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大学・研究所にある論文を検索できる 「Relationship of Chronic Endometritis With Chronic Deciduitis in Cases of Miscarriage.」の論文概要。リケラボ論文検索は、全国の大学リポジトリにある学位論文・教授論文を一括検索できる論文検索サービスです。

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Relationship of Chronic Endometritis With Chronic Deciduitis in Cases of Miscarriage.

KAKU Shoji 50464178 KUBO Takuro KIMURA Fuminori 90322148 0000-0002-9840-4227 NAKAMURA Akiko 70839430 KITAZAWA Jun 30823900 MORIMUNE Aina 60757219 TAKAHASHI Akimasa 50452248 0000-0001-5698-553X TAKEBAYASHI Akie 00402735 0000-0001-6426-9082 TAKASHIMA Akiko 20452245 KUSHIMA Ryoji 40252382 MURAKAMI Takashi 20240666 0000-0002-0250-0856 滋賀医科大学

2020.06.01

概要

Background:
The presence of chronic deciduitis (CD) was determined in patients diagnosed with or without chronic endometritis (CE) before pregnancy.
Objective:
To study the effect of CE on decidua in cases of miscarriage.
Methods:
Decidual tissue was obtained from the patients who miscarried at the first pregnancy within a year after the diagnosis of the presence or absence of CE. The number and distribution pattern of plasma cells stained with CD138 in decidual tissue in 10 high-power fields (HPFs) was examined. The prevalence of CD diagnosed with four different grade; grade 0, no plasma cell in 10 HPFs, thus Non-CD;grade 1, rare single plasma cells; grade 2, rare clusters or more than 5 single cells total; and grade 3, many plasma cells with more than 5 clusters, were examined and compared between Non-CE and CE.
Results:
The incidence rate of CD of grade2 + 3 was significantly higher in CE than Non-CE (53.8%; 7/13 vs. 0%; 0/13, P < 0.01). Presence of clusters or a number of plasma cells in 10 HPFs of decidua showed a sensitivity of 53.8%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 68.4% for the diagnosis of CE.
Conclusion:
Presence of clusters of plasma cells or five or more of plasma cells in decidua was found in more than half of CE, but not found in Non-CE. When CD with cluster or five or more of plasma cells is confirmed histologically in miscarriage decidual tissue, the presence of CE before the pregnancy should be suspected.

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