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Study of a novel resin cement containing anti-microbial compound CPC-Montmorillonite

山本, 裕也 北海道大学

2021.03.25

概要

Objective: The aim of this study was to evaluate the mechanical property, bonding performance and anti-microbial activity of a novel resin cement containing montmorillonite modified Cetylpyridinium chloride (CPC-Mont), and to determine the optimal particle size and concentration of CPC-Mont to be lorded to the resin cement.

Materials and methods: Montmorillonite filler modified CPC with a median diameter of 30μm and 7μm were prepared, and they lorded to a resin cement at concentrations of 2, 3, 4, 5,7.5 wt.%. Mechanical property and bonding performance of the resin cements were evaluated by 3 point bending test and micro-tensile bond strength test. The amount of CPC released from the resin disks were quantified using a UV-vis recording spectrophotometer. The anti-biofilm activity was also studied using scanning electron microscope.

Results: Mechanical property and bonding performance of the resin cement decreased with lording 30μm CPC-Mont, but no reduction was observed with lording 7μm CPC-Mont. Although CPC release was decreased as the immersion period passed, 5 and 7.5 wt.% CPC-Mont resin cement inhibited biofilm formation for 30 days.

Conclusions: The lording of CPC-Mont with a median diameter of 7μm at concentrations of 5 to 7.5 wt.% to resin cement was effective in achieving continuous anti-biofilm activity while maintaining the mechanical property and bonding performance.

Keywords: Secondary caries, Biofilm, Resin cement, Montmorillonite, Cetylpyridinium chloride

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