytokines and osteocytes, Curr. Osteoporos. 17 (2019) 97–104.
[48] N. Nishimoto, T. Kishimoto, Humanized antihuman IL-6 receptor antibody, tocilizumab, Handb. Exp. Pharmacol. (2008) 151–160.
[49] S. Kang, T. Tanaka, H. Inoue, C. Ono, S. Hashimoto, Y. Kioi, et al., IL-6 trans- signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome, Proc. Natl. Acad. Sci. U. S. A. 117 (2020) 22351–22356.
[50] J.T. Sharp, M.D. Lidsky, L.C. Collins, J. Moreland, Methods of scoring the progression of radiologic changes in rheumatoid arthritis. Correlation of radiologic, clinical and laboratory abnormalities, Arthritis Rheum. 14 (1971) 706–720.
[51] D. Van Der Heijde, P. Van Riel, F. Gribnau, I. Nuver-Zwart, L. Van De Putte, Effects of hydroxychloroquine and sulphasalazine on progression of joint damage in rheumatoid arthritis, Lancet 333 (1989) 1036–1038.
[52] H.K. Genant, Y. Jiang, C. Peterfy, Y. Lu, J. R´edei, P.J. Countryman, Assessment of rheumatoid arthritis using a modified scoring method on digitized and original radiographs, Arthritis Rheum. 41 (1998) 1583–1590.
[53] T. Ishimoto, R. Suetoshi, D. Cretin, K. Hagihara, J. Hashimoto, A. Kobayashi, et al., Quantitative ultrasound (QUS) axial transmission method reflects anisotropy in micro-arrangement of apatite crystallites in human long bones: a study with 3- MHz-frequency ultrasound, Bone 127 (2019) 82–90.
[54] L. Knott, A.J. Bailey, Collagen cross-links in mineralizing tissues: a review of their chemistry, function, and clinical relevance, Bone 22 (1998) 181–187.
[55] M. Saito, K. Marumo, Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus, Osteoporos. Int. 21 (2010) 195–214.
[56] L.J.S. da Fonseca, V. Nunes-Souza, M.O.F. Goulart, L.A. Rabelo, Oxidative stress in rheumatoid arthritis: what the future might hold regarding novel biomarkers and add-on therapies, Oxidative Med. Cell. Longev. 14 (2019) 7536805.
[57] Y. Shinno, T. Ishimoto, M. Saito, R. Uemura, M. Arino, K. Marumo, Comprehensive analyses of how tubule occulusion and advanced glycation end-products diminish strength of aged dentin, Sci. Rep. 6 (2016) 19849.
[58] T. Matsuzaka, A. Matsugaki, T. Nakano, Control of osteoblast arrangement by osteocyte mechanoresponse through prostaglandin E2 signaling under oscillatory fluid flow stimuli, Biomaterials 27 (2021), 121203.
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