Acosta-Alvear D., Zhou Y., Blais A., Tsikitis M., Lents N. H., Arias C.,
Lennon C. J., Kluger Y. and Dynlacht B. D. (2007) XBP1 controls
diverse cell type- and condition-specific transcriptional regulatory
networks. Mol. Cell 27, 53–66.
Asada R., Kanemoto S., Matsuhisa K., Hino K., Cui M., Cui X., Kaneko
M. and Imaizumi K. (2015) IRE1alpha-XBP1 is a novel branch in
the transcriptional regulation of Ucp1 in brown adipocytes. Sci.
Rep. 5, 16580.
Barde Y. A., Edgar D. and Thoenen H. (1982) Purification of a new
neurotrophic factor from mammalian brain. EMBO J. 1, 549–
553.
Binder D. K. and Scharfman H. E. (2004) Brain-derived neurotrophic
factor. Growth Factors 22, 123–131.
Bolsover S. R. (2005) Calcium signalling in growth cone migration. Cell
Calcium 37, 395–402.
Broadwell R. D. and Cataldo A. M. (1983) The neuronal endoplasmic
reticulum: its cytochemistry and contribution to the endomembrane
system. I. Cell bodies and dendrites. J. Histochem. Cytochem. 31,
1077–1088.
Calfon M., Zeng H., Urano F., Till J. H., Hubbard S. R., Harding H. P.,
Clark S. G. and Ron D. (2002) IRE1 couples endoplasmic
reticulum load to secretory capacity by processing the XBP-1
mRNA. Nature 415, 92–96.
Chen G., Kolbeck R., Barde Y. A., Bonhoeffer T. and Kossel A. (1999)
Relative contribution of endogenous neurotrophins in hippocampal
long-term potentiation. J. Neurosci. 19, 7983–7990.
Citri A. and Malenka R. C. (2008) Synaptic plasticity: multiple forms,
functions, and mechanisms. Neuropsychopharmacology 33, 18–41.
© 2017 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of
International Society for Neurochemistry, J. Neurochem. (2018) 144, 35--49
48
A. Saito et al.
Davies S. P., Reddy H., Caivano M. and Cohen P. (2000) Specificity and
mechanism of action of some commonly used protein kinase
inhibitors. Biochem. J. 351, 95–105.
Delghandi M. P., Johannessen M. and Moens U. (2005) The cAMP
signalling pathway activates CREB through PKA, p38 and MSK1
in NIH 3T3 cells. Cell. Signal. 17, 1343–1351.
Gulledge A. T., Kampa B. M. and Stuart G. J. (2005) Synaptic
integration in dendritic trees. J. Neurobiol. 64, 75–90.
Harding H. P., Zhang Y. and Ron D. (1999) Protein translation and
folding are coupled by an endoplasmic-reticulum-resident kinase.
Nature 397, 271–274.
Harding H. P., Novoa I., Zhang Y., Zeng H., Wek R., Schapira M. and Ron
D. (2000) Regulated translation initiation controls stress-induced
gene expression in mammalian cells. Mol. Cell 6, 1099–1108.
Hayashi A., Kasahara T., Iwamoto K., Ishiwata M., Kametani M.,
Kakiuchi C., Furuichi T. and Kato T. (2007) The role of brainderived neurotrophic factor (BDNF)-induced XBP1 splicing during
brain development. J. Biol. Chem. 282, 34525–34534.
Hayashi A., Kasahara T., Kametani M. and Kato T. (2008) Attenuated
BDNF-induced upregulation of GABAergic markers in neurons
lacking Xbp1. Biochem. Biophys. Res. Comm. 376, 758–763.
Headley P. M. and Grillner S. (1990) Excitatory amino acids and
synaptic transmission: the evidence for a physiological function.
Trends Pharmacol. Sci. 11, 205–211.
Hetz C., Thielen P., Matus S. et al. (2009) XBP-1 deficiency in the
nervous system protects against amyotrophic lateral sclerosis by
increasing autophagy. Genes Dev. 23, 2294–2306.
Hu Y., Park K. K., Yang L. et al. (2012) Differential effects of unfolded
protein response pathways on axon injury-induced death of retinal
ganglion cells. Neuron 73, 445–452.
Iida J., Ishizaki H., Okamoto-Tanaka M. et al. (2007) Synaptic
scaffolding molecule alpha is a scaffold to mediate N-methyl-Daspartate receptor-dependent RhoA activation in dendrites. Mol.
Cell. Biol. 27, 4388–4405.
Kakiuchi C., Iwamoto K., Ishiwata M. et al. (2003) Impaired feedback
regulation of XBP1 as a genetic risk factor for bipolar disorder.
Nat. Genet. 35, 171–175.
