Structural Energy Bioscience Research Section
概要
We explore the way how biomolecules such as pro- teins (involving enzymes) and functional nucleic acids (DNA and RNA) work at atomic resolution based on structural biology with NMR. We determine both static and dynamical structures with the aid of our own development of the new methodology and elucidate the underlying mechanism of functions of these bio- molecules. Structural biological approach is also ap- plied to analyze enzymes involved in degradation of wood biomass at atomic resolution. The analysis is useful to develop the way to extract energy and valua- ble materials that can be used as starting materials of various products from the wood biomass. Thus, we pursue to contribute to the paradigm shift from oil re- finery to biorefinery. Followings are main research achievements in the year of 2020.