1) Nakasu S, Hirano A, Shimura T, Llena JF: Incidental
meningiomas in autopsy study. Surg Neurol 27:
319–322, 1987
2) Rausing A, Ybo W, Stenflo J: Intracranial meningioma—a
population study of ten years. Acta Neurol Scand
46: 102–110, 1970
3) Bos D, Poels MM, Adams HH, et al.: Prevalence,
clinical management, and natural course of incidental
findings on brain MR images: the population-based
Rotterdam scan study. Radiology 281: 507–515,
2016
4) Behbahani M, Skeie GO, Eide GE, Hausken A,
Lund-Johansen M, Skeie BS: A prospective study
of the natural history of incidental meningioma—
Hold your horses! Neuro-Oncol Pract 6: 438–450,
2019
5) Firsching RP, Fischer A, Peters R, Thun F, Klug N:
Growth rate of incidental meningiomas. J Neurosurg
73: 545–547, 1990
6) Hashiba T, Hashimoto N, Izumoto S, et al.: Serial
volumetric assessment of the natural history and
growth pattern of incidentally discovered meningiomas. J Neurosurg 110: 675–684, 2009
7) Hashimoto N, Rabo CS, Okita Y, et al.: Slower growth
of skull base meningiomas compared with nonskull base meningiomas based on volumetric and
biological studies. J Neurosurg 116: 574–580, 2012
8) Jo KW, Kim CH, Kong DS, et al.: Treatment modalities and outcomes for asymptomatic meningiomas.
Acta Neurochir (Wien) 153: 62–67; discussion 67,
2011
9) Kim KH, Kang SJ, Choi JW, et al.: Clinical and radiological outcomes of proactive Gamma Knife surgery
for asymptomatic meningiomas compared with the
natural course without intervention. J Neurosurg
130: 1740–1749, 2018
10) Kuratsu J, Kochi M, Ushio Y: Incidence and clinical
features of asymptomatic meningiomas. J Neurosurg
92: 766–770, 2000
11) Nakasu S, Fukami T, Nakajima M, Watanabe K,
Ichikawa M, Matsuda M: Growth pattern changes
of meningiomas: long-term analysis. Neurosurgery
56: 946–955, 2005
12) Niiro M, Yatsushiro K, Nakamura K, Kawahara Y,
Kuratsu J: Natural history of elderly patients with
asymptomatic meningiomas. J Neurol Neurosurg
Psychiatry 68: 25–28, 2000
13) Oya S, Kim SH, Sade B, Lee JH: The natural history
of intracranial meningiomas. J Neurosurg 114:
1250–1256, 2011
14) Braunstein JB, Vick NA: Meningiomas: the decision
not to operate. Neurology 48: 1459–1462, 1997
120
S. Nakasu et al.
15) Go RS, Taylor BV, Kimmel DW: The natural history
of asymptomatic meningiomas in Olmsted County,
Minnesota. Neurology 51: 1718–1720, 1998
16) Herscovici Z, Rappaport Z, Sulkes J, Danaila L,
Rubin G: Natural history of conservatively treated
meningiomas. Neurology 63: 1133–1134, 2004
17) Jadid KD, Feychting M, Höijer J, Hylin S, Kihlström L,
Mathiesen T: Long-term follow-up of incidentally
discovered meningiomas. Acta Neurochir (Wien)
157: 225–230; discussion 230, 2015
18) Olivero WC, Lister JR, Elwood PW: The natural
history and growth rate of asymptomatic meningiomas: a review of 60 patients. J Neurosurg 83:
222–224, 1995
19) Romani R, Ryan G, Benner C, Pollock J: Non-operative
meningiomas: long-term follow-up of 136 patients.
Acta Neurochir (Wien) 160: 1547–1553, 2018
20) Rubin G, Herscovici Z, Laviv Y, Jackson S, Rappaport
ZH: Outcome of untreated meningiomas. Isr Med
Assoc J 13: 157–160, 2011
21) Sonoda Y, Sakurada K, Saino M, Kondo R, Sato S,
Kayama T: Multimodal strategy for managing meningiomas in the elderly. Acta Neurochir (Wien) 147:
131–136; discussion 136, 2005
22) Yano S, Kuratsu J: Indications for surgery in patients
with asymptomatic meningiomas based on an extensive experience. J Neurosurg 105: 538–543, 2006
23) Lee EJ, Kim JH, Park ES, et al.: A novel weighted
scoring system for estimating the risk of rapid
growth in untreated intracranial meningiomas.
