Andersson LS, Larhammar M, Memic F, Wootz H, Schwochow D, Rubin CJ, Patra K, Arnason T, Wellbring L, Hjälm G, Imsland F, Petersen JL, McCue ME, Mickelson JR, Cothran G, Ahituv N, Roepstorff L, Mikko S, Vallstedt A, Lindgren G, et al. (2012) Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice. Nature 488:642– 646.
Arber S (2012) Motor circuits in action: specification, connectivity, and function. Neuron 74:975–989. Asakawa K, Suster ML, Mizusawa K, Nagayoshi S, Kotani T, Urasaki A, Kishimoto Y, Hibi M, Kawakami K (2008) Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish. Proc Natl Acad Sci U S A 105:1255–1260.
Britz O, Zhang J, Grossmann KS, Dyck J, Kim JC, Dymecki S, Gosgnach S, Goulding M. A genetically defined asymmetry underlies the inhibitory control of flexor-extensor locomotor movements. Elife. 2015 Oct 14;4:e04718. doi: 10.7554/eLife.04718. Erratum in: Elife. 2015;4:e13038.
Brown TG (1911) The intrinsic factors in the act of progression in the mammal. Proc Royal Acad Sci 84:308–319. Cazalets JR, Borde M, Clarac F (1996) The synaptic drive from the spinal locomotor network to motoneurons in the newborn rat. J Neurosci 16:298– 306.
Del Pozo A, Manuel R, Iglesias Gonzalez AB, Koning HK, Habicher J, Zhang H, Allalou A, Kullander K, Boije H (2020) Behavioral characterization of dmrt3a mutant zebrafish reveals crucial aspects of vertebrate locomotion through phenotypes related to acceleration. eNeuro 7:ENEURO.0047- 20.2020.
Delvolvé I, Bem T, Cabelguen JM. Epaxial and limb muscle activity during swimming and terrestrial stepping in the adult newt, Pleurodeles waltl. J Neurophysiol. 1997 Aug;78(2):638-50.
Ehrlich DE, Schoppik D (2019) A primal role for the vestibular sense in the development of coordinated locomotion. eLife 8:e45839. Endo T, Kiehn O (2008) Asymmetric operation of the locomotor central pattern generator in the neonatal mouse spinal cord. J Neurophysiol 100:3043–3054.
Goulding M (2009) Circuits controlling vertebrate locomotion: moving in a new direction. Nat Rev Neurosci 10:507–518.
Goulding M, Pfaff SL (2005) Development of circuits that generate simple rhythmic behaviors in vertebrates. Curr Opin Neurobiol 15:14–20.
Green MH, Hale ME (2012) Activity of pectoral fin motoneurons during two swimming gaits in the larval zebrafish (Danio rerio) and localization of upstream circuit elements. J Neurophysiol 108:3393–3402.
Green MH, Ho RK, Hale ME (2011) Movement and function of the pectoral fins of the larval zebrafish (Danio rerio) during slow swimming. J Exp Biol 214:3111–3123.
Grillner S (1975) Locomotion in vertebrates: central mechanisms and reflex interaction. Physiol Rev 55:247–304.
Grillner S (2003) The motor infrastructure: from ion channels to neuronal networks. Nat Rev Neurosci 4:573–586.
Hale ME, Day RD, Thorsen DH, Westneat MW (2006) Pectoral fin coordination and gait transitions in steadily swimming juvenile reef fishes. J Exp Biol 209:3708–3718.
Higashijima S, Masino MA, Mandel G, Fetcho JR. Engrailed-1 expression marks a primitive class of inhibitory spinal interneuron. J Neurosci. 2004 Jun 23;24(25):5827-39.
Hochman S, Schmidt BJ (1998) Whole cell recordings of lumbar motoneurons during locomotor-like activity in the in vitro neonatal rat spinal cord. J Neurophysiol 79:743–752.
