リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

リケラボ 全国の大学リポジトリにある学位論文・教授論文を一括検索するならリケラボ論文検索大学・研究所にある論文を検索できる

大学・研究所にある論文を検索できる 「Molecular genetic studies on leaf development in Oryza sativa」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。
リケラボ

コピーが完了しました

URLをコピーしました

論文の公開元へ論文の公開元へ
書き出し

Molecular genetic studies on leaf development in Oryza sativa

松本, 光梨 東京大学 DOI:10.15083/0002004769

2022.06.22

概要

Leaves are important for photosynthesis and show diverse morphology in angiosperms. Although molecular genetic mechanism underlying leaf morphogenesis have been understood deeply in eudicots such as Arabidopsis thaliana, the knowledge of leaf development in monocots is still insufficient. In this dissertation, I focused on two curling leaf mutants, curled later1 (cul1) and halfpipe-like leaf1 (hal1), in order to get new insights for leaf development in a model monocot, Oryza sativa (rice). In chapter 2, I revealed that CUL1 encoding a large subunit of Elongator complex is required for leaf development at late stage of vegetative phase and for proper maintenance of the shoot apical meristem (SAM). In chapter 3, I characterized the leaf phenotype of hal1.

CURLED LATER1 encoding the largest subunit of the Elongator complex has a unique role in rice development

In chapter 2, I first characterized the cul1 mutant with narrow and curled leaves. By histological analysis, I revealed that the development of both the bulliform cells and sclerenchyma cells were impaired in cul1 leaves and that these defects were a cause of curling leaf phenotype. These leaf phenotypes were not observed in early-middle stages of the vegetative phase and appeared specifically at late stage. It is therefore likely that cul1 displayed a heteroblastic change. In general, the heteroblastic change is observed in the transition from the juvenile to adult phase in many plants. The heteroblastic change in cul1 was likely to occur at the late adult phase. In this sense, the CUL1 seems to play a unique role in leaf development in rice.

I also revealed that the SAM was smaller in cul1 than in wild-type, suggesting that CUL1 function is associated with meristem activity to some extent. Consistent with this, the leaf initiation rate was slow in cul1, as compared with wild-type. Unlike leaf phenotype, the partial defect in the SAM appeared independently of growth stage. I also suggested that the appearance of leaf phenotype at the late adult phase seems to be associated with the transition of meristem fate, that is, from the vegetative meristem to the reproductive meristem.

I revealed that CUL1 encodes a yeast ELP1-like protein, which is the largest subunit of the Elongator complex. Elongator is conserved in eukaryotes such as yeast, animals and plants, whereas its roles are diversified among various organisms. In Arabidopsis, Elongator is known to regulate leaf and root development, hormone action and environmental responses. In other plant, however, the function of Elongator complex is still largely unknown. To get further evidence that Elongator is required for rice development, I disrupted OsELP3 encoding the catalytic subunit of the Elongator complex by CRISPR-Cas9 technology. Knockout lines of OsELP3 produced curled narrow leaves with impaired bulliform and sclerenchyma cells, similar to the cul1 mutant. In addition, the curled narrow leaf phenotype appeared at late stage of the vegetative phase. Therefore, these results confirm the importance of Elongator activity in normal leaf development at later vegetative phase in rice. Furthermore, this result showing that the cul1 mutant and OsELP3 knockout line shared mutant phenotypes suggests that the proteins encoding by these two genes act together as a component of the Elongator complex.

To explore the effect of the cul1 mutation on gene expression, I carried out transcriptome analysis. As a result, the genes involved in protein quality control, such as ubiquitin-associated protein degradation and molecular chaperon, were highly upregulated specifically in the cul1 shoot apex at the later vegetative phase (cul-L shoot apex). This result suggests that the genes responsible for protein quality control is induced by the accumulation of abnormal proteins in the cul1-L apex probably due to the loss of Elongator activity. Therefore, it seems likely that the Elongator is required for the protein progression of translational processes. The defects in leaf development in cul1 might be related to the impaired translation of the proteins, which plays essential roles in the differentiation of bulliform and sclerenchyma cells.