Kakiuchi C., Ishiwata M., Umekage T., Tochigi M., Kohda K., Sasaki T.
and Kato T. (2004) Association of the XBP1-116C/G
polymorphism with schizophrenia in the Japanese population.
Psychiatry Clin. Neurosci. 58, 438–440.
Kaufman R. J. (2002) Orchestrating the unfolded protein response in
health and disease. J. Clin. Investig. 110, 1389–1398.
Kitao Y., Ozawa K., Miyazaki M. et al. (2001) Expression of the
endoplasmic reticulum molecular chaperone (ORP150) rescues
hippocampal neurons from glutamate toxicity. J. Clin. Investig.
108, 1439–1450.
Kondo S., Murakami T., Tatsumi K., Ogata M., Kanemoto S., Otori K.,
Iseki K., Wanaka A. and Imaizumi K. (2005) OASIS, a CREB/
ATF-family member, modulates UPR signalling in astrocytes. Nat.
Cell Biol. 7, 186–194.
Korte M., Carroll P., Wolf E., Brem G., Thoenen H. and Bonhoeffer T.
(1995) Hippocampal long-term potentiation is impaired in mice
lacking brain-derived neurotrophic factor. Proc. Natl Acad. Sci.
USA 92, 8856–8860.
Koscielny A., Malik A. R., Liszewska E., Zmorzynska J., Tempes A.,
Tarkowski B. and Jaworski J. (2017) Adaptor complex 2 controls
dendrite morphology via mTOR-dependent expression of GluA2.
Mol. Neurobiol. doi: 10.1007/s12035-017-0436-3.
Lee J., Sun C., Zhou Y., Lee J., Gokalp D., Herrema H., Park S. W., Davis
R. J. and Ozcan U. (2011) p38 MAPK-mediated regulation of
Xbp1s is crucial for glucose homeostasis. Nat. Med. 17, 1251–1260.
Leibrock J., Lottspeich F., Hohn A., Hofer M., Hengerer B.,
Masiakowski P., Thoenen H. and Barde Y. A. (1989) Molecular
cloning and expression of brain-derived neurotrophic actor. Nature
341, 149–152.
Lessmann V., Gottmann K. and Heumann R. (1994) BDNF and NT-4/5
enhance glutamatergic synaptic transmission in cultured
hippocampal neurones. NeuroReport 6, 21–25.
Li M., Baumeister P., Roy B., Phan T., Foti D., Luo S. and Lee A. S.
(2000) ATF6 as a transcription activator of the endoplasmic
reticulum stress element: thapsigargin stress-induced changes and
synergistic interactions with NF-Y and YY1. Mol. Cell. Biol. 20,
5096–5106.
Lin G., Bella A. J., Lue T. F. and Lin C. S. (2006) Brain-derived
neurotrophic factor (BDNF) acts primarily via the JAK/STAT
pathway to promote neurite growth in the major pelvic ganglion of
the rat: part 2. J. Sex. Med. 3, 821–827; discussion 828–829.
Liu S. Y., Wang W., Cai Z. Y., Yao L. F., Chen Z. W., Wang C. Y.,
Zhao B. and Li K. S. (2013) Polymorphism -116C/G of human Xbox-binding protein 1 promoter is associated with risk of
Alzheimer’s disease. CNS Neurosci. Ther. 19, 229–234.
Lohof A. M., Ip N. Y. and Poo M. M. (1993) Potentiation of developing
neuromuscular synapses by the neurotrophins NT-3 and BDNF.
Nature 363, 350–353.
Lommatzsch M., Braun A., Mannsfeldt A., Botchkarev V. A.,
Botchkareva N. V., Paus R., Fischer A., Lewin G. R. and Renz
H. (1999) Abundant production of brain-derived neurotrophic
factor by adult visceral epithelia. Implications for paracrine and
target-derived Neurotrophic functions. Am. J. Pathol. 155, 1183–
1193.
Lu H., Park H. and Poo M. M. (2014) Spike-timing-dependent BDNF
secretion and synaptic plasticity. Philos. Trans. R. Soc. Lond. B
Biol. Sci. 369, 20130132.
Madeo F., Eisenberg T. and Kroemer G. (2009) Autophagy for the
avoidance of neurodegeneration. Genes Dev. 23, 2253–2259.
Malenka R. C. and Bear M. F. (2004) LTP and LTD: an embarrassment
of riches. Neuron 44, 5–21.
Malik A. R., Urbanska M., Gozdz A., Swiech L. J., Nagalski A., Perycz
M., Blazejczyk M. and Jaworski J. (2013) Cyr61, a matricellular
protein, is needed for dendritic arborization of hippocampal
neurons. J. Biol. Chem. 288, 8544–8559.
