Effects of neuropsychiatric symptoms of dementia on reductions in activities of daily living in patients with Alzheimer's disease

1 McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer’s disease: report of NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s Disease. Neurology 1984; 34: 939-944.

2 Perry RJ, Watson P, Hodge JR. The nature and staging of attention dysfunction in early (minimal and mild) Alzheimer’s disease: relationship to episodic and semantic memory impairment. Neuropsychologia 2000; 38: 252-271.

3 Baudic S, Barba GD, Thibaudet MC, Smagghe A, Remy P, Traykov L. Executive function deficit in early Alzheimer’s disease and their relations with episodic memory. Arch Clin Neuropsychol 2006; 21: 15-21.

4 Perry RJ, Hodges JR. Relationship between functional and neuropsychological performance in early Alzheimer disease. Alzheimer Dis Assoc Disord 2000; 14: 1-10.

5 Kamiya M, Osawa A, Kondo I, Sakurai T. Factors associated with cognitive function that cause a decline in the level of activities of daily living in Alzheimer’s disease. Geriatr Gerontol Int 2018; 18:50-56.

6 Martyr A, Clare L. Executive function and activities of daily living in Alzheimer's disease: a correlational meta-analysis. Dement Geriatr Cogn Disord 2012; 33: 189-203.

7 Roy S, Ficarro S, Duberstein P et al. Executive Function and Personality Predict Instrumental Activities of Daily Living in Alzheimer Disease. Am J Geriatr Psychiatry 2016; 24: 1074-1083.

8 Mega MS, Cummings JL, Fiorello T, Gornbein J. The spectrum of behavioral changes in Alzheimer's disease. Neurology 1996; 46: 130-135.

9 Donaldson C, Tarrier N, Burns A. The impact of the symptoms of dementia on caregivers. Br J Psychiatry 1997; 170: 62-68.

10 Geda YE, Schneider LS, Gitlin LN et al. Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement 2013; 9: 602- 608.

11 Nagata T, Nakajima S, Shinagawa S et al. Psychosocial or clinico-demographic factors related to neuropsychiatric symptoms in patients with Alzheimer's disease needing interventional treatment: analysis of the CATIE-AD study. Int J Geriatr Psychiatry 2017; 32: 1264-1271.

12 Nagata T, Nakajima S, Shinagawa S et al. Baseline Predictors of Antipsychotic Treatment Continuation and Response at Week 8 in Patients with Alzheimer's Disease with Psychosis or Aggressive Symptoms: An Analysis of the CATIE-AD Study. J Alzheimers Disease 2017; 60: 263-272.

13 Nagata T, Ishii K, Ito T et al. Correlation between a reduction in Frontal Assessment Battery scores and delusional thoughts in patients with Alzheimer’s disease. Psychiatry Clin Neurosci 2009; 63: 449-454.

14 Nagata T, Shinagawa S, Ochiai Y et al. Relationship of frontal lobe dysfunction and aberrant motor behaviors in patients with Alzheimer's disease. Int Psychogeriatr 2010; 22: 463-469.

15 Harwood DG, Barker WW, Ownby RL, Duara R. Relationship of behavioral and psychological symptoms to cognitive impairment and functional status in Alzheimer’s disease. Int J Geriatr Psychiatry 2000; 15: 393-400.

16 Mok WY, Chu LW, Chung CP, Chan NY, Hui SL. The relationship between non- cognitive symptoms and functional impairment in Alzheimer's disease. Int J Geriatr Psychiatry 2004; 19: 1040-1046.

17 Okura T, Plassman BL, Steffens DC, Llewellyn DJ, Potter GG, Langa KM. Prevalence of neuropsychiatric symptoms and their association with functional limitations in older adults in the United States: the aging, demographics, and memory study. J Am Geriatr Soc 2010; 58: 330-337.

18 Wadsworth LP, Lorius N, Donovan NJ et al. Neuropsychiatric symptoms and global functional impairment along the Alzheimer's continuum. Dement Geriatr Cogn Disord 2012; 34: 96-111.

19 Peters ME, Schwartz S, Han D et al. Neuropsychiatric symptoms as predictors of progression to severe Alzheimer's dementia and death: The Cache County Dementia Progression Study. Am J Psychiatry 2015; 172: 460-465.

20 Poulin SP, Bergeron D, Dickerson BC, Alzheimer’s Disease Neuroimaging Initiative. Risk Factors, Neuroanatomical Correlates, and Outcome of Neuropsychiatric Symptoms in Alzheimer's Disease. J Alzheimers Dis 2017; 60: 483-493.

21 Folstein MF, Folstein SE, McHugh PR. “Mini-Mental State” . A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189- 198.

22 Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry 1982; 140: 566-572.

23 Reisberg B, Borenstein J, Salob S P, Ferris SH, Franssen E, Georgotas A. (1987) Behavioral symptoms in Alzheimer’s disease: phenomenology and treatment. J Clin Psychiatry 1987; 48 (5 Suppl.): 9–15.

24 Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969; 9: 179-186.

25 Ju YE, Lucey BP, Holtzman DM. Sleep and Alzheimer disease pathology-a bidirectional relationship. Nat Rev Neurol 2014; 10: 115-119.

26 Jacobs HI, Gronenschild EH, Evers EA et al. Visuospatial processing in early Alzheimer's disease: a multimodal neuroimaging study. Cortex 2015; 64: 394-406.

27 D’Onofrio G, Sancarlo D, Panza F et al. Neuropsychiatric symptoms and functional status in Alzheimer’s disease and vascular dementia patients. Curr Alzheimer Res 2012; 9: 759-71.