Characterization of half-pipe-like leaf1 mutant that exhibit curled leaf phenotype

In chapter 3, I focused on a semi-dominant mutant, hal1-d, which produced the adaxially curled leaves. Histological analysis revealed that the bulliform cells of hal1-d leaf were small and abnormal shape. The obseversion of semi-transparent leaves by TOMEI methods showed that the bulliform cell files were often indistinguishable from other cell files in hal1-d, suggesting that the bulliform cells were failed to growth. Therefore, the defective development of the bulliform cells were likely to be a main cause of curling leaf phenotype in hal1-d mutant. The size of the leaf blade and the spikelet were also influenced by the hal1-d mutation.

Conclusion and perspectives
The Elongator complex plays multiple roles in diverse organisms. The loss-of-function of the genes encoding Elongator subunit exhibits various phenotypes depending on diverse species. In addition, the studies on Elongator have not yet reported in plants, except for Arabidopsis. In this dissertation, I revealed that the Elongator complex is required for leaf development and meristem activity, and associated with heteroblasty in rice. The role of Elongator in rice development seems to be different from that of Elongator in Arabidopsis development to some extent. Therefore, the function of Elongator is likely to have been diversified even within angiosperms. Further studies on Elongator in rice would be expected to provide important information on not only elucidation of leaf and meristem development in rice but also the conservation and diversification of Elongator function in angiosperms

論文の公開元へ

この論文で使われている画像

関連論文

関連論文をもっと見る

参考文献

Abe A, Kosugi S, Yoshida K, Natsume S, Takagi H, Kanzaki H, Matsumura H, Yoshida K, Mitsuoka C, Tamiru M, Innan H, Cano L, Kamoun S, Terauchi R (2012) Genome sequencing reveals agronomically important loci in rice using MutMap. Nat. Biotechnol. 30: 174-178

Abe M, Yoshikawa T, Nosaka M, Sakakibara H, Sato Y, Nagato Y, Itoh J-I (2010) WAVY LEAF1, an ortholog of Arabidopsis HEN1, regulates shoot development by maintaining MicroRNA and trans-acting small interfering RNA accumulation in rice. Plant Physiol. 154: 1335-1346

Aichinger E, Kornet N, Friedrich T, Laux T (2012) Plant stem cell niches. Annu. Rev. Plant Biol. 63: 615-636

Bowman, JL (2000) The YABBY gene family and abaxial cell fate. Curr. Opin. in Plant Biol. 3: 17-22

Byrne ME, Barley R, Curtis M, Arroyo JM, Dunham, M, Hudson A, Martienssen RA (2000) Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis. Nature 408: 967-971 Chitwood DH, Sinha NR (2016) Evolutionary and environmental forces sculpting leaf development. Curr. Biol. 26: R297-R306

Chitwood DH, Guo M, Nogueira FT, Timmermans MC (2007) Establishing leaf polarity: the role of small RNAs and positional signals in the shoot apex. Development 134: 813-823

Cho SH, Yoo SC, Zhang H, Lim JH, Paek NC (2014) Rice NARROW LEAF1 Regulates Leaf and Adventitious Root Development. Plant Mol. Biol. Rep. 32: 270-281

Cho SH, Yoo SC, Zhang H, Pandeya D, Koh HJ, Hwang JY, Kim GT, Paek NC (2013) The rice narrow leaf2 and narrow leaf3 loci encode WUSCHEL-related homeobox 3A (OsWOX3A) and function in leaf, spikelet, tiller and lateral root development. New Phytol. 198: 1071-1084

Chuck G, Cigan AM, Saeteurn K, Hake S (2007) The heterochronic maize mutant

Corngrass1 results from overexpression of a tandem microRNA. Nature Genet. 39: 544-549

Dalwadi U, Yip CK (2018) Structural insights into the function of Elongator. Cell Mol. Life Sci. 75: 1613-1622

Debernardi JM, Mecchia MA, Vercruyssen L, Smaczniak C, Kaufmann K, Inze D, Rodriguez RE, Palatnik JF (2014) Post-transcriptional control of GRF transcription factors by microRNA miR396 and GIF co-activator affects leaf size and longevity. Plant J. 79: 413-426

