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Acknowledgements
We thank Dr. Yoshihiko Fujita (Kyoto University), Dr. Tatsuyuki Yoshii
(Kyoto University), Dr. Shin Kaneko (Kyoto University), Dr. Atsutaka Minagawa (Kyoto University), and Dr. Yoshihiro Shimizu (RIKEN) for helpful
discussions, and Dr. Shunsuke Kawasaki (Kyoto University) and Dr. Moe
Hirosawa (Kyoto University) for supplying materials. Dr. Kanae Mitsunaga
(Kyoto University) for technical assistance, Dr. Kelvin K. Hui (Kyoto University) and Maya Lopez (Imperial College London) for proofreading the
manuscript, and Yuko Kono, Hiromi Takemoto, and Yoshiko Ogawa for
their administrative support, and Dr. Dan Liu (National Institute of
Technology, Ariake College) for encouragement throughout the
research process. S.K. was supported by Scholarships from Iwadare
Scholarship Foundation and Honjo International Scholarship Foundation. This work was supported by JST SPRING, Grant Number
JPMJSP2110. This work was also supported by the JSPS KAKENHI (Grant
Numbers JP20H05626 and 20H05701) and iPS Cell Research Fund from
Center for iPS Cell Research and Application, Kyoto University.
Nature Communications | (2023)14:7256
https://doi.org/10.1038/s41467-023-42802-5
Author contributions
S.K. performed all the experiments. S.K., H.O., and H.S. designed
experimental strategies and wrote the paper.
Competing interests
The authors declare no competing interests.
Additional information
Supplementary information The online version contains
supplementary material available at
https://doi.org/10.1038/s41467-023-42802-5.
Correspondence and requests for materials should be addressed to
Hirohide Saito.
Peer review information Nature Communications thanks Kirill Alexandrov, and the other, anonymous, reviewer(s) for their contribution to the
peer review of this work. A peer review file is available.
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