J Neurosurg 127: 971–980, 2017
24) Lee EJ, Park JH, Park ES, Kim JH: “Wait-and-See”
strategies for newly diagnosed intracranial meningiomas based on the risk of future observation
failure. World Neurosurgery 107: 604–611, 2017
25) Nakamura M, Roser F, Michel J, Jacobs C, Samii M:
The natural history of incidental meningiomas.
Neurosurgery 53: 62–70; discussion 70–71, 2003
26) Nakasu S, Onishi T, Kitahara S, Oowaki H, Matsumura
KI: CT Hounsfield unit is a good predictor of growth
in meningiomas. Neurol Med Chir (Tokyo) 59:
54–62, 2019
27) Yoneoka Y, Fujii Y, Tanaka R: Growth of incidental
meningiomas. Acta Neurochir (Wien) 142: 507–511,
2000
28) Nakasu S, Nakasu Y, Fukami T, Jito J, Nozaki K:
Growth curve analysis of asymptomatic and symptomatic meningiomas. J Neurooncol 102: 303–310,
2011
29) Chang V, Narang J, Schultz L, et al.: Computeraided volumetric analysis as a sensitive tool for
the m
anagement of incidental meningiomas. Acta
Neurochir (Wien) 154: 589–597; discussion 597, 2012
30) Zeidman LA, Ankenbrandt WJ, Du H, Paleologos N,
Vick NA: Growth rate of non-operated meningiomas.
J Neurol 255: 891–895, 2008
31) Webplotdigitizer: https://automeris.io/WebPlotDigitizer/
(Accessed on 2019 Mar. 28)
32) Kanda Y: Investigation of the freely available easyto-use software ‘EZR’ for medical statistics. Bone
Marrow Transplant 48: 452–458, 2013
33) Hirota K, Fujita T, Akagawa H, Onda H, Kasuya H:
Spontaneous regression together with increased
calcification of incidental meningioma. Surg Neurol
Int 5: 73, 2014
34) Islim AI, Mohan M, Moon RDC, et al.: Incidental
intracranial meningiomas: a systematic review and
meta-analysis of prognostic factors and outcomes.
J Neurooncol 142: 211–221, 2019
35) Kasuya H, Kubo O, Kato K, Krischek B: Histological characteristics of incidentally-found growing
meningiomas. J Med Invest 59: 241–245, 2012
36) Liu Y, Li F, Wang C: Clinical features and surgical
treatment of asymptomatic meningiomas. Turk
Neurosurg 25: 121–125, 2015
37) Ishi Y, Terasaka S, Yamaguchi S, et al.: Reliability
of the size evaluation method for meningiomas:
maximum diameter, ABC/2 formula, and planimetry
method. World Neurosurg 94: 80–88, 2016
38) Zeng L, Liang P, Jiao J, Chen J, Lei T: Will an
asymptomatic meningioma grow or not grow? A
meta-analysis. J Neurol Surg A Cent Eur Neurosurg
76: 341–347, 2015
39) Sughrue ME, Rutkowski MJ, Aranda D, Barani IJ,
McDermott MW, Parsa AT: Treatment decision
making based on the published natural history and
growth rate of small meningiomas. J Neurosurg 113:
1036–1042, 2010
40) Berhouma M, Jacquesson T, Jouanneau E, Cotton F:
Pathogenesis of peri-tumoral edema in intracranial
meningiomas. Neurosurg Rev 42: 59–71, 2019
41) Nakasu S, Nakajima M, Matsumura K, Nakasu Y,
Handa J: Meningioma: proliferating potential and clinic
oradiological features. Neurosurgery 37: 1049–1055,
1995
Address reprint requests to: Satoshi Nakasu, MD, Division
of Neurosurgery, Kusatsu General Hospital, Yabase
1660, Kusatsu, Shiga 525-8585, Japan.
e-mail: neuro-nakasu@kfx.biglobe.ne.jp
Neurol Med Chir (Tokyo) 60, March, 2020
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