Ding Y, Mou Z (2015) Elongator and its epigenetic role in plant development and responses to abiotic and biotic stresses. Front. Plant Sci. 6: 296

Disch S, Anastasiou E, Sharma VK, Laux T, Fletcher JC, Lenhard M (2006) The E3 ubiquitin ligase BIG BROTHER controls Arabidopsis organ size in a dosagedependent manner. Curr. Biol. 16: 272-279

Emery JF, Floyd SK, Alvarez J, Eshed Y, Hawker NP, Izhaki A, Baum SF, Bowman JL (2003) Radial Patterning of Arabidopsis Shoots by Class III HD-ZIP and KANADI Genes. Curr. Biol. 13: 1768-1774

Fang X, Cui Y, Li Y, Qi Y (2015) Transcription and processing of primary microRNAs are coupled by Elongator complex in Arabidopsis. Nat. Plants 1: 15075

Fujino K, Matsuda Y, Ozawa K, Nishimura T, Koshiba T, Fraaije MW, Sekiguchi H (2008) NARROW LEAF 7 controls leaf shape mediated by auxin in rice. Mol.

Genet. Genomics 279: 499-507 Glatt S, Muller CW (2013) Structural insights into Elongator function. Curr. Opin. Struct. Biol. 23: 235-242

Hasegawa J, Sakamoto Y, Nakagami S, Aida M, Sawa S, Matsunaga S (2016) Three-dimensional imaging of plant organs using a simple and rapid transparency technique. Plant Cell Physiol. 57: 462-472

Hibara K-I, Isono M, Mimura M, Sentoku N, Kojima M, Sakakibara H, Kitomi Y, Yoshikawa T, Itoh J-I, Nagato Y (2016) Jasmonate regulates juvenile-to-adult phase transition in rice. Development 143: 3407-3416

Hibara K-I, Obara M, Hayashida E, Abe M, Ishimaru T, Satoh H, Itoh J-I, Nagato Y (2009) The ADAXIALIZED LEAF1 gene functions in leaf and embryonic pattern formation in rice. Dev. Biol. 334: 345-354

Hiei Y, Ohta S, Komari T, Kumashiro T (1994) Efficient transformation of rice (Oryza sativa L.) mediated by Agrobacterium and sequence analysis of the boundaries of the T-DNA. Plant J. 6: 271-282

Honda E, Yew CL, Yoshikawa T, Sato Y, Hibara K-I, Itoh J-I (2018) LEAF LATERAL SYMMETRY1, a Member of the WUSCHEL-RELATED HOMEOBOX3 Gene Family, Regulates Lateral Organ Development Differentially from Other Paralogs, NARROW LEAF2 and NARROW LEAF3 in Rice. Plant Cell Physiol. 59:376-391

Horiguchi G, Kim GT, Tsukaya H (2005) The transcription factor AtGRF5 and the transcription coactivator AN3 regulate cell proliferation in leaf primordia of Arabidopsis thaliana. Plant J. 43: 68-78

Hu J, Zhu L, Zeng D, Gao Z, Guo L, Fang Y, Zhang G, Dong G, Yan M, Liu J, Qian Q (2010) Identification and characterization of NARROW AND ROLLED LEAF 1, a novel gene regulating leaf morphology and plant architecture in rice. Plant Mol. Biol. 73: 283-292

Huijser P, Schmid M (2011) The control of developmental phase transitions in plants. Development 138: 4117-4129

Hunter C, Willmann MR, Wu G, Yoshikawa M, de la Luz Gutierrez-Nava M, Poethig SR (2006) Trans-acting siRNA-mediated repression of ETTIN and ARF4 regulates heteroblasty in Arabidopsis. Development 133: 2973-2981

Husbands AY, Chitwood DH, Plavskin Y, Timmermans MC (2009) Signals and prepatterns: new insights into organ polarity in plants. Genes Dev. 23: 1986-1997

Ishiwata A, Ozawa M, Nagasaki H, Kato M, Noda Y, Yamaguchi T, Nosaka M, Shimizu-Sato S, Nagasaki A, Maekawa M, Hirano H-Y, Sato Y (2013) Two WUSCHEL-related homeobox genes, narrow leaf2 and narrow leaf3, control leaf width in rice. Plant Cell Physiol. 54: 779-792

