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Fabrication of paper-based microfluidic devices using a laser beam scanning technique

Hiep Dang Huy 広島大学

2020.09.18

概要

1.1 . Brief history of paper analytical devices
The paper-based microfluidic analytical device (P-PAD) has been
attracted great interest since it possesses beneficial characteristics such as easyto-use, biocompatible, inexpensive, and so on.1-3 Therefore, it is considered that
the P-PADs are especially important to use in developing countries where the
expensive equipments are rare to use because of the finance issues.
In 2007, Whitesides who first proposed the modern system for the PDA
used photolithography to create the hydrophilic/hydrophobic contrast on a
chromatography paper.4 In this treatment, UV-sensitive polymer photoresist
(SU-8 2010) was soaked in a chromatography paper and then polymerized by
UV light through a photomask. After the uncured photoresist was removed
with a proper solvent, the resultant hydrophobic polymer walls act as a
chemical-resistant barriers within it a trace amount of urine solution containing
protein and glucose flows to the test areas for biological assays. ...

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Acknowledgements

I would like to express my sincere gratitude to Professor Shoji Ishizaka,

my supervisor for his patient guidance, invaluable suggestion, helpful

discussion and encouragement for three years. I would like to express my deep

gratitude to Associate Professor Hiroki Matsubara for the guidance and

priceless discussion and encouragement throughout my research. I would like

to thank Yuta Tanaka who helped me so much in my experiments. And I also

would like to thank all members in analytical chemistry for their help

I would like to express my special thanks to my parents, my wife and my

son in Vietnam for their sacrifices and encouragement through the period of

time that I researched in Japan.

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Supporting Information

Figure S1 Photolysis of triphenylsulfonium salts

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