1.
Vincent JL, Ince C and Bakker J. Clinical review: Circulatory shock--an update: a tribute
to Professor Max Harry Weil. Critical care (London, England). 2012;16:239.
2.
Bellamy MC. Wet, dry or something else? British journal of anaesthesia. 2006;97:755-7.
3.
American College of S and Committee on T. ATLS : Advanced Trauma Life Support for
doctors : student course manual. Chicago, IL: American College of Surgeons; 2008.
4.
Rosen P. Rosens emergency medicine. 1 1. Philadelphia: Mosby Elsevier; 2010.
5.
Gattinoni L, Brazzi L, Pelosi P, Latini R, Tognoni G, Pesenti A and Fumagalli R. A trial
of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. The
New England journal of medicine. 1995;333:1025-32.
6.
Marik PE, Monnet X and Teboul JL. Hemodynamic parameters to guide fluid therapy.
Annals of intensive care. 2011;1:1.
7.
Cecconi M, Parsons AK and Rhodes A. What is a fluid challenge? Current opinion in
critical care. 2011;17:290-5.
8.
Marik PE. Obituary: pulmonary artery catheter 1970 to 2013. Annals of intensive care.
2013;3:38.
9.
Goedje O, Hoeke K, Lichtwarck-Aschoff M, Faltchauser A, Lamm P and Reichart B.
Continuous cardiac output by femoral arterial thermodilution calibrated pulse contour analysis:
49
comparison with pulmonary arterial thermodilution. Crit Care Med. 1999;27:2407-12.
10.
Reuter DA, Kirchner A, Felbinger TW, Weis FC, Kilger E, Lamm P and Goetz AE.
Usefulness of left ventricular stroke volume variation to assess fluid responsiveness in patients with
reduced cardiac function. Crit Care Med. 2003;31:1399-404.
11.
De Backer D, Heenen S, Piagnerelli M, Koch M and Vincent JL. Pulse pressure
variations to predict fluid responsiveness: influence of tidal volume. Intensive care medicine.
2005;31:517-23.
12.
Van De Water JM, Miller TW, Vogel RL, Mount BE and Dalton ML. Impedance
cardiography: the next vital sign technology? Chest. 2003;123:2028-33.
13.
Monnet X, Dres M, Ferre A, Le Teuff G, Jozwiak M, Bleibtreu A, Le Deley MC, Chemla
D, Richard C and Teboul JL. Prediction of fluid responsiveness by a continuous non-invasive
assessment of arterial pressure in critically ill patients: comparison with four other dynamic indices.
British journal of anaesthesia. 2012;109:330-8.
14.
Krishnamoorthy VK, Sengupta PP, Gentile F and Khandheria BK. History of
echocardiography and its future applications in medicine. Crit Care Med. 2007;35:S309-13.
15.
Moore CL and Copel JA. Point-of-care ultrasonography. The New England journal of
medicine. 2011;364:749-57.
16.
Boyd JH, Sirounis D, Maizel J and Slama M. Echocardiography as a guide for fluid
50
management. Critical care (London, England). 2016;20:274.
17.
Zhang Z, Xu X, Ye S and Xu L. Ultrasonographic measurement of the respiratory
variation in the inferior vena cava diameter is predictive of fluid responsiveness in critically ill
patients: systematic review and meta-analysis. Ultrasound in medicine & biology. 2014;40:845-53.
18.
Stawicki SP, Braslow BM, Panebianco NL, Kirkpatrick JN, Gracias VH, Hayden GE and
Dean AJ. Intensivist use of hand-carried ultrasonography to measure IVC collapsibility in
estimating intravascular volume status: correlations with CVP. Journal of the American College of
Surgeons. 2009;209:55-61.
19.
Long E, Oakley E, Duke T and Babl FE. Does Respiratory Variation in Inferior Vena
Cava Diameter Predict Fluid Responsiveness: A Systematic Review and Meta-Analysis. Shock
(Augusta, Ga). 2017;47:550-559.
20.
Via G, Tavazzi G and Price S. Ten situations where inferior vena cava ultrasound may
fail to accurately predict fluid responsiveness: a physiologically based point of view. Intensive care
medicine. 2016;42:1164-7.
21.
Lipton B. Estimation of central venous pressure by ultrasound of the internal jugular
vein. The American journal of emergency medicine. 2000;18:432-4.
22.