Itoh J-I, Nonomura K-I, Ikeda K, Yamaki S, Inukai Y, Yamagishi H, Kitano H, Nagato Y (2005) Rice plant development: from zygote to spikelet. Plant Cell Physiol. 46: 23-47

Itoh J-I, Sato Y, Nagato Y (2008) The SHOOT ORGANIZATION2 gene coordinates leaf domain development along the central-marginal axis in rice. Plant Cell Physiol. 49: 1226-1236

Kerstetter RA, Bollman K, Taylor RA, Bomblies K, Poethig RS (2001) KANADI regulates organ polarity in Arabidopsis. Nature 411: 706-709

Kerstetter RA, Poethig RS (1998) The specification of leaf identity during shoot development. Annu. Rev. Plant Biol. 14: 373-398

Kim D, Langmead B, Salzberg SL (2015) HISAT: a fast spliced aligner with low memory requirements. Nat. Methods 12: 357-360

Kim GT, Tsukaya H, Uchimiya H (1998) The ROTUNDIFOLIA3 gene of Arabidopsis thaliana encodes a new member of the cytochrome P-450 family that is required for the regulated polar elongation of leaf cells. Genes Dev. 12: 2381-2391

Kim JH, Tsukaya H (2015) Regulation of plant growth and development by the GROWTH-REGULATING FACTOR and GRF-INTERACTING FACTOR duo. J. Exp. Bot. 66: 6093-6107

Kim, JH, Kende H (2004) A transcriptional coactivator, AtGIF1, is involved in regulating leaf growth and morphology in Arabidopsis. Proc. Natl. Acad. Sci. USA 101: 13374-13379

Kojima S, Iwasaki M, Takahashi H, Imai T, Matsumura Y, Fleury D, Van Lijsebettens M, Machida Y, Machida C (2011) Asymmetric leaves2 and Elongator, a histone acetyltransferase complex, mediate the establishment of polarity in leaves of Arabidopsis thaliana. Plant Cell Physiol. 52: 1259-1273

Kubo FC, Yasui Y, Kumamaru T, Sato Y, Hirano H-Y (2016) Genetic analysis of rice mutants responsible for narrow leaf phenotype and reduced vein number. Genes Genet. Syst. 91: 235-240

Kubo FC, Yasui Y, Ohmori Y, Kumamaru T, Tanaka W, Hirano H-Y (2019) DWARF WITH SLENDER LEAF1 encoding a histone deacetylase plays diverse roles in rice developmen. Plant Cell Physiol. (in press)

Kuhlemeier C, Timmermans MC (2016) The Sussex signal: insights into leaf dorsiventrality. Development 143: 3230-3237

Kumar S, Stecher G, Tamura K (2016) MEGA7: Molecular evolutionary genetics analysis version 7.0 for bigger datasets. Mol. Biol. Evol. 33: 1870-1874

Lauter N, Kampani A, Carlson S, Goebel M, Moose SP (2005) microRNA172 downregulates glossy15 to promote vegetative phase change in maize. Proc. Natl. Acad. Sci. USA 102: 9412-9417

Leitner J, Retzer K, Malenica N, Bartkeviciute R, Lucyshyn D, Jager G, Korbei B, Bystrom A, Luschnig C (2015) Meta-regulation of Arabidopsis auxin responses depends on tRNA maturation. Cell Rep. 11: 516-526

Leyser O, Day S (2003) Mechanisms in plant development. John Wiley & Sons

Li M, Xiong G, Li R, Cui J, Tang D, Zhang B, Pauly M, Cheng Z, Zhou Y (2009) Rice cellulose synthase-like D4 is essential for normal cell-wall biosynthesis and plant growth. Plant J. 60: 1055-1069

Liao Y, Smyth GK, Shi W (2014) featureCounts: an efficient general purpose program for assigning sequence reads to genomic features. Bioinformatics 30: 923-930

Long JA, Moan EI, Medford JI, Barton MK (1996) A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis. Nature 379: 66-69