Johnson MD, Hyngstrom AS, Manuel M, Heckman CJ (2012) Push-pull control of motor output. J Neurosci 32:4592–4599. Uemura et al. · Neuronal Circuits for Rhythmic Fin Movements J. Neurosci., August 26, 2020 • 40(35):6678–6690 • 6689
Juárez-Morales JL, Schulte CJ, Pezoa SA, Vallejo GK, Hilinski WC, England SJ, de Jager S, Lewis KE. Evx1 and Evx2 specify excitatory neurotransmitter fates and suppress inhibitory fates through a Pax2-independent mechanism. Neural Dev. 2016 Feb 19;11:5
Jung H, Baek M, D’Elia KP, Boisvert C, Currie PD, Tay B-H, Venkatesh B, Brown SM, Heguy A, Schoppik D, Dasen JS (2018) The ancient origins of neural substrates for land walking. Cell 172:667–682.e15.
Kiehn O (2006) Locomotor circuits in the mammalian spinal cord. Annu Rev Neurosci 29:279–306.
Kiehn O (2016) Decoding the organization of spinal circuits that control locomotion. Nat Rev Neurosci 17:224–238.
Kimura Y, Higashijima S-i (2019) Regulation of locomotor speed and selection of active sets of neurons by V1 neurons. Nat Commun 10:2268.
Kimura Y, Satou C, Fujioka S, Shoji W, Umeda K, Ishizuka T, Yawo H, Higashijima SI (2013) Hindbrain V2a neurons in the excitation of spinal locomotor circuits during zebrafish swimming. Curr Biol 23:843–849.
Kimura Y, Hisano Y, Kawahara A, Higashijima S-i (2014) Efficient generation of knock-in transgenic zebrafish carrying reporter/driver genes by CRISPR/Cas9-mediated genome engineering. Sci Rep 4:6545.
Kimura Y, Okamura Y, Higashijima S. alx, a zebrafish homolog of Chx10, marks ipsilateral descending excitatory interneurons that participate in the regulation of spinal locomotor circuits. J Neurosci. 2006 May 24;26(21):5684-97. doi: 10.1523/JNEUROSCI.4993- 05.2006.
Kjaerulff O, Kiehn O (1996) Distribution of networks generating and coordinating locomotor activity in the neonatal rat spinal cord in vitro: a lesion study. J Neurosci 16:5777–5794.
Lai HC, Seal RP, Johnson JE. Making sense out of spinal cord somatosensory development. Development. 2016 Oct 1;143(19):3434-3448.
Lundfald L, Restrepo CE, Butt SJ, Peng CY, Droho S, Endo T, Zeilhofer HU, Sharma K, Kiehn O. Phenotype of V2-derived interneurons and their relationship to the axon guidance molecule EphA4 in the developing mouse spinal cord. Eur J Neurosci. 2007 Dec;26(11):2989-3002.
Markin SN, Lemay MA, Prilutsky BI, Rybak IA. Motoneuronal and muscle synergies involved in cat hindlimb control during fictive and real locomotion: a comparison study. J
Neurophysiol. 2012 Apr;107(8):2057-71. Menelaou E, McLean DL (2019) Hierarchical control of locomotion by distinct types of spinal V2a interneurons in zebrafish. Nat Commun 10:4197.
Moran-Rivard L, Kagawa T, Saueressig H, Gross MK, Burrill J, Goulding M. Evx1 is a postmitotic determinant of v0 interneuron identity in the spinal cord. Neuron. 2001 Feb;29(2):385-99.
Natsubori A, Tsutsui-Kimura I, Nishida H, Bouchekioua Y, Sekiya H, Uchigashima M, Watanabe M, de Kerchove d’Exaerde A, Mimura M, Takata N, Tanaka KF (2017) Ventrolateral striatal medium spiny neurons positively regulate food-incentive, goaldirected behavior independently of D1 and D2 selectivity. J Neurosci 37:2723–2733.
Perry S, Larhammar M, Vieillard J, Nagaraja C, Hilscher MM, Tafreshiha A, Rofo F, Caixeta FV, Kullander K (2019) Characterization of Dmrt3- derived neurons suggest a role within locomotor circuits. J Neurosci 39:1771–1782.
