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We thank Ms. Harumi Watanabe for providing administrative assistance, Dr.

Peter Karagiannis for proofreading the article, Dr. Misaki Ouchida for

graphical assistance, and Drs. Shiori Ando and Hideaki Hara for technical

support. This work was supported by grants from the Japan Society for the

Promotion of Science KAKENHI Grant Numbers 16H0552 (MK Saito) and

20H03642 (MK Saito), the Core Center for iPS Cell Research of Research

Center Network for Realization of Regenerative Medicine from Japan Agency

for Medical Research and Development JP21bm0104001 (T Nakahata and MK

Saito), and the iPS Cell Research Fund (MK Saito).

Author Contributions

A Ikenaka: conceptualization, data curation, investigation, visualization, and writing—original draft.

Y Kitagawa: data curation, investigation, visualization, methodology,

and writing—original draft.

M Yoshida: conceptualization, investigation, and writing—review

and editing.

C-Y Lin: investigation, visualization, and writing—review and editing.

A Niwa: data curation, supervision, and writing—review and editing.

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