Malenica N, Abas L, Benjamins R, Kitakura S, Sigmund HF, Jun KS, Hauser MT, Friml J, Luschnig C (2007) MODULATOR OF PIN genes control steady-state levels of Arabidopsis PIN proteins. Plant J. 51: 537-550

Matsumoto H, Yasui Y, Kumamaru T, Hirano H-Y (2017) Characterization of a halfpipe-like leaf1 mutant that exhibits a curled leaf phenotype. Genes Genet. Syst. 92: 287-291

McConnell JR., Emery J, Eshed Y, Bao N, Bowman J, Barton MK (2001) Role of PHABULOSA and PHAVOLUTA in determining radial patterning in shoots. Nature 411: 709-713

Mehlgarten C, Jablonowski D, Wrackmeyer U, Tschitschmann S, Sondermann D, Jager G, Gong Z, Bystrom AS, Schaffrath R, Breunig KD (2010) Elongator function in tRNA wobble uridine modification is conserved between yeast and plants. Mol. Microbiol. 76: 1082-1094

Mikami M, Toki S, Endo M (2015) Comparison of CRISPR/Cas9 expression constructs for efficient targeted mutagenesis in rice. Plant Mol. Biol. 88: 561-572

Moose SP, Sisco PH (1996) Glossy15, an APETALA2-like gene from maize that regulates leaf epidermal cell identity. Genes Dev. 10: 3018-3027

Narita NN, Moore S, Horiguchi G, Kubo M, Demura T, Fukuda H, Goodrich J, Tsukaya H (2004) Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell proliferation and alters leaf shape in Arabidopsis thaliana. Plant J. 38: 699-713

Nelissen H, De Groeve S, Fleury D, Neyt P, Bruno L, Bitonti MB, Vandenbussche F, Van der Straeten D, Yamaguchi T, Tsukaya H, Witters E, De Jaeger G, Houben A, Van Lijsebettens M (2010) Plant Elongator regulates auxin-related genes during RNA polymerase II transcription elongation. Proc. Natl. Acad. Sci. USA 107: 1678-1683

Nelissen H, Fleury D, Bruno L, Robles P, De Veylder L, Traas J, Micol JL, Van Montagu M, Inze D, Van Lijsebettens M (2005) The elongata mutants identify a functional Elongator complex in plants with a role in cell proliferation during organ growth. Proc. Natl. Acad. Sci. USA 102: 7754-7759

Obara M, Ikeda K, Itoh J-I, Nagato Y (2004) Characterization of leaf lateral symmetry 1 Mutant in Rice. Breed. Sci. 54: 157-163

Ohmori Y, Abiko M, Horibata A, Hirano H-Y (2008) A transposon, Ping, is integrated into intron 4 of the DROOPING LEAF gene of rice, weakly reducing its expression, and causing a mild drooping leaf phenotype. Plant Cell Physiol. 49:1176-1184

Ohmori Y, Toriba T, Nakamura H, Ichikawa H, Hirano H-Y (2011) Temporal and spatial regulation of DROOPING LEAF gene expression that promotes midrib formation in rice. Plant J. 65: 77-86

Ori N, Eshed Y, Chuck G, Bowman JL, Hake S (2000) Mechanisms that control knox gene expression in the Arabidopsis shoot. Development 127: 5523-5532

Otero G, Fellows J, Li Y, de Bizemont T, Dirac AM, Gustafsson CM, ErdjumentBromage H, Tempst P, Svejstrup JQ (1999) Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation. Mol. Cell 3: 109-118

Pekker I, Alvarez JP, Eshed Y (2005) Auxin response factors mediate Arabidopsis organ asymmetry via modulation of KANADI activity. Plant Cell 17: 2899-2910

Qi J, Qian Q, Bu Q, Li S, Chen Q, Sun J, Liang W, Zhou Y, Chu C, Li X, Ren F, Palme K, Zhao B, Chen J, Chen M, Li C (2008) Mutation of the rice Narrow leaf1 gene, which encodes a novel protein, affects vein patterning and polar auxin transport. Plant Physiol. 147: 1947-1959

