1. Lim, E. K. Plant glycosyltransferases: Their potential as novel biocatalysts. Chem. - A Eur. J. 11, 5486–5494 (2005).
2. Caputi, L., Malnoy, M., Goremykin, V., Nikiforova, S. & Martens, S. A genome-wide phylogenetic reconstruction of family 1 UDP- glycosyltransferases revealed the expansion of the family during the adaptation of plants to life on land. Plant J. 69, 1030–1042 (2012).
3. Gachon, C. M. M., Langlois-Meurinne, M. & Saindrenan, P. Plant secondary metabolism glycosyltransferases: The emerging functional analysis. Trends Plant Sci. 10, 542–549 (2005).
4. Kleczkowski, K., Schell, J. & Bandur, R. Phytohormone conjugates: Nature and function. CRC. Crit. Rev. Plant Sci. 14, 283–298 (1995).
5. Rea, P. MRP subfamily ABC transporters from plants and yeast. J. Exp. Bot. 50, 895–913 (1999).
6. Messner, B., Thulke, O. & Schäffner, A. R. Arabidopsis glucosyltransferases with activities toward both endogenous and xenobiotic substrates. Planta 217, 138–146 (2003).
7. Taguchi, G., Yazawa, T., Hayashida, N. & Okazaki, M. Molecular cloning and heterologous expression of novel glucosyltransferases from tobacco cultured cells that have broad substrate specificity and are induced by salicylic acid and auxin. 4094, 4086–4094 (2001).
8. Kaminaga, Y., Sahin, F. P. & Mizukami, H. Molecular cloning and characterization of a glucosyltransferase catalyzing glucosylation of curcumin in cultured Catharanthus roseus cells. FEBS Lett. 567, 197–202 (2004).
9. Cui, L. et al. Identification of UDP-glycosyltransferases involved in the biosynthesis of astringent taste compounds in tea (Camellia sinensis). J. Exp. Bot. 67, 2285–2297 (2016).
10. K.K Makinen, E. S. A quantitative study of mannitol, sorbitol, xylitol, and xylose in wild berries and commercial fruits. J. Food Sci. 45, 367–371 (1980).
11. Basu, A., Nguyen, A., Betts, N. M. & Lyons, T. J. Strawberry as a functional food: An evidence- based review. Crit. Rev. Food Sci. Nutr. (2014). doi:10.1080/10408398.2011.608174
12. DSファーマアニマルヘルス プレスリリース 2014年3月24日.
13. Mayerl, F., Näf, R. & Thomas, A. F. 2,5-Dimethyl-4-hydroxy-3(2H)-furanone glucoside: Isolation from strawberries and synthesis. Phytochemistry 28, 631–633 (1989).
14. Ubeda, C. et al. Glycosidically bound aroma compounds and impact odorants of four strawberry varieties. J. Agric. Food Chem. 60, 6095–6102 (2012).
15. Tokitomo, Y., Steinhaus, M., Büttner, A. & Schieberle, P. Odor-active constituents in fresh pineapple (Ananas comosus [L.] Merr.) by quantitative and sensory evaluation. Biosci. Biotechnol. Biochem. 69, 1323–30 (2005).
16. Janeš, D., Kantar, D., Kreft, S. & Prosen, H. Identification of buckwheat (Fagopyrum esculentumMoench) aroma compounds with GC-MS. Food Chem. 112, 120–124 (2009).
17. Buttery, R. G., Takeoka, G. R., Naim, M., Rabinowitch, H. & Nam, Y. Analysis of furaneol in tomato using dynamic headspace sampling with sodium sulfate. J. Agric. Food Chem. 49, 4349– 4351 (2001).
18. Raab, T. et al. FaQR, required for the biosynthesis of the strawberry flavor compound 4-hydroxy- 2,5-dimethyl-3(2H)-furanone, encodes an enone oxidoreductase. Plant Cell 18, 1023–1037 (2006).
19. Klein, D., Fink, B., Arold, B., Eisenreich, W. & Schwab, W. Functional characterization of enone oxidoreductases from strawberry and tomato fruit. J. Agric. Food Chem. 55, 6705–6711 (2007).