Mao T., Shao M., Qiu Y. et al. (2011) PKA phosphorylation couples
hepatic inositol-requiring enzyme 1alpha to glucagon signaling in
glucose metabolism. Proc. Natl Acad. Sci. USA 108, 15852–15857.
Martinez G., Vidal R. L., Mardones P. et al. (2016) Regulation of
Memory Formation by the Transcription Factor XBP1. Cell Rep.
14, 1382–1394.
Mazer C., Muneyyirci J., Taheny K., Raio N., Borella A. and WhitakerAzmitia P. (1997) Serotonin depletion during synaptogenesis leads
to decreased synaptic density and learning deficits in the adult rat: a
possible model of neurodevelopmental disorders with cognitive
deficits. Brain Res. 760, 68–73.
Minichiello L. (2009) TrkB signalling pathways in LTP and learning.
Nat. Rev. Neurosci. 10, 850–860.
Miyamoto Y., Yamauchi J., Tanoue A., Wu C. and Mobley W. C. (2006)
TrkB binds and tyrosine-phosphorylates Tiam1, leading to
activation of Rac1 and induction of changes in cellular
morphology. Proc. Natl Acad. Sci. USA 103, 10444–10449.
Murakami T., Hino S. I., Saito A. and Imaizumi K. (2007) Endoplasmic
reticulum stress response in dendrites of cultured primary neurons.
Neuroscience 146, 1–8.
Negro A., Tavella A., Grandi C. and Skaper S. D. (1994) Production and
characterization of recombinant rat brain-derived neurotrophic
factor and neurotrophin-3 from insect cells. J. Neurochem. 62,
471–478.
Ng D. T., Spear E. D. and Walter P. (2000) The unfolded protein
response regulates multiple aspects of secretory and membrane
© 2017 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of
International Society for Neurochemistry, J. Neurochem. (2018) 144, 35--49
Dendritic IRE1 handles neurofunction via BDNF
protein biogenesis and endoplasmic reticulum quality control.
J. Cell Biol. 150, 77–88.
Nicholls D. and Attwell D. (1990) The release and uptake of excitatory
amino acids. Trends Pharmacol. Sci. 11, 462–468.
Nicoll R. A. and Schmitz D. (2005) Synaptic plasticity at hippocampal
mossy fibre synapses. Nat. Rev. Neurosci. 6, 863–876.
Ogura A., Miyamoto M. and Kudo Y. (1988) Neuronal death in vitro:
parallelism between survivability of hippocampal neurones and
sustained elevation of cytosolic Ca2 + after exposure to glutamate
receptor agonist. Exp. Brain Res. 73, 447–458.
Okubo Y., Suzuki J., Kanemaru K., Nakamura N., Shibata T. and Iino
M. (2015) Visualization of Ca2 + Filling Mechanisms upon
Synaptic Inputs in the Endoplasmic Reticulum of Cerebellar
Purkinje Cells. J. Neurosci. 35, 15837–15846.
Olson M. F. (2004) Contraction reaction: mechanical regulation of Rho
GTPase. Trends Cell Biol. 14, 111–114.
Park H. and Poo M. M. (2013) Neurotrophin regulation of neural circuit
development and function. Nat. Rev. Neurosci. 14, 7–23.
Ron D. (2002) Translational control in the endoplasmic reticulum stress
response. J. Clin. Investig. 110, 1383–1388.
Ron D. and Walter P. (2007) Signal integration in the endoplasmic
reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8,
519–529.
Rutkowski D. T. and Kaufman R. J. (2004) A trip to the ER: coping with
stress. Trends Cell Biol. 14, 20–28.
Sandhya V. K., Raju R., Verma R. et al. (2013) A network map of
BDNF/TRKB and BDNF/p75NTR signaling system. J. Cell
Commun. Signal. 7, 301–307.
Saneyoshi T., Fortin D. A. and Soderling T. R. (2010) Regulation of
spine and synapse formation by activity-dependent intracellular
signaling pathways. Curr. Opin. Neurobiol. 20, 108–115.
Sfakianos M. K., Eisman A., Gourley S. L. et al. (2007) Inhibition of
Rho via Arg and p190RhoGAP in the postnatal mouse
hippocampus regulates dendritic spine maturation, synapse and
dendrite stability, and behavior. J. Neurosci. 27, 10982–10992.
Shah S. Z., Zhao D., Khan S. H. and Yang L. (2015) Unfolded protein
response pathways in neurodegenerative diseases. J. Mol.
Neurosci. 57, 529–537.
Spruston N. (2008) Pyramidal neurons: dendritic structure and synaptic
integration. Nat. Rev. Neurosci. 9, 206–221.
Thakker-Varia S., Alder J., Crozier R. A., Plummer M. R. and Black I.