Qi L, Zhang X, Zhai H, Liu J, Wu F, Li C, Chen Q (2019) Elongator is required for root stem cell maintenance by regulating SHORTROOT transcription. Plant Physiol. 179: 220-232

Risso D, Ngai J, Speed TP, Dudoit S (2014) Normalization of RNA-seq data using factor analysis of control genes or samples. Nat. Biotechnol. 32: 896-902

Satoh H, Matsusaka H, Kumamaru T (2010) Use of N-methyl-N-nitrosourea treatment of fertilized egg cells for saturation mutagenesis of rice. Breed. Sci. 60: 475-485

Sentoku N, Sato Y, Kurata N, Ito Y, Kitano H, Matsuoka M (1999) Regional expression of the rice KN1-type homeobox gene family during embryo, shoot, and flower development. Plant Cell 11: 1651-1664

Sessions A, Nemhauser JL, McColl A, Roe JL, Feldmann KA, Zambryski PC (1997) ETTIN patterns the Arabidopsis floral meristem and reproductive organs. Development 124: 4481-4491

Siegfried KR, Eshed Y, Baum SF, Otsuga D, Drews GN, Bowman JL (1999) Members of the YABBY gene family specify abaxial cell fate in Arabidopsis. Development 126: 4117-4128

Sussex, IM (1951) Experiments on the cause of dorsiventrality in leaves. Nature 167: 651-652

Suzuki C, Tanaka W, Hirano H-Y (2019) Transcriptional Corepressor ASP1 and CLVLike Signaling Regulate Meristem Maintenance in Rice. Plant Physiol. 180: 1520-1534

Svejstrup JQ (2007) Elongator complex: how many roles does it play? Curr. Opin. Cell Biol. 19: 331-336

Tanaka N, Itoh H, Sentoku N, Kojima M, Sakakibara H, Izawa T, Itoh J-I, Nagato Y (2011) The COP1 ortholog PPS regulates the juvenile-adult and vegetativereproductive phase changes in rice. Plant Cell 23: 2143-2154

Tanaka W, Toriba T, Hirano H-Y (2017) Three TOB1-related YABBY genes are required to maintain proper function of the spikelet and branch meristems in rice. New Phytol. 215: 825-839

Tanaka W, Toriba T, Ohmori Y, Yoshida A, Kawai A, Mayama-Tsuchida T, Ichikawa H, Mitsuda N, Ohme-Takagi M, Hirano H-Y (2012) The YABBY gene

TONGARI-BOUSHI1 is involved in lateral organ development and maintenance of meristem organization in the rice spikelet. Plant Cell 24: 80-95

Telfer A, Bollman KM, Poethig RS (1997) Phase change and the regulation of trichome distribution in Arabidopsis thaliana. Development 124: 645-654

Toriba T, Hirano H-Y (2018) Two-color in situ hybridization: a technique for simultaneous detection of transcripts from different loci. In N Yamaguchi, ed, Plant

Transcription Factors: Methods and Protocols. Springer New York, New York, NY, pp 269-287

Tsuge T, Tsukaya H, Uchimiya H (1996) Two independent and polarized processes of cell elongation regulate leaf blade expansion in Arabidopsis thaliana (L.) Heynh. Development 122: 1589-1600

Usami T, Horiguchi G, Yano S, Tsukaya H (2009) The more and smaller cells mutants of Arabidopsis thaliana identify novel roles for SQUAMOSA PROMOTER BINDING PROTEIN-LIKE genes in the control of heteroblasty. Development 136: 955-964

Van Lijsebettens M, Grasser KD (2014) Transcript elongation factors: shaping transcriptomes after transcript initiation. Trends Plant Sci. 19: 717-726

Vercruyssen L, Verkest A, Gonzalez N, Heyndrickx KS, Eeckhout D, Han SK, Jegu T, Archacki R, Van Leene J, Andriankaja M, De Bodt S, Abeel T, Coppens F, Dhondt S, De Milde L, Vermeersch M, Maleux K, Gevaert K, Jerzmanowski A, Benhamed M, Wagner D, Vandepoele K, De Jaeger G, Inze D (2014) ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development. Plant Cell 26: 210-229