20. Schwab, W. Natural 4-hydroxy-2,5-dimethyl-3(2H)-furanone (Furaneol®). Molecules 18, 6936–51 (2013).
21. Roscher, R., Herderich, M., Steffen, J. P., Schreier, P. & Schwab, W. 2,5-Dimethyl-4-hydroxy- 3[2H]-furanone 6’ O -malonyl-β-D-glucopyranoside in strawberry fruits. Phytochemistry 43, 155– 9 (1996).
22. Lunkenbein, S. et al. Cinnamate metabolism in ripening fruit. Characterization of a UDP-glucose: Cinnamate glucosyltransferase from strawberry. Plant Physiol. 140, 1047–1058 (2006).
23. Griesser, M. et al. Redirection of flavonoid biosynthesis through the down-regulation of an anthocyanidin glucosyltransferase in ripening strawberry fruit. Plant Physiol. 146, 1528–1539 (2008).
24. Landmann, C., Fink, B. & Schwab, W. FaGT2: A multifunctional enzyme from strawberry (Fragaria x ananassa) fruits involved in the metabolism of natural and xenobiotic compounds. Planta 226, 417–428 (2007).
25. Griesser, M. et al. Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle. J. Exp. Bot. 59, 2611–25 (2008).
26. Song, C. et al. Glucosylation of 4-hydroxy-2,5-dimethyl-3(2H)-furanone, the key strawberry flavor compound in strawberry fruit. Plant Physiol. 171, 139–151 (2016).
27. Hirakawa, H. et al. Dissection of the octoploid strawberry genome by deep sequencing of the genomes of fragaria species. DNA Res. 21, 169–181 (2014).
28. Sasaki, K., Takase, H., Kobayashi, H., Matsuo, H. & Takata, R. Molecular cloning and characterization of UDP-glucose: furaneol glucosyltransferase gene from grapevine cultivar Muscat Bailey A (Vitis labrusca × V. vinifera). J. Exp. Bot. 66, 6167–74 (2015).
29. Song, C. et al. A UDP-glucosyltransferase functions in both acylphloroglucinol glucoside and anthocyanin biosynthesis in strawberry (Fragaria × ananassa). Plant J. 85, 730–742 (2016).
30. Ohgami, S. et al. Volatile glycosylation in tea plants: Sequential glycosylations for the biosynthesis of aroma β -primeverosides are catalyzed by two Camellia sinensis glycosyltransferases. Plant Physiol. 168, 464–477 (2015).
31. Zheng, Q. et al. Review of rhubarbs: Chemistry and pharmacology. Chinese Herb. Med. 5, 9–32 (2013).
32. Caro, Y. et al. Natural hydroxyanthraquinoid pigments as potent food grade colorants: an overview. Nat. Products Bioprospect. 2, 174–193 (2012).
33. Demirezer, L. O., Kuruüzüm-Uz, A., Bergere, I., Schiewe, H. J. & Zeeck, A. The structures of antioxidant and cytotoxic agents from natural source: anthraquinones and tannins from roots of Rumex patientia. Phytochemistry 58, 1213–7 (2001).
34. Yonekura-sakakibara, K., Fukushima, A. & Saito, K. Transcriptome data modeling for targeted plant metabolic engineering. Curr. Opin. Biotechnol. 24, 285–290 (2013).
35. Hirotani, M., Kuroda, R., Suzuki, H. & Yoshikawa, T. Cloning and expression of UDP-glucose: Flavonoid 7-O-glucosyltransferase from hairy root cultures of Scutellaria baicalensis. Planta 210, 1006 (2000).
36. Funaki, A. et al. Identification of a highly specific isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.). Plant Cell Physiol. 56, 1512–1520 (2015).
37. Nagatoshi, M., Terasaka, K., Nagatsu, A. & Mizukami, H. Iridoid-specific glucosyltransferase from Gardenia jasminoides. J. Biol. Chem. 286, 32866–32874 (2011).
38. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248–254 (1976).