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書き出し
Gold(I)-Catalyzed Reaction of Azido Alkynes for the Synthesis of Indole-Based Polycycles
概要
Among transition metal complexes, those based on gold possess an extraordinary selectivity toward
the activation of alkynes. Once an alkyne is subjected to a cationic gold catalyst, its pronounced π-acidity
results in the formation of an activated alkynyl gold complex 1 and unlocks its reactivity toward a broad
scope of nucleophiles (e.g., C, N, O) (Scheme 1). Through nucleophilic trans-addition, the generated vinyl
gold complex 2 can be further functionalized with diverse electrophiles, terminating the cascade via
deauration to 3. ...
