Saijo-Hamano et al.
vol 5 | no 1 | e202101149
13 of 14
Moore KJ, Webb MR, Eccleston JF (1993) Mechanism of GTP hydrolysis by p21Nras catalyzed by GAP: Studies with a fluorescent GTP analogue.
Biochemistry 32: 7451–7459. doi:10.1021/bi00080a016
Schulte K, Pawlowski N, Faelber K, Frohlich
C, Howard J, Daumke O (2016) The
immunity-related GTPase Irga6 dimerizes in a parallel head-to-head
fashion. BMC Biol 14: 14. doi:10.1186/s12915-016-0236-7
Muftuoglu Y, Xue Y, Gao X, Wu D, Ha Y (2016) Mechanism of substrate
specificity of phosphatidylinositol phosphate kinases. Proc Natl Acad
Sci U S A 113: 8711–8716. doi:10.1073/pnas.1522112113
Steinfeldt T, Konen-Waisman
S, Tong L, Pawlowski N, Lamkemeyer T, Sibley
LD, Hunn JP, Howard JC (2010) Phosphorylation of mouse immunityrelated GTPase (IRG) resistance proteins is an evasion strategy for
virulent Toxoplasma gondii. PLoS Biol 8: e1000576. doi:10.1371/
journal.pbio.1000576
Nitta R, Kikkawa M, Okada Y, Hirokawa N (2004) KIF1A alternately uses two
loops to bind microtubules. Science 305: 678–683. doi:10.1126/
science.1096621
Nitta R, Okada Y, Hirokawa N (2008) Structural model for strain-dependent
microtubule activation of Mg-ADP release from kinesin. Nat Struct Mol
Biol 15: 1067–1075. doi:10.1038/nsmb.1487
Pawlowski N, Khaminets A, Hunn JP, Papic N, Schmidt A, Uthaiah RC, Lange R,
Vopper G, Martens S, Wolf E, et al (2011) The activation mechanism of
Irga6, an interferon-inducible GTPase contributing to mouse
resistance against Toxoplasma gondii. BMC Biol 9: 7. doi:10.1186/17417007-9-7
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC,
Ferrin TE (2004) UCSF Chimera: A visualization system for exploratory
research and analysis. J Comput Chem 25: 1605–1612. doi:10.1002/
jcc.20084
Pradipta A, Sasai M, Motani K, Ma JS, Lee Y, Kosako H, Yamamoto M (2021) Cellautonomous Toxoplasma killing program requires Irgm2 but not its
microbe vacuolar localization. Life Sci Alliance 4: e202000960.
doi:10.26508/lsa.202000960
Saeij JP, Frickel EM (2017) Exposing Toxoplasma gondii hiding inside the
vacuole: A role for GBPs, autophagy and host cell death. Curr Opin
Microbiol 40: 72–80. doi:10.1016/j.mib.2017.10.021
Sasai M, Pradipta A, Yamamoto M (2018) Host immune responses to
Toxoplasma gondii. Int Immunol 30: 113–119. doi:10.1093/intimm/
dxy004
Scharton-Kersten TM, Yap G, Magram J, Sher A (1997) Inducible nitric oxide is
essential for host control of persistent but not acute infection with
the intracellular pathogen Toxoplasma gondii. J Exp Med 185:
1261–1273. doi:10.1084/jem.185.7.1261
Structural mechanism of PVM recognition by Irgb6
Saijo-Hamano et al.
Vagin AA, Steiner RA, Lebedev AA, Potterton L, McNicholas S, Long F,
Murshudov GN (2004) REFMAC5 dictionary: Organization of prior
chemical knowledge and guidelines for its use. Acta Crystallogr D Biol
Crystallogr 60: 2184–2195. doi:10.1107/S0907444904023510
Wittinghofer A, Scheffzek K, Ahmadian MR (1997) The interaction of Ras with
GTPase-activating proteins. FEBS Lett 410: 63–67. doi:10.1016/s00145793(97)00321-9
Winn MD, Ballard CC, Cowtan KD, Dodson EJ, Emsley P, Evans PR, Keegan RM,
Krissinel EB, Leslie AG, McCoy A, et al (2011) Overview of the CCP4 suite
and current developments. Acta Crystallogr D Biol Crystallogr 67:
235–242. doi:10.1107/S0907444910045749
Yamamoto M, Okuyama M, Ma JS, Kimura T, Kamiyama N, Saiga H, Ohshima J,
Sasai M, Kayama H, Okamoto T, et al (2012) A cluster of interferonγ-inducible p65 GTPases plays a critical role in host defense against
Toxoplasma gondii. Immunity 37: 302–313. doi:10.1016/j.immuni.
2012.06.009
Yamashita K, Hirata K, Yamamoto M (2018) KAMO: Towards automated data
processing for microcrystals. Acta Crystallogr D Struct Biol 74: 441–449.
doi:10.1107/S2059798318004576
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