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Long-Term Outcome of Sciatic Nerve Regeneration Using Bio3D Conduit Fabricated from Human Fibroblasts in a Rat Sciatic Nerve Model

Ando, Maki 京都大学 DOI:10.14989/doctor.k24481

2023.03.23

概要

Peripheral nerve regeneration for long nerve defects is the
most challenging aspect of the treatment of peripheral nerve
injury, and numerous studies employing various approaches
have been undertaken1–4. At present, the gold standard for
the treatment of peripheral nerve injuries with defects is
autologous nerve transplantation, but there are problems
related to the comorbidities of donor sites, including numbness and pain at the harvested site, mismatch in the diameter
between the recipient and the donor nerve, and the limitations in the length and number of nerves that can be
harvested5–8. ...

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参考文献

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