MRI評価に基づく機械的血栓除去術後の頭蓋内高吸収領域に対するDECTの診断制度の検証

概要

Mechanical thrombectomy (MT) is an effective neuroendovascular treatment for acute
cerebral infarction caused by large cerebral vessel occlusion. However, hemorrhagic complications
such as subarachnoid hemorrhage and intraparenchymal hemorrhage will occur at a certain rate.
On the other hand, extravascular leakage of the contrast medium is observed after MT due to the
disruption of the local blood-brain barrier from acute cerebral ischemia. Since both conditions are
depicted as similar high density area in subarachnoid spaces or brain parenchyma on conventional
single-energy CT (SECT) scans. It has been difficult to distinguish hemorrhagic complications
from contrast agent leakage. Dual-energy CT (DECT) has two different X-ray energies to image
the target and obtains different X-ray absorption values from the same object. Thereby, DECT can
provide a high discrimination ability with respect to the object being imaged and is expected to
have clinical utility in differentiating blood, contrast media, and calcification. Recent reports
described DECT may be useful to distinguish the hemorrhagic complications from contrast
leakage after endovascular treatment. There are few reports to compare the diagnostic accuracy of
DECT with MRI. The purpose of our study was to validate the diagnostic accuracy of DECT for
hemorrhagic complications and leakage of contrast after MT by MRI. ...