Robertson GA, Stein PS (1988) Synaptic control of hindlimb motoneurones during three forms of the fictive scratch reflex in the turtle. J Physiol 404:101–128.
Rossignol S, Dubuc R, Gossard JP. Dynamic sensorimotor interactions in locomotion. Physiol Rev. 2006 Jan;86(1):89-154.
Satou C, Kimura Y, Kohashi T, Horikawa K, Takeda H, Oda Y, Higashijima S (2009) Functional role of a specialized class of spinal commissural inhibitory neurons during fast escapes in zebrafish. J Neurosci 29:6780– 6793.
Satou C, Kimura Y, Higashijima S (2012) Generation of multiple classes of V0 neurons in zebrafish spinal cord: progenitor heterogeneity and temporal control of neuronal diversity. J Neurosci 32:1771–1783.
Satou C, Kimura Y, Hirata H, Suster ML, Kawakami K, Higashijima S (2013) Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons. Development 140:3927–3931.
Satou C, Sugioka T, Uemura Y, Shimazaki T, Zmarz P, Kimura Y, Higashijima SI (2020) Functional diversity of glycinergic commissural inhibitory neurons in larval zebrafish. Cell Rep 30:3036–3050.e4.
Saueressig H, Burrill J, Goulding M. Engrailed-1 and netrin-1 regulate axon pathfinding by association interneurons that project to motor neurons. Development. 1999 Oct;126(19):4201-12.
Shefchyk SJ, Jordan LM (1985) Excitatory and inhibitory postsynaptic potentials in alphamotoneurons produced during fictive locomotion by stimulation of the mesencephalic locomotor region. J Neurophysiol 53:1345– 1355.
Stein PS (2010) Alternation of agonists and antagonists during turtle hindlimb motor rhythms. Ann N Y Acad Sci 1198:105–118.
Stein PS, Victor JC, Field EC, Currie SN (1995) Bilateral control of hindlimb scratching in the spinal turtle: contralateral spinal circuitry contributes to the normal ipsilateral motor pattern of fictive rostral scratching. J Neurosci 15:4343–4355.
Talpalar AE, Bouvier J, Borgius L, Fortin G, Pierani A, Kiehn O. Dual-mode operation of neuronal networks involved in left-right alternation. Nature. 2013 Aug 1;500(7460):85-8.
Taniguchi A, Kimura Y, Mori I, Nonaka S, Higashijima SI (2017) Axiallyconfined in vivo singlecell labeling by primed conversion using blue and red lasers with conventional confocal microscopes. Dev Growth Differ 59:741–748.
Thorsen DH, Hale ME (2005) Development of zebrafish (Danio rerio) pectoral fin musculature. J Morphol 266:241–255.
Thorsen DH, Hale ME (2007) Neural development of the zebrafish (Danio rerio) pectoral fin. J Comp Neurol 504:168–184. Thorsen DH, Cassidy JJ, Hale ME (2004) Swimming of larval zebrafish: finaxis coordination and implications for function and neural control. J Exp Biol 207:4175–4183.
Uemura O, Okada Y, Ando H, Guedj M, Higashijima S, Shimazaki T, Chino N, Okano H, Okamoto H (2005) Comparative functional genomics revealed conservation and diversification of three enhancers of the isl1 gene for motor and sensory neuron-specific expression. Dev Biol 278:587–606.
Urasaki A, Morvan G, Kawakami K (2006) Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition. Genetics 174:639–649.
Vallstedt A, Kullander K (2013) Dorsally derived spinal interneurons in locomotor circuits. Ann N Y Acad Sci 1279:32–42.
Vogel A, Rodriguez C, Warnken W, Izpisua Belmonte JC (1995) Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378:716-720
Wang H, Sugiyama Y, Hikima T, Sugano E, Tomita H, Takahashi T, Ishizuka T, Yawo H (2009) Molecular determinants differentiating photocurrent properties of two channelrhodopsins from chlamydomonas. J Biol Chem 284:5685–5696.