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書き出し
Design and synthesis of the novel orexin receptor ligands with 1,3,5-trioxazatriquinane skeleton
概要
1.1 Screening for drug discovery and chemical library
Hit identification is the first crucial step for successful drug development, which can generally take more
than 10 years from target validation to its approval (Figure 1).1 This process identifies the right small molecules,
also called hits or hit compounds that bind to the target and induce the desired activity. High-quality starting
hits can be expected to increase the efficiency of the hit identification process consequently the entire drug
discovery project. ...
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