B. (2001) Rab3A is required for brain-derived neurotrophic factorinduced synaptic plasticity: transcriptional analysis at the
population and single-cell levels. J. Neurosci. 21, 6782–6790.
Tirasophon W., Welihinda A. A. and Kaufman R. J. (1998) A stress
response pathway from the endoplasmic reticulum to the nucleus
requires a novel bifunctional protein kinase/endoribonuclease
(Ire1p) in mammalian cells. Genes Dev. 12, 1812–1824.
Travers K. J., Patil C. K., Wodicka L., Lockhart D. J., Weissman J. S.
and Walter P. (2000) Functional and genomic analyses reveal an
essential coordination between the unfolded protein response and
ER-associated degradation. Cell 101, 249–258.
Trinh M. A., Ma T., Kaphzan H., Bhattacharya A., Antion M. D.,
Cavener D. R., Hoeffer C. A. and Klann E. (2014) The eIF2alpha
kinase PERK limits the expression of hippocampal metabotropic
49
glutamate receptor-dependent long-term depression. Learn. Mem.
21, 298–304.
Tsukita S. and Ishikawa H. (1976) Three-dimensional distribution of
smooth endoplasmic reticulum in myelinated axons. J. Electron
Microsc. 25, 141–149.
Urban P., Pavlikova M., Sivonova M., Kaplan P., Tatarkova Z.,
Kaminska B. and Lehotsky J. (2009) Molecular analysis of
endoplasmic reticulum stress response after global forebrain
ischemia/reperfusion in rats: effect of neuroprotectant
simvastatin. Cell. Mol. Neurobiol. 29, 181–192.
Valenzuela V., Collyer E., Armentano D., Parsons G. B., Court F. A. and
Hetz C. (2012) Activation of the unfolded protein response
enhances motor recovery after spinal cord injury. Cell Death Dis.
3, e272.
Wang X. Z., Harding H. P., Zhang Y., Jolicoeur E. M., Kuroda M. and
Ron D. (1998) Cloning of mammalian Ire1 reveals diversity in the
ER stress responses. EMBO J. 17, 5708–5717.
Wei X., Howell A. S., Dong X., Taylor C. A., Cooper R. C., Zhang J.,
Zou W., Sherwood D. R. and Shen K. (2015) The unfolded protein
response is required for dendrite morphogenesis. eLife 4, e06963.
Wetmore C., Olson L. and Bean A. J. (1994) Regulation of brain-derived
neurotrophic factor (BDNF) expression and release from
hippocampal neurons is mediated by non-NMDA type glutamate
receptors. J. Neurosci. 14, 1688–1700.
Yoshida H., Haze K., Yanagi H., Yura T. and Mori K. (1998)
Identification of the cis-acting endoplasmic reticulum stress
response element responsible for transcriptional induction of
mammalian glucose-regulated proteins. Involvement of basic
leucine zipper transcription factors. J. Biol. Chem. 273, 33741–
33749.
Yoshida H., Okada T., Haze K., Yanagi H., Yura T., Negishi M. and
Mori K. (2000) ATF6 activated by proteolysis binds in the
presence of NF-Y (CBF) directly to the cis-acting element
responsible for the mammalian unfolded protein response. Mol.
Cell. Biol. 20, 6755–6767.
Yoshida H., Matsui T., Yamamoto A., Okada T. and Mori K. (2001)
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response
to ER stress to produce a highly active transcription factor. Cell
107, 881–891.
Yoshida H., Matsui T., Hosokawa N., Kaufman R. J., Nagata K. and
Mori K. (2003) A time-dependent phase shift in the mammalian
unfolded protein response. Dev. Cell 4, 265–271.
Yu Z., Luo H., Fu W. and Mattson M. P. (1999) The endoplasmic
reticulum stress-responsive protein GRP78 protects neurons
against excitotoxicity and apoptosis: suppression of oxidative
stress and stabilization of calcium homeostasis. Exp. Neurol. 155,
302–314.
Zachor D. A., Moore J. F., Brezausek C., Theibert A. and Percy A. K.
(2000) Cocaine inhibits NGF-induced PC12 cells differentiation
through D(1)-type dopamine receptors. Brain Res. 869, 85–97.
Zafra F., Castren E., Thoenen H. and Lindholm D. (1991) Interplay
between glutamate and gamma-aminobutyric acid transmitter
systems in the physiological regulation of brain-derived
neurotrophic factor and nerve growth factor synthesis in
hippocampal neurons. Proc. Natl Acad. Sci. USA 88, 10037–10041.
© 2017 The Authors. Journal of Neurochemistry published by John Wiley & Sons Ltd on behalf of
International Society for Neurochemistry, J. Neurochem. (2018) 144, 35--49
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