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Acknowledgements
This work was supported by a grant awarded to Hisao Haniu by the Japan Society for the Promotion of Science
KAKENHI (Grant Number, 16K15660), a grant awarded to Tamotsu Tsukahara by the Ito Foundation (Grant
Number, ken-1), and by the Japan Society for the Promotion of Science KAKENHI (Grant Number, 19K07322).
This work was the result of using research equipment shared in MEXT Project for promoting public utilization
of advanced research infrastructure (Program for supporting introduction of the new sharing system) Grant
Number JPMXS0422500320.
Author contributions
T.T., H.H., T.U. and Y.M. conceived and designed the project. T.T., Y.M. and H.H. acquired the data. LC-MS/MS
data was analyzed by Japan Lipid Technologies (Akita, Japan). T.T. and H.H. analyzed and interpreted all other
data, and T.T. wrote the manuscript. All authors have read and approved the final version of the article.
Competing interests
The authors declare no competing interests.
Additional information
Supplementary information is available for this paper at https://doi.org/10.1038/s41598-020-60781-1.
Correspondence and requests for materials should be addressed to T.T.
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