Donahue SP, Wood JP, Patel BM and Quinn JV. Correlation of sonographic
measurements of the internal jugular vein with central venous pressure. The American journal of
51
emergency medicine. 2009;27:851-5.
23.
Pestel GJ, Fukui K, Kimberger O, Hager H, Kurz A and Hiltebrand LB. Hemodynamic
parameters change earlier than tissue oxygen tension in hemorrhage. The Journal of surgical
research. 2010;160:288-93.
24.
Suess EM and Pinsky MR. Hemodynamic Monitoring for the Evaluation and Treatment
of Shock: What Is the Current State of the Art? Seminars in respiratory and critical care medicine.
2015;36:890-8.
25.
Feng Y, Zou Y, Zheng Y, Levin NW and Wang L. The value of non-invasive measurement
of cardiac output and total peripheral resistance to categorize significant changes of intradialytic
blood pressure: a prospective study. BMC nephrology. 2018;19:310.
26.
Unluer EE and Kara PH. Ultrasonography of jugular vein as a marker of hypovolemia in
healthy volunteers. The American journal of emergency medicine. 2013;31:173-7.
27.
Abel FL and Waldhausen JA. Respiratory and cardiac effects on venous return. American
heart journal. 1969;78:266-75.
28.
Nakamura K, Tomida M, Ando T, Sen K, Inokuchi R, Kobayashi E, Nakajima S, Sakuma
I and Yahagi N. Cardiac variation of inferior vena cava: new concept in the evaluation of
intravascular blood volume. Journal of medical ultrasonics (2001). 2013;40:205-9.
29.
Nakamura K, Qian K, Ando T, Inokuchi R, Doi K, Kobayashi E, Sakuma I, Nakajima S
52
and Yahagi N. Cardiac Variation of Internal Jugular Vein for the Evaluation of Hemodynamics.
Ultrasound in medicine & biology. 2016;42:1764-70.
30.
Hocking KM, Alvis BD, Baudenbacher F, Boyer R, Brophy CM, Beer I and Eagle S.
Peripheral i.v. analysis (PIVA) of venous waveforms for volume assessment in patients undergoing
haemodialysis. British journal of anaesthesia. 2017;119:1135-1140.
31.
Hocking KM, Sileshi B, Baudenbacher FJ, Boyer RB, Kohorst KL, Brophy CM and Eagle
SS. Peripheral Venous Waveform Analysis for Detecting Hemorrhage and Iatrogenic Volume
Overload in a Porcine Model. Shock (Augusta, Ga). 2016;46:447-52.
32.
Qian K, Ando T, Nakamura K, Liao H, Kobayashi E, Yahagi N and Sakuma I. Ultrasound
imaging method for internal jugular vein measurement and estimation of circulating blood volume.
International journal of computer assisted radiology and surgery. 2014;9:231-9.
33.
Lobo SM and de Oliveira NE. Clinical review: What are the best hemodynamic targets
for noncardiac surgical patients? Critical care (London, England). 2013;17:210.
34.
Monge García MI, Guijo González P, Gracia Romero M, Gil Cano A, Oscier C, Rhodes
A, Grounds RM and Cecconi M. Effects of fluid administration on arterial load in septic shock
patients. Intensive care medicine. 2015;41:1247-55.
35.
Feissel M, Michard F, Mangin I, Ruyer O, Faller JP and Teboul JL. Respiratory changes
in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic
53
shock. Chest. 2001;119:867-73.
36.
Nagdev AD, Merchant RC, Tirado-Gonzalez A, Sisson CA and Murphy MC. Emergency
department bedside ultrasonographic measurement of the caval index for noninvasive
determination of low central venous pressure. Ann Emerg Med. 2010;55:290-5.
37.
Corl K, Napoli AM and Gardiner F. Bedside sonographic measurement of the inferior
vena cava caval index is a poor predictor of fluid responsiveness in emergency department patients.
Emergency medicine Australasia : EMA. 2012;24:534-9.
38.
Sobczyk D, Nycz K, Andruszkiewicz P, Wierzbicki K and Stapor M. Ultrasonographic
caval indices do not significantly contribute to predicting fluid responsiveness immediately after
coronary artery bypass grafting when compared to passive leg raising. Cardiovascular ultrasound.
2016;14:23.
39.
Carsetti A, Cecconi M and Rhodes A. Fluid bolus therapy: monitoring and predicting
fluid responsiveness. Current opinion in critical care. 2015;21:388-94.