Versees W, De Groeve S, Van Lijsebettens M (2010) Elongator, a conserved multitasking complex? Mol. Microbiol. 76: 1065-1069

Waites R, Hudson A (1995) phantastica: a gene required for dorsoventrality of leaves in Antirrhinum majus. Development 121: 2143-2154

Waites R, Selvadurai HRN, Oliver, IR, Hudson A (1998) The PHANTASTICA Gene Encodes a MYB Transcription Factor Involved in Growth and Dorsoventrality of Lateral Organs in Antirrhinum. Cell 93: 779-789

Wang JW, Park MY, Wang LJ, Koo Y, Chen XY, Weigel D, Poethig RS (2011) MiRNA control of vegetative phase change in trees. PLoS Genet. 7: e1002012

Wang L, Wang S, Li W (2012) RSeQC: quality control of RNA-seq experiments. Bioinformatics 28: 2184-2185

Wittschieben BO, Otero G, de Bizemont T, Fellows J, Erdjument-Bromage H, Ohba R, Li Y, Allis CD, Tempst P, Svejstrup JQ (1999) A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol. Cell 4: 123-128

Woloszynska M, Gagliardi O, Vandenbussche F, De Groeve S, Alonso Baez L, Neyt P, Le Gall S, Fung J, Mas P, Van Der Straeten D, Van Lijsebettens M (2018) The Elongator complex regulates hypocotyl growth in darkness and during photomorphogenesis. J. Cell Sci. 131: jcs203927

Woloszynska M, Le Gall S, Van Lijsebettens M (2016) Plant Elongator-mediated transcriptional control in a chromatin and epigenetic context. Biochim. Biophys. Acta 1859: 1025-1033

Wu G, Park MY, Conway SR, Wang JW, Weigel D, Poethig RS (2009) The sequential action of miR156 and miR172 regulates developmental timing in Arabidopsis. Cell 138: 750-759

Xu D, Huang W, Li Y, Wang H, Huang H, Cui X (2012) Elongator complex is critical for cell cycle progression and leaf patterning in Arabidopsis. Plant J. 69: 792-808

Yamaguchi T, Nagasawa N, Kawasaki S, Matsuoka M, Nagato Y, Hirano H-Y (2004) The YABBY gene DROOPING LEAF regulates carpel specification and midrib development in Oryza sativa. Plant Cell 16: 500-509

Yan S, Yan CJ, Zeng XH, Yang YC, Fang YW, Tian CY, Sun YW, Cheng ZK, Gu MH (2008) ROLLED LEAF 9, encoding a GARP protein, regulates the leaf abaxial cell fate in rice. Plant Mol. Biol. 68: 239-250

Yasui Y, Ohmori Y, Takebayashi Y, Sakakibara H, Hirano H-Y (2018) WUSCHELRELATED HOMEOBOX4 acts as a key regulator in early leaf development in rice. PLOS Genet. 14: e1007365

Yasui Y, Tanaka W, Sakamoto T, Kurata T, Hirano H-Y (2017) Genetic enhancer analysis reveals that FLORAL ORGAN NUMBER2 and OsMADS3 co-operatively regulate maintenance and determinacy of the flower meristem in rice. Plant Cell Physiol. 58: 893-903

Yoshikawa T, Eiguchi M, Hibara K-I, Ito J-I, Nagato Y (2013) Rice SLENDER LEAF 1 gene encodes cellulose synthase-like D4 and is specifically expressed in M-phase cells to regulate cell proliferation. J. Exp. Bot. 64: 2049-2061

Zhang GH, Xu Q, Zhu XD, Qian Q, Xue HW (2009) SHALLOT-LIKE1 is a KANADI transcription factor that modulates rice leaf rolling by regulating leaf abaxial cell development. Plant Cell 21: 719-735

Zou LP, Sun XH, Zhang ZG, Liu P, Wu JX, Tian CJ, Qiu JL, Lu TG (2011) Leaf rolling controlled by the homeodomain leucine zipper class IV gene Roc5 in rice. Plant Physiol. 156: 1589-1602

参考文献をもっと見る

全国の大学の
卒論・修論・学位論文
を
一発検索！

この論文の関連論文を見る