40.
Frank RC, Min J, Abdelghany M, Paniagua S, Bhattacharya R, Bhambhani V,
Pomerantsev E and Ho JE. Obesity Is Associated With Pulmonary Hypertension and Modifies
Outcomes. Journal of the American Heart Association. 2020;9:e014195.
41.
Lam CS, Borlaug BA, Kane GC, Enders FT, Rodeheffer RJ and Redfield MM. Age-
associated increases in pulmonary artery systolic pressure in the general population. Circulation.
54
2009;119:2663-70.
42.
Conn RD and O'Keefe JH. Simplified evaluation of the jugular venous pressure:
significance of inspiratory collapse of jugular veins. Missouri medicine. 2012;109:150-2.
43.
Guarracino F, Ferro B, Forfori F, Bertini PG, Magliacano L and Pinsky MR. Jugular vein
distensibility predicts fluid responsiveness in septic patients. Critical care (London, England).
2014;18:647.
44.
Akilli NB, Cander B, Dundar ZD and Koylu R. A new parameter for the diagnosis of
hemorrhagic shock: jugular index. Journal of critical care. 2012;27:530.e13-8.
45.
Fülöp A, Turóczi Z, Garbaisz D, Harsányi L and Szijártó A. Experimental models of
hemorrhagic shock: a review. European surgical research Europaische chirurgische Forschung
Recherches chirurgicales europeennes. 2013;50:57-70.
46.
Cherpanath TG, Hirsch A, Geerts BF, Lagrand WK, Leeflang MM, Schultz MJ and
Groeneveld AB. Predicting Fluid Responsiveness by Passive Leg Raising: A Systematic Review
and Meta-Analysis of 23 Clinical Trials. Crit Care Med. 2016;44:981-91.
47.
Saul T, Lewiss RE, Langsfeld A, Radeos MS and Del Rios M. Inter-rater reliability of
sonographic measurements of the inferior vena cava. The Journal of emergency medicine.
2012;42:600-5.
48.
Wang C, Li X, Hu H, Zhang L, Huang Z, Lin M, Zhang Z, Yin Z, Huang B, Gong H,
55
Bhaskaran S, Gu Y, Makihata M, Guo Y, Lei Y, Chen Y, Wang C, Li Y, Zhang T, Chen Z, Pisano
AP, Zhang L, Zhou Q and Xu S. Monitoring of the central blood pressure waveform via a conformal
ultrasonic device. Nature Biomedical Engineering. 2018;2:687-695.
49.
Prasetiyo RB, Choi KS and Yang GH. Design and Implementation of Respiration Rate
Measurement System Using an Information Filter on an Embedded Device. Sensors (Basel,
Switzerland). 2018;18.
50.
Alpert MA, Karthikeyan K, Abdullah O and Ghadban R. Obesity and Cardiac
Remodeling in Adults: Mechanisms and Clinical Implications. Progress in cardiovascular diseases.
2018;61:114-123.
51.
Wolsk E, Bakkestrom R, Thomsen JH, Balling L, Andersen MJ, Dahl JS, Hassager C,
Moller JE and Gustafsson F. The Influence of Age on Hemodynamic Parameters During Rest and
Exercise in Healthy Individuals. JACC Heart failure. 2017;5:337-346.
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謝辞
本研究は東京大学大学院医学系研究科救急科学において森村尚登教授、土井研
人准教授、中村謙介医師による指導の下に遂行されたものである。このような貴
重な研究の機会を与えてくださったこと、研究の構想、実施、論文の作成の過程
で懇切丁寧にご指導くださったことなど感謝に堪えない。共同研究者である医
学系研究科輸血医学の岡崎仁教授、池田敏之講師、寺田類先生には自己血患者の
貴重なデータ採取にご協力いただいた。また東京大学大学院工学系研究科精密
工学専攻医用精密工学の佐久間一郎教授、富岡悠二研究員、東京大学大学院工学
系研究科精密工学専攻治療支援工学の小林英津子教授、名古屋工業大学大学院
工学研究科情報工学専攻の本谷秀堅教授にソフトウェア開発においてご指導い
ただいた。医学系研究科リハビリテーション医学の遠藤聡医師にはデータ解析
手法にアドバイスをいただいた。この場を借りて感謝を申し上